Equus caballus (horse): 100065679 Help Entry 100065679         CDS       T01058                                  Symbol TSC2 Name (RefSeq) tuberin isoform X2   KO K07207   tuberous sclerosis 2 Organism ecb  Equus caballus (horse) Pathway ecb04072   Phospholipase D signaling pathway ecb04115   p53 signaling pathway ecb04140   Autophagy - animal ecb04150   mTOR signaling pathway ecb04151   PI3K-Akt signaling pathway ecb04152   AMPK signaling pathway ecb04211   Longevity regulating pathway ecb04218   Cellular senescence ecb04714   Thermogenesis ecb04910   Insulin signaling pathway ecb04919   Thyroid hormone signaling pathway ecb05163   Human cytomegalovirus infection ecb05165   Human papillomavirus infection ecb05168   Herpes simplex virus 1 infection ecb05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100065679 (TSC2)    04151 PI3K-Akt signaling pathway     100065679 (TSC2)    04152 AMPK signaling pathway     100065679 (TSC2)    04150 mTOR signaling pathway     100065679 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100065679 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     100065679 (TSC2)    04218 Cellular senescence     100065679 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100065679 (TSC2)    04919 Thyroid hormone signaling pathway     100065679 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100065679 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100065679 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100065679 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100065679 (TSC2)    05163 Human cytomegalovirus infection     100065679 (TSC2)    05165 Human papillomavirus infection     100065679 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:ecb01009]     100065679 (TSC2) Protein phosphatases and associated proteins [BR:ecb01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100065679 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100065679 NCBI-ProteinID:  XP_005599119 Ensembl:  ENSECAG00000021222 VGNC:  24572 LinkDB All DBs Position 13:complement(41927187..41966103) Genome browser AA seq 1814 aa AA seqDB search MAKPASKDSGLKEKFKTLLGLGTPRPNPRTAEGRQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGILR ALFFKVIKDYPSNEDLHERLEVFKALTDNGKHITYLEEELAEFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRLMENRAYMEDAPLLRGAVFFVG MALWGAHRLYTLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYKRELQAVTWDI LLNIIERLLQQLQSLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDLEAYSASLEDVKTAVLGLLVILQTKLYTLPASHAMRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDYMEPERGSEKKAS GPLSPPTGPPGPASPGPATRPGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFNSPCSVDQLSSALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAADAFRCRSISVSEHVVRRIQTSLTSASLGSADENSMAQADDNLKNLHLE LTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLL GLDSGELQGCPELSSDPSVHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVGA LDASASHFPGGLTSPGPQTTPASKPEKASAGTQLPAQKEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPSPPPRSNTVASFFSLYQSSCQGKLHRSISWADSAVVLEEGSPGEANVPVEPPDLEDF EATLGTDRRCPRTEAYSRSSSTSSQEEKSFRGEELAVGGIPIERAVSSEGARPSVDLSFQ PSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGILDGEGAAWSAPGEES QGQSPAQPESPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVEREAFKSRAGASNTEKVP GINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQS TSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIM QAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITP LDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDI YPSKWIARLRHIKRLRHRIREEAQYSNSSLTLMQTHPPGHAKAPAQAPAEPMPTYETGQR KRLISSVDDFTEFV NT seq 5445 nt NT seq  +upstreamnt  +downstreamnt atggccaagccagcaagcaaagattcaggcttgaaggagaagttcaagactctgctggga ctgggaactccgaggccaaatcccaggactgcagagggcagacagacagagttcatcatc acggcggaaatcctgagagaactgagtgttgaatgtggcctcaacaatcgtatccgggtg atagggcagatctgtgaagtcgcaaaaacgaagaaatttgaagagcacgcagtggaagca ctctggaaggccgtcgcagacctgctgcagcctgagcggccacctgaagcccggcacgca gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcattctcagg gccctcttctttaaagtcatcaaggattacccctctaatgaagacctccacgaaagactg gaagttttcaaggccctcacggacaatgggaaacacatcacctacttggaagaagaactg gctgagtttgtcctgcagtggatggacatcggcctgtcctcagaattcctgctggtgctt gtgaacttggtcaaattcaacagctgttaccttgatgaatacatcgcatcgatggtccac atgatctgcctgctgtgcgtccagaccgtgtcctctgtggacatagaggtctctctgcag gtgctggatgccgtggtctgctacaactgcctgccggccgagagcctccccctcttcatc gtcaccctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg cggaacctcctgggcacccacctgggccacagtgccatctacaacatgtgccgcctcatg gagaacagagcctacatggaggacgccccgctgctgagaggagctgtgttctttgttggc atggctctatggggagcccaccggctctatactctcaagaactccccgacgtccgtgctg ccatcgttctatgaggccatgacctgtccgaatgaggtggtgtcctatgagattgtcctc tccataacaagactcatcaagaagtacaagagggagcttcaggctgtgacgtgggacatc ctgctgaacattattgaacgcctgcttcagcagctccagagcctggacagcccggaactc aggaccatcgtccatgacctgctgaccacggtggaagaactgtgtgatcagaatgagttc cacggctcccaggagagatactttgagcttgttgagagatgtgcagaccagaggcctgag tcctccctcttaaacttaataacctacagggctcagtcaatccatcctgcaaaggacggc tggattcacaacctacagttactgatggagagattcttcaggaacgaatctcgcagcgct gtgcgcatcaaggtgctggatgtcctgtccttcgtgttgctcatcaacaggcagttctac gaggaggagctgatcaactcagtggtcatctcacagctctcccacatccctgaggataaa gaccaccaggtccgaaagctggccacccagctgctggtggacctggccgaaggctgccat acccaccacttcaacagcctgttggacatcatcgagaaagtgattgcccgctccctctcc ccgccccccgagctggaggaaagagacctggaggcatactcagcctccttggaagatgtg aagaccgcggtcctggggctcctggtcatccttcagaccaagctgtacaccttgcctgcc agccacgcaatgcgtgtgtacgagacgctcgtcagccacatccagctccactacaagcac agctacaccctgcccattgccagcagcatccggctacaggccttcgatttcctgctgctg ctgcgggccgactcgttgcaccgcctcggtctgcccaacaaggacggggttgtgaggttc agcccctattgcctctgtgactacatggagccggagagaggctctgagaagaaggccagt ggtcccttgtcacctcccaccgggccgcctggcccagcgtctccaggccccgccacacgg cccggctctctgccctactctctcctcttccgtgtcctgctgcagtgcttgaagcaggag accgactggaaggtgctgaagcttgtgctcagcaagctccctgagtcactgcgctataag gtcctcattttcaactctccatgcagtgtggaccagctgtcctccgccctctgctctatg ctttcaggtcccaagaccctcgagcggctccgaggcaccccagaagggttctctagaacc gacctgcatttggctgtggttcccgtgctgacggcgctaatctcttaccacaactacctg gataaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgc gccagccagtgtgtggtggccctggccatctgcagcgtggagatgccagacatcatcatc aaagcattgcctgtcttggtcgtgaaactcacgcacatctcggccacagccagcatggcc attccgctcctcgagttcctgtcaactctggccaggctgcctcacctctacaggaacttc gccgcagagcagtacgcgagcgtgttcgccatctccctgccgtataccaacccctctaag ttcaaccagtacattgtgtgcctggcccatcatgtcatagccatgtggttcattaggtgc cgcctgcccttccggaaagattttgttccttacatcactaagggcctgcgctccaatgtc ctcctgtcttttgatgacacccctgagaaggacagcttcagagcacggagcaccagtctc aacgagaggccgaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacctgtgaaagaattcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcaggatccagacatccctcacgagtgccagcttgggg tctgcagatgagaactcaatggcccaggctgatgacaacttgaaaaatctccacttggag ctcacagaaacgtgtctggacatgatggccagatatgtgttctccaacttcacagcggtc cccaagaggtcccccgtgggagagttcctcctggctggcggcaggaccaaaacctggctg gttgggaacaagcttgtcaccgtgacaacgagtgtggggactggtacccggtcactgctg ggcctggactcaggagagctgcagggctgcccagagttaagctccgaccccagtgtgcac gtgagacagacaaaggaggcgccagccaagctggagtcccaggctgggcagcaggtgtgc cgcggggcccgggaccgggtccgctccatgtctgggggccatggccttcgcgttggtgcc ctggatgcttcagcctcccacttcccaggcggcctcacttccccgggcccacagaccaca ccagccagcaagcctgagaaggcctcagctggcacccagctcccagcgcagaaggagaag acgaacctggcagcctatgtgcccttgctgacccagggctgggctgagatcttggtccgg aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccccttctcc tcggacatcaacaacatgcctctgcaggagctctccaacgccctgatggccgctgagcgc ttcaaggagcgccgcgacacggccctgtacaagtcactgtcagtgccagcagctggctca gccaagccttccccacccccacggtctaacacagtggcctctttcttctccctgtaccag tccagttgccaaggaaagctgcacaggagcatttcctgggcagactctgcggtggttctg gaggagggaagtccaggcgaggctaatgtgccagtggaaccccccgacttagaggacttc gaggcaacactcggcacagacaggcgctgtccgcgcactgaagcttacagcaggtcgtct tcaacctccagccaggaggagaagtcattccgtggagaggagttggctgttggggggatc cccatcgagcgggccgtctcctctgagggagcccggccctctgtggacctctccttccag ccctcacagcccctaagcaagtccagctcctcacctgaactgcagaccctgcaggacatc cttggggaccctggggacaaggctgacgttggccggctgagccccgaggtcaaggcccgg tcacagtctgggatcctggatggggaaggcgctgcttggtcagccccaggcgaagagagc cagggccagagccctgctcagcctgagagtcccttgccttccagctgcccccgctccccc agtggcctgcggccccgaggctacaccatctctgattcagccccttcacgcaggggcaag agggtggagagggaagccttcaagagcagagctggggcctctaatactgagaaggtgccg ggcatcaaccccagcttcgtgttcctgcagctctaccattcgcctttcttcggcgacgag tccaacaagccaatccttttgcctaacgagtccttcgagcgatcggtgcagctccttgac cagatcccgtcctacgacacacacaagattgccgtcctgtacgtgggagaaggccagagc accagtgagctcgccatcctgtccaatgagcacggctcctacaggtacacggaattcctg acaggcctgggcaagctcatcgagctcaaggactgccagccagataaggtgtacctgggc ggcctggatgtgtgtggcgaggatggccagttcacctactgctggcacgacgacatcatg caagccgtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgttgc gacaagaagcgccacctgggcaatgatttcgtgtccattgtctacaacgactctggcgag gacttcaagctgggcaccatcaaaggccagttcaactttgtccatgtgattatcaccccc ctggactacgagtgcaacctggtgtcgctgcagtgcaggaaagacatggagggcctcgtg gacaccagcgtggccaagatcgtgtctgaccgcaacctcccttttgtggcccgccagatg gccctgcatgcaaatatggcctcgcaggtacaccacagccgctccaaccccactgacatc tatccctccaagtggattgccaggctccgccacatcaagcggctccgccaccggatccgg gaggaagcccagtactcgaactccagcctgaccctgatgcagacgcaccctccgggccac gccaaagccccagcacaggctccagccgagcccatgcccacctacgagacgggccagcgg aagcgcctcatctcttccgtggacgacttcacagagtttgtgtga

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