Equus caballus (horse): 100066679
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Entry
100066679 CDS
T01058
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100066679 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ecb03021
]
100066679 (SETX)
Enzymes [BR:
ecb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
100066679 (SETX)
5.6.2.5 RNA 5'-3' helicase
100066679 (SETX)
Transcription machinery [BR:
ecb03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
100066679 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
AAA_16
nSTAND3
Helicase_RecD
TniB
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
100066679
NCBI-ProteinID:
XP_023484968
Ensembl:
ENSECAG00000012019
VGNC:
22881
LinkDB
All DBs
Position
25:complement(35311028..35390363)
Genome browser
AA seq
2680 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLKRYASRTHSREFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERPSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTKIEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLSSLLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQADAVCDKVSEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTSAFARSSEKSSGNCSKGTSMMSSLSLHSLPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKVKPP
PCNTLVDLTPACKTPPASYTKEENEQIGKKSKKDIRCLENSSPTFSKEPMKADAYQVQES
LLIKASNTVEDNEQNYIKDIKLEDHLSTESCLKQSSKNLVNERAQDEVKISTRKQKSVKE
NSLHKRQNCTSRNGPEKGCDRGIIISTRLLTDSSTDFLEKVSTSNEDFPLKDDAVSKTSK
AKAKSQKDEICAKLSHVIKKQHRKSTLVNNAVNLEENRTVSNVENLFSRKDIGGQKGDSF
VHNLSLDPNGILDDKNGEQKSQSSLLLKKKQLKNEELDIFSSHEKSCQIQECHADDKDLV
SFTEMTNTFMKKTSPFKDPMTVIESREKEISKSTDQVSSNLREQAPSISPNSDTLTDSQI
DRDLHKLSLIAQASVIKFPSDSAQRNSSQLQRKVRDDKRCFTANQNKVGETCHEQVIIIS
DSDDDDDGDERILRFEKHTKQDKICVEKECPEQHIAVDNRNVEKKLIKEEETQSLLQFEE
SDSQFFEFESPCEVFSVWQDQKPDNKNSVQEDGKNSSLTHIVDITNDWGYDTDYVSEEVI
KKVSEGIEEHAEPQSTSISVEEFCEIEVKKPKRKQIEKPMAEDPLRPSSISKEVQPDILN
EKGLTENNFKSIDIKTTTPNSSIQRATTISLKKSSPKPHAYSKPVRKVPLSKTPKKTHSD
AKKGQNKNSNYLSCRTAPAVVPPKKFRQCPEPTSKVEKLGLKKAPRRAFELSQRSLEHIG
KLRDHGKTVGVVDTPKKTKLISQTSVKNNKKLLKNQDLQLQRQMRSRSQQNKQRCFDYES
TDTMKTRSRTAQNSDIFVPESARSDNKGGTEAIADSDGRQLIKCASSELEPVKTKYVSQG
TDDTCLLNQCNSVVLNGRIPTNEIIVSTSEEPLGGSDLTAHHLELAILKEQEPESNSDIE
EDNIFLTQRDPEDMDLCSQMENGNDKLIEVVHGKDTVQVEDDSVRQPQLESLSSTKCKYK
DCVETMKNEGEYCLKHSEVKAADEDVFRKPSLPLSSSKPWRPTTKIFSSRSTSRIAHLSK
SLENTSALPPALKNKSNGVQSILKAPQPASLVSQKPMGEVKSLCNVPHSQTLNNSNRQGY
KLPFGENKSFLASSPVSILLSSQSVSDTFVKEVLKWKYEMFVNFDQCGPPASLCQSISRP
VPVKFQDCGEYFNVFLPLMILNTFETVAQEWISSPNKEKFCQLHLRKFPADYKKYWEFVV
YLEECELAKQLHPKENDLVFLVPERLNGEKKAIERNCMQDPHEYHCGYVHKFRRTSVMRN
GKSEYSLSIQTQDNLPVNLNELVKCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPM
DFCTKDLLTTTSDRIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKT
IVGLLYRLLTENHRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKK
NPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQDMHRRKEYLDHQLD
ELSRQRALCRGGREVQRQELDEKIASVSKERQELASKIKEVQGRPQKTQNNIILESHVIC
CTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLP
PTVISMKAQDYGYDQSMMARFYKLLEENVEHNVISRLPILQLTVQYRMHPDICLFPSNYV
YNKSLKTNRLTETSRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKD
KRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRA
NATQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMDNEHWNELIQDAQKRGAIIKTCD
KNYKHDAMKILKLKPVLQRSLTHPSAVAPEVSRPQGGLPSNKLDSEFAKTSFASSLYHTP
SDSKETTVTAKDPERPSGQDWLRDPRLLRRMGMSPEAKGKCLMDPQSLSPQHPGATPPSG
EPGFPVIHQDVGSVQQSAAKGATLSNHKPHVQCDPPAASGDAATSRRKCDQEGMLSYRRE
TRAFSEGDQEKYSSVSHHTKRNSGWDKEEEDSSSKKRKVL
NT seq
8043 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcctggtggtatttccaccattgacttcctaaagcgc
tatgcatccaggacccactccagggaatttcaaacagctgatgaagacctctgttactgc
ttagagtgtgtggccgaataccataaagcaagggatgaattgccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaaaatccatgaaagcagaa
attggagatgatgatgaattgtatatagtagacaacaatggagaggcacaactgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaagcatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcatt
gaattggggcttttagaaagtccagacatttatacttcttctgtccttgaaaagggcaaa
ctgattcttctgccctcgcacatgtatgatactaccaactataaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
gacaaacaaaatgactttatgcaatcaatacttcacaccatggagaggccatcagatgat
gatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaactattatcaat
aatgtgagctacaatagagagattcaaaatatacggaacagctctgtaaggaccaagata
gaaccggagtcatatttggatgacatggtgacttgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattatccagtttgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctgtggttcatcccttttgttcaatccctcatggat
cttaaggatttgggtgtggcttatatagtagaggttattcatcatctgcactctgaagtc
aaagatgtcctcaaccaagcagatgctgtgtgtgacaaagtcagtgaattttttcttcta
attttggtgtcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggtt
agttcccaacaatgggttgaagccgttgtaaaatgtgccaaacttccaaccagtgcattt
gcacggagttctgagaaatcatctggaaattgctccaaaggaacatcaatgatgtcatct
ctgtcattgcattcactgccatctaactctgtacaacttgcgtgtgtgcaactgattaga
agtctccttaaagaaggttatcagcttgggcagcaaactctttgtaagcgattctgggat
aagctcaatttattcctgcgaggaaatctatctctaggttggcagctgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattcgaaacataaaagtcaaaccacct
ccttgtaacactttggtggatctgactcctgcgtgtaaaacccctcctgcatcttatact
aaagaggaaaatgaacaaataggaaagaagtctaaaaaagacatacgctgtctggaaaat
tccagcccaacgttttctaaagaaccaatgaaagctgatgcatatcaagtgcaggagagt
ctattgatcaaagcaagtaacactgtagaggataatgagcaaaattatataaaagacatc
aaactagaagaccatctttcaactgagtcatgtttaaagcagagtagtaaaaatcttgtc
aatgaaagagctcaagatgaagttaaaataagtacaaggaagcagaagtctgtgaaagag
aattccttacataaacgacagaattgtacttcaagaaatggtccagaaaaagggtgtgac
agaggaataataatatcaacacgtttgttgactgattctagcactgattttctggaaaag
gtatccacatcaaatgaagatttccctttaaaggatgatgctgtcagtaaaacctcaaaa
gcaaaagctaagtcacagaaagatgaaatctgtgctaagttatcacatgtgataaagaag
caacacaggaaaagtactttggtcaataatgctgtcaatttagaggaaaaccggactgta
tctaacgttgagaatttgttttcaaggaaagatataggaggtcagaaaggggatagcttt
gtacacaatctctctttagaccctaatggtattctggatgataaaaatggagagcaaaaa
tctcaaagcagtttactactgaaaaagaaacaattaaagaatgaagagttagatattttc
tcttcccatgaaaagagttgtcaaatacaagaatgtcatgctgatgataaagatttggtc
tcgtttacagaaatgactaatactttcatgaagaaaacatctccctttaaagatcccatg
actgtaattgaatcaagagagaaggaaattagcaagagtaccgatcaggtttcttctaat
ttgagagaacaggcccctagcatcagtcctaattctgacactttaacagattctcagata
gaccgagacctccacaaattgtctttaatagctcaggctagcgttattaagtttccatca
gattcagcgcaaagaaactcatcccagctacaaagaaaagtaagagatgataagagatgt
ttcacagctaaccaaaacaaagttggagaaacctgccatgaacaggtgattattatttca
gattctgatgatgatgatgatggtgatgaaagaattctgcgttttgagaaacacactaaa
caagataaaatatgtgttgagaaagaatgtccagagcagcatattgcagtagataataga
aatgtggaaaagaagctaataaaagaagaagagacacagtcccttttacagtttgaggaa
tctgattctcagttttttgagtttgaaagtccatgtgaagtgttttcagtttggcaagat
cagaaaccagacaacaagaattcagttcaagaggatggaaaaaattcatccttgactcat
atagttgatatcacaaatgattggggttatgatacagattatgtatctgaagaggttatt
aaaaaagtatcagagggcattgaagaacacgcagaaccacagagtactagtatttctgtt
gaggaattttgtgaaattgaagtaaaaaaacctaagagaaaacaaattgaaaaacctatg
gctgaagaccctttaaggccttcatctatcagcaaggaggtccagcctgatattcttaat
gagaaaggtctgactgaaaataattttaaaagtattgacataaagactacaactcccaat
tcaagtattcagagagccaccacgatttccctaaagaaatcttctccgaagcctcatgct
tattccaaacccgttaggaaagtcccactttctaaaacccctaagaaaacacattcagat
gccaaaaaaggacagaataaaaattcaaattacttaagttgtaggacagctcctgctgta
gtgccaccaaagaaatttcgccagtgtcctgaaccaacttcaaaagttgagaaacttggt
ctgaaaaaggctcctcgtagggcatttgagttgtctcagcggtctttagagcatataggt
aagttacgtgaccatggcaaaactgttggagtagttgataccccaaagaagactaaatta
atttctcagacttctgtcaaaaataataagaaattgctgaaaaatcaagatctgcagttg
caaaggcagatgagatccagatcacaacaaaataaacaaagatgttttgattatgaaagt
acagatactatgaaaacaaggtcacgcacagcgcagaattctgacatatttgtaccagaa
tcagctaggtcagataataaaggaggaactgaggcaattgctgacagtgatggcaggcaa
ttaataaaatgtgcatcttctgaactagaacctgtgaaaacaaaatatgtttcccagggg
actgatgatacttgtcttttgaaccagtgtaattctgtagtgttaaatggaagaatacca
acaaatgaaataattgtttctacttcagaggaacctttaggtggaagtgacctaacagca
catcatttagagctggcaattttgaaagagcaagagcctgaatccaacagtgatatagag
gaagataatatatttttaacacaacgtgaccctgaggatatggatttatgttcacaaatg
gagaatggtaatgataaactcattgaggtagttcatggaaaagatactgttcaggtagaa
gatgattctgtaagacagcctcagttggaatctttgagtagcacaaaatgtaagtacaaa
gattgtgttgaaactatgaaaaacgagggtgagtactgcttgaaacactctgaagttaaa
gcagcagatgaagatgtatttcgtaaacctagcttgcctctttcttcatctaaaccttgg
agacctaccactaagatttttagctcacgtagtacttcacgaattgctcatctttccaag
tctttggaaaatacctcagcgcttccaccagctctaaaaaataagtcaaatggggtacaa
tctattttgaaagcaccacagccagcctctcttgtgtctcagaagccaatgggtgaagtc
aagagtttgtgcaatgttcctcattctcagactctaaataattccaacagacaaggttac
aaacttccatttggtgaaaacaagtcttttttggcttcctctccagtaagcattctcttg
tcatcacagtctgtctctgacacctttgttaaagaggtcttaaaatggaaatatgaaatg
tttgtgaactttgatcagtgtgggcccccagcaagtctttgtcagtccatctcaagacct
gtgcctgtcaaatttcaagattgtggagaatatttcaacgtttttcttcctttgatgata
ctgaatacttttgaaacagtggcacaggaatggatcagctctccaaataaagagaaattc
tgtcagttacatttacgaaaatttcctgctgattataaaaaatactgggagtttgtggtt
tatcttgaagaatgtgaactagctaaacaacttcatccaaaggaaaatgatttggtgttt
ttggttcctgaaagactaaatggagagaagaaagctatagagagaaattgcatgcaagac
cctcatgaatatcattgtggttatgttcataaatttcgccgcacttcagtcatgcgtaat
gggaaatctgagtattccctttccatccagactcaagataatttgccagtcaatttaaat
gaactcgtgaaatgtattgtaatcagttctctggtaactacacaaaggaagttgaaagcc
atgtctttgctgagtggtcggaaccaactggccagagctgttctgaatccaaaccccatg
gacttctgtacaaaagatttacttactacaacatctgacagaattattgcctacctaaga
gatttcaatgaagaccaaaagaaagcgatagaaactgcatatgccatggtgaaacactcc
ccatcagttgccaagatatgtctgattcatggaccacctggaacaggaaaatcaaaaact
attgttggcctcctctatcgcctactgaccgagaaccataggaaggggcattcagatgaa
aactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcaccttccaatgcagct
gttgatgaacttatgaaaaaaattatcctcgaattcaaggaaaaatgtaaagacaagaag
aatcctttgggaaactgtggagatataaatttagtacgtctgggtccagagaagtctatt
aataatgaggtcctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagac
ttaccttctcatgttcaggacatgcatagaagaaaggaatatctggatcatcaactagat
gaactttcccgccagcgtgctttatgccgaggtggaagggaagtacagaggcaagaatta
gatgaaaaaattgccagcgtttcaaaagaaaggcaggaacttgcttcgaaaattaaagag
gttcaaggacgcccacaaaaaacacagaataatatcatcttagagtcccatgtcatctgc
tgcacattgagcaccagtggtggtttactgcttgagtctgcttttcgtgggcaaggaggt
gtcccctttagttgtgtcattgttgatgaggctgggcagtcttgtgaagttgaaacgctt
actccacttatccatcgttgtaacaagcttatccttgtaggagatcctaaacagctccct
cccacagtcatttctatgaaggcacaggattatggctatgaccagtcgatgatggctcgc
ttctacaaactgctggaagagaatgtagagcacaacgtgatcagcagactcccgatttta
cagctcaccgttcagtacagaatgcacccagacatatgtctcttcccttctaactatgtg
tataacaaaagcttgaaaacaaatagactaactgagaccagtcggtgttcgtcagactgg
ccatttcaaccctaccttgtgtttgatgtcggagatggttcagaaagacgggataatgac
tcatatgtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaagac
aaaagaagagatgttactttccgaaacattggcataataacccattacaaagctcagaag
acgatgattcagaaagatttggacaaagagtttgacggaaaagggccagcagaagtagat
accgtggatgccttccaggggcgtcagaaagattgtgtcattgttacctgtgtcagagca
aatgccacacaaggctcaattggatttctggcaagtttgcagagattgaatgtcaccatt
acacgagccaagtacagcctcttcatccttggtcatttgaggaccctcatggacaatgag
cattggaatgaactgattcaggatgctcagaagcgtggtgccattattaagacctgtgac
aaaaactataaacatgatgcaatgaagattctgaaactcaagcctgtactacagagaagt
ctgactcacccttcagctgtagccccagaggtgtccagaccccagggcggcttgcccagc
aacaagctagacagtgaatttgccaagacatcttttgcttcttccctgtaccacaccccc
tctgactccaaggaaactactgttactgcaaaggaccctgaaaggccttctggtcaggac
tggcttcgggacccacgactgcttaggaggatgggcatgagccctgaagccaaagggaaa
tgcctaatggatccacagtccttgagcccgcagcatcctggagcaacacctccctcggga
gagccaggcttccctgtaattcaccaggacgtgggcagcgtgcagcagtccgctgccaaa
ggagctaccctgagcaaccacaaacctcatgtgcagtgtgatcctccagctgctagtggt
gatgctgccacaagtagaagaaaatgtgaccaggaagggatgctcagctacagaagagag
accagggctttcagtgaaggggaccaggagaagtacagctctgtgagccatcacacaaag
aggaactctggctgggacaaggaggaggaggacagtagttcaaagaagagaaaagtttta
tag
DBGET
integrated database retrieval system
