Equus caballus (horse): 100066890 Help Entry 100066890         CDS       T01058                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 precursor   KO K10160   toll-like receptor 4 Organism ecb  Equus caballus (horse) Pathway ecb04064   NF-kappa B signaling pathway ecb04066   HIF-1 signaling pathway ecb04145   Phagosome ecb04151   PI3K-Akt signaling pathway ecb04217   Necroptosis ecb04613   Neutrophil extracellular trap formation ecb04620   Toll-like receptor signaling pathway ecb04621   NOD-like receptor signaling pathway ecb04936   Alcoholic liver disease ecb05132   Salmonella infection ecb05133   Pertussis ecb05134   Legionellosis ecb05135   Yersinia infection ecb05140   Leishmaniasis ecb05142   Chagas disease ecb05144   Malaria ecb05145   Toxoplasmosis ecb05146   Amoebiasis ecb05152   Tuberculosis ecb05161   Hepatitis B ecb05162   Measles ecb05164   Influenza A ecb05170   Human immunodeficiency virus 1 infection ecb05171   Coronavirus disease - COVID-19 ecb05205   Proteoglycans in cancer ecb05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ecb05321   Inflammatory bowel disease ecb05323   Rheumatoid arthritis ecb05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100066890 (TLR4)    04066 HIF-1 signaling pathway     100066890 (TLR4)    04151 PI3K-Akt signaling pathway     100066890 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100066890 (TLR4)   09143 Cell growth and death    04217 Necroptosis     100066890 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100066890 (TLR4)    04620 Toll-like receptor signaling pathway     100066890 (TLR4)    04621 NOD-like receptor signaling pathway     100066890 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100066890 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100066890 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100066890 (TLR4)    05161 Hepatitis B     100066890 (TLR4)    05171 Coronavirus disease - COVID-19     100066890 (TLR4)    05164 Influenza A     100066890 (TLR4)    05162 Measles     100066890 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     100066890 (TLR4)    05135 Yersinia infection     100066890 (TLR4)    05133 Pertussis     100066890 (TLR4)    05134 Legionellosis     100066890 (TLR4)    05152 Tuberculosis     100066890 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     100066890 (TLR4)    05144 Malaria     100066890 (TLR4)    05145 Toxoplasmosis     100066890 (TLR4)    05140 Leishmaniasis     100066890 (TLR4)    05142 Chagas disease     100066890 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     100066890 (TLR4)    05321 Inflammatory bowel disease     100066890 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100066890 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100066890 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ecb04131]     100066890 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:ecb04054]     100066890 (TLR4)    04090 CD molecules [BR:ecb04090]     100066890 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:ecb00536]     100066890 (TLR4) Membrane trafficking [BR:ecb04131]  Endocytosis   Phagocytosis    Toll-like receptors     100066890 (TLR4) Pattern recognition receptors [BR:ecb04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    100066890 (TLR4) CD molecules [BR:ecb04090]  Proteins   100066890 (TLR4) Glycosaminoglycan binding proteins [BR:ecb00536]  Hyaluronan   Cell surface receptors    100066890 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_5 LRR_6 LRR_NXF1-5 LRR_9 LRR_EndoS LRR_Zer-1 ThsB_TIR Pentapeptide_4 ANG-1 Motif Other DBs NCBI-GeneID:  100066890 NCBI-ProteinID:  NP_001093239 Ensembl:  ENSECAG00000010339 UniProt:  Q9MYW3 LinkDB All DBs Position 25:22396072..22406448 Genome browser AA seq 843 aa AA seqDB search MMPPTRLAGTLIPAMAFLSCLRPESWDPCVQVVPNTTYQCMDLNLYKIPENIPTSTKELD LSFNPLKELGSHSFSNFPELQVLDLSRCEIEMIEDDAYQGLNHLSTLILTGNPIRSLALG AFSGLSSLQTLVAVETKLSSLEKFPIGHLKTLKELNVAHNLIHSFKLPEYFSKMPNLEHL DLSNNKIQNISHEDLRVLHQMPLLNLSLDLSLNPLEFIQPDAFKEIKLHKLTLRSNFDSI DVMKSCIQGLAGLKVNRLVLGEFKNERKLERFDTSALRGLHNLTIEEFRLAYIDNYSSKD SIDLLNCLANISKISLVSLDLGNLQDFPKGFGWQDFELVNCRIEGFPTLELTSLKRLVFT SNKDMKSFNEVKLPSLEFLDLSRNRLSFKSCCSEADLKTTRLKHLDLSFNDVISMSSNFM GLEQLEHLDFQHSTLKQASDFPVFLSLKNLRYLDISYTNTRVVFHGIFDGLVSLQVLKMA GNSFKDNFLPNIFREMTNLTTLDLSKCNLEQVSQEAFCLLPRLRVLNMSHNNLLFLDMLP YKPLHSLQILDCSFNRIVAFKWQELQHFPSSLASLNLTQNDFACVCEYQSFLQWVKDQRQ LLVEVEHLVCAIPLQMRGMPVLGFNNATCQISKTIVGGSVFSILMVSVIAVLVYKFYFHL MLLAGCKKYGRGESIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAI AANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLHKLEKSL LRQQVELYRLLNRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPAGTADAAESRQHDAE TST NT seq 2532 nt NT seq  +upstreamnt  +downstreamnt atgatgccgcccacccgcctggctgggactctgatcccagccatggccttcctctcctgc ctgagacccgagagctgggacccttgcgtgcaggtggttcctaacactacttaccaatgc atggacctgaatctctacaaaatccctgagaacatccccacatcaaccaaggaactggac ctgagctttaaccccttgaaggagttaggcagccatagcttctccaacttcccagaactg caggtgctggatttgtccaggtgtgaaattgagatgattgaagatgatgcatatcagggc ctcaaccatctctccaccttgatattgacaggaaatcctatcaggagcttagccctggga gccttttctggactctccagtttacagacgctggtggccgtggagacaaagctttcatct ctagagaagttccccattggacatctcaagaccttgaaggagcttaatgtggctcataat cttatccattccttcaagttacccgagtatttttctaaaatgcccaacctggagcacttg gacctttccaataacaagatccaaaatatttctcatgaagacttgcgtgtgctacatcaa atgcccttactcaacctttctttagacttgtccctgaatcctttagagtttatccaacca gatgcctttaaagaaattaagctccataaactgactttgagaagtaattttgatagtata gatgtaatgaaatcttgtattcaaggactggctggtttaaaagtcaatcggttggttctt ggagaatttaaaaatgaaaggaaattggaaagatttgacacatctgccctgcgcggactg cacaatttgacgattgaagaattccggttagcatacattgataattacagctcaaaggat tctattgatttacttaattgtttggcaaatatttctaaaatttctctggtgagtctggat ttaggcaatctacaagattttcctaaaggtttcggatggcaagacttcgaattggttaac tgtagaattgaaggatttcccacattggagctcacctctctcaaaaggttggttttcact tccaacaaagatatgaaatcttttaatgaagttaagctaccaagccttgagtttctagat ctcagcagaaatcgcttgagtttcaagtcctgctgttctgaggctgatttgaagacaacc agactgaagcatttagatctgagcttcaatgatgttatttccatgagttcaaacttcatg ggcttagagcaactagaacatctggatttccagcattccactttgaaacaggccagtgat tttccagtattcttatccctcaaaaacctccgttatcttgatatttcttacactaacacc cgagttgtcttccatggcatctttgatggcttggtcagcctccaagtcttgaaaatggct ggcaattcttttaaggacaacttccttccaaatatcttcagagagatgactaacctgacc accctggacctttctaagtgtaacctggaacaggtgtcccaggaggcattttgcttactc cctcgacttcgggtgttaaatatgagtcacaataacctcctgttcttggatatgcttcct tacaaacctctccattccctccagattctggattgcagttttaatcgtattgtggccttc aagtggcaagaactgcagcattttccaagtagtctagcttccttaaatcttactcaaaat gactttgcttgtgtttgtgaataccagagttttctgcagtgggtcaaggaccagaggcag ctcttggtggaagttgaacacttggtgtgtgcaatacccttacagatgcggggcatgccc gtgctgggttttaacaatgccacctgtcagattagcaagactatcgttggcgggtcggtt ttcagtatactcatggtttctgtcatagcagttctggtctataagttctatttccacctg atgcttcttgctggctgcaaaaagtatgggagaggtgaaagcatctatgatgcctttgtt atctactcaagccaggacgaagactgggtgaggaatgaattggtaaagaacttggaggag ggggtgcccccctttcaactctgccttcactacagagacttcattcctggtgtggccatc gctgccaacatcatccaggaaggtttccacaaaagccggaaagttattgtcgtggtgtcc cagcacttcattcagagccgatggtgtatctttgagtatgagattgcccagacctggcag tttctgagcagtcgtgctggcatcatcttcatcgtcctgcacaagctggagaagtccctg ctccggcagcaggtggagctgtatcgccttctcaacaggaacacttacctggagtgggag gacagtgtcctggggcggcacatcttctggagacgactcaggaaagccttgctggatggt aaaccgtggagtccagcaggaacagcagatgcagcagaaagcagacaacatgatgcagaa acctctacctga

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