Equus caballus (horse): 100067216
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Entry
100067216 CDS
T01058
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00520
Amino sugar and nucleotide sugar metabolism
ecb00541
Biosynthesis of various nucleotide sugars
ecb01100
Metabolic pathways
ecb01250
Biosynthesis of nucleotide sugars
Module
ecb_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
100067216 (GNE)
00541 Biosynthesis of various nucleotide sugars
100067216 (GNE)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
100067216 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
100067216 (GNE)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Peptidase_M9
Glucokinase
zf-CCCH_Mcm10
Motif
Other DBs
NCBI-GeneID:
100067216
NCBI-ProteinID:
XP_001497363
Ensembl:
ENSECAG00000014124
UniProt:
A0A5F5PZU5
LinkDB
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Position
25:complement(1514629..1556775)
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AA seq
753 aa
AA seq
DB search
MEINVYPYSQWGFQGPHELYFKNLSRREKQVMEKNGNNRKLRVCVATCNRADYSKLAPIM
FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG
LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA
ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV
KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG
IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE
NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF
PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI
LQMCVEAASEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH
LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH
LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ
AAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS
SVQDVDVVVSDLVDPALLGAASMVLDYTTRRVY
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atggaaatcaacgtgtatccttacagccagtggggctttcaaggacctcacgaactctat
tttaagaatctctcaagacgagaaaaacaagtcatggagaagaatggaaataaccgaaag
cttcgggtttgcgttgctacttgcaaccgtgccgattattctaaacttgccccgatcatg
tttggcattaaaacagaacctgagttctttgaacttgatgtggtggtacttggctctcac
ctgatagatgactatggaaacacatatcgcatgattgaacaagatgactttgacattaac
accaggctacacacgatcgttagaggggaagatgaggcagctatggtggagtcagtaggc
ctggccctagtgaagctaccagatgtccttaatcgcctgaagcctgatatcatgattgtt
catggagacaggtttgatgccctggctctggctacgtctgctgccttgatgaacatccga
atccttcacattgaaggtggggaagtcagtggaaccattgatgactctatcagacatgct
ataacaaaactagctcattatcatgtgtgctgcacccgaagtgctgagcaacacctcata
tccatgtgtgaggaccatgatcgcatccttttggcaggctgcccttcctatgataaactt
ctctctgccaagaacaaagactacatgagtatcattcggatgtggctaggtgatgatgta
aaatctaaagattacattgttgcactacagcaccctgtgactactgacattaagcattcc
ataaaaatgtttgaattaacattggatgcacttatctcatttaacaagcggaccctagtt
ctgtttccaaatattgatgcagggagcaaagagatggtacgagtgatgcggaagaagggc
attgagcatcatcccaattttcgtgcagttaaacacgtcccatttgaccagtttatccag
ttggttgcccatgctggttgtatgattgggaacagcagctgtggggtacgagaggtggga
gcttttgggacacccgtgatcaacctaggaacacgtcagattggaagagaaacaggggaa
aatgtccttcatgtccgggatgctgatacccaagacaaaatactgcaagcgctgcacctt
cagttcggtaaacagtacccttgttcaaagatatatggggatggaaatgctgttccaagg
attttgaagtttctcaaatctattgatcttcaagagccactacaaaagaaattctgtttt
cctcctgtgaaggagaatatctctcaagatattgaccatattcttgaaactctaagtgcc
ttggctgttgatcttggtgggacaaacctccgagttgcaatagtcagcatgaagggtgaa
atagttaagaagtatactcaattcaatcctaaaacctatgaagagaggattaatttaatc
ctacagatgtgcgtagaagctgcatcagaagctgtaaaactgaactgcagaattttggga
gtaggcatttccactggtggccgtgtaaatcctcgggaaggaattgtgctccattcaacc
aaactgattcaagaatggaactctgtggacctcaggacccccctatctgacactttgcat
ctccccgtgtgggtggacaacgatggcaactgtgctgccctggcggagaggaaatttggt
caaggaaagggcctggaaaactttgtgacactgatcacaggcacaggaattggcgggggg
atcatccatcagcatgaactgatccacggaagctccttctgtgctgcagaactcggccac
cttgttgtgtctctggatgggcctgattgttcctgtggaagccatgggtgtattgaagca
tatgcctctggaatggccttgcagagggaagcgaaaaaactgcatgatgaagacctgctg
ttggtggaagggatgtcagtgccaaaagatgaagccgttggtgccctccatctcatccaa
gctgcaaaacttggcaacgtgaaggcccagagcatcttgaggacagctggaacggctttg
ggtcttggggttgtaaacatcctccacactatgaatccttccctcgtgatcctctctgga
gtcctagccagtcactatatccacatcgtcaaagacgtcatccgccagcaggccttgtcc
tcggttcaggacgtggacgtggtggtttcagatttggtggaccccgccctgcttggtgcc
gccagcatggttctggactacacgactcgcagggtctactag
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