Equus caballus (horse): 100068475
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Entry
100068475 CDS
T01058
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
ecb04927
Cortisol synthesis and secretion
ecb04934
Cushing syndrome
ecb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100068475 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
100068475 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100068475 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100068475 (PDE8A)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100068475 (PDE8A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PDE8A_N
PDE8_3rd
PAS_4
PAS_3
PAS_8
SPO22
Motif
Other DBs
NCBI-GeneID:
100068475
NCBI-ProteinID:
XP_005602820
Ensembl:
ENSECAG00000007337
VGNC:
21256
LinkDB
All DBs
Position
1:complement(92983680..93118595)
Genome browser
AA seq
676 aa
AA seq
DB search
MYCKQKEGESQVEGLKCKKDEEQENGGYGRYVENPSLMACYNELLQLEFGEVRSQLKLRA
CNSIFTALEKSQEAIEITSEDHIIQYANPAFETTMGYQSGELIGKELAEVPINEKKADLL
DTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVVGQGGKIRHYVSIIRVCNGNNKAE
KITECVQSDSHTDNQSGKHKDRRKSSLDVRAVASRASEVSSQRRHSSMARIHSMTIEAPI
TKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHASDLVGGLMSDGL
RRLSGNEYVLSTKNLQQVSSSMITPISLHDVPPRIARAMENEECWHFDIFELEAATHQRP
LIYLGLKIFARFGICEFLNCSETTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLC
RERIKQTLDPVDEAAALIAATVHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALA
FQLTTGDDKCNIFKNLGRNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAALEE
NGETDKDQEAINTMLRTPENRTLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTD
EEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVDLPELMQHLDNNFKYW
KGLDEMKLRSLRPPPE
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atgtactgcaagcagaaggaaggtgaatcccaagtggaaggcctgaaatgcaagaaggat
gaagagcaagaaaatggtggatatgggaggtatgtggaaaaccccagcctcatggcctgt
tacaacgaactgctccagctggagtttggagaggtgcgatcacagctgaaactcagggct
tgtaactcaatattcactgcgttagagaaaagtcaagaagcaattgaaattacgagtgaa
gaccacattatacagtatgcaaatcctgcatttgaaacaacaatgggctatcagtcaggt
gaattaataggaaaggaattagcagaagtgcctataaatgaaaaaaaggctgatttgctc
gatactataaattcatgcatcaggataggcaaggagtggcaaggaatttactatgccaaa
aagaaaaacggagataacatacaacaaaatgtgaagataatacctgtcgttggacaggga
ggaaaaattagacactatgtgtccattatcagagtgtgcaatggcaacaataaggctgag
aaaataactgaatgtgttcagtctgacagtcatacagataatcagtcaggcaaacataaa
gacaggagaaaaagctcactagatgtcagagctgttgcctctcgagcaagtgaagtttcc
agccagagacgacactcctccatggcccggatacattccatgacgattgaggcacccatc
accaaggtaatcaatattatcaatgctgcccaggaaagcagtcccatgcctgtgacagaa
gccttagaccgtgtgctggaaattctaagaaccactgaattatattcaccgcagttcggt
gctaaggatgatgatcctcatgccagtgacctcgttggaggcttaatgtctgatggtttg
cgaagactatctgggaatgagtatgttctttcaaccaaaaatcttcagcaggtttcaagc
agtatgatcactcccatctcccttcatgatgtcccaccacggatagctcgggccatggag
aatgaagagtgctggcactttgatatctttgaactggaggctgccactcatcaaaggcct
ttgatttatcttggtctcaaaatatttgctcgctttggaatctgtgaatttttaaattgc
tccgagacaacactgagatcgtggttacaaattattgaagccaattatcattcttctaac
ccctaccacaattctacacattctgctgatgtccttcatgccactgcctattttctctgc
agagagaggataaagcaaactttagatccggttgacgaggctgctgccctcattgcagcc
actgttcacgacgtggaccaccctgggagaaccaactccttcctgtgcaatgctggaagc
gagctggccattttgtataatgacactgctgtgctggagagccaccacgcagccttggcc
ttccagctgaccactggagacgataaatgcaatatctttaaaaacttgggaaggaatgac
tatcggaccctgcgccagggtattatcgacatggtcttagccacagaaatgacaaagcac
ttcgagcatgtcaacaagtttgtcaacagtatcaacaagcccttggcagcactagaagaa
aatggggaaaccgataaagatcaagaagccataaacactatgctcaggactccagagaac
cggactctgatcaaacgaatgctgattaagtgtgctgatgtgtccaatccctgccgaccc
ctggaacagtgcattgagtgggctgcacgcatctcagaagaatatttttctcagactgat
gaagagaagcggcaggacttacctgtggtgatgccagtttttgaccgaaatacctgcagc
atccccaaatcccaaatctcgttcatcgactacttcatcacagacatgtttgatgcttgg
gacgcctttgtagacctgcctgagttaatgcagcatcttgacaacaactttaaatactgg
aaaggactggatgagatgaagctgcggagcctccgaccgcctcctgaatag
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