Equus caballus (horse): 100069870
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Entry
100069870 CDS
T01058
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb01522
Endocrine resistance
ecb04012
ErbB signaling pathway
ecb04015
Rap1 signaling pathway
ecb04062
Chemokine signaling pathway
ecb04081
Hormone signaling
ecb04137
Mitophagy - animal
ecb04144
Endocytosis
ecb04360
Axon guidance
ecb04370
VEGF signaling pathway
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb04530
Tight junction
ecb04540
Gap junction
ecb04611
Platelet activation
ecb04613
Neutrophil extracellular trap formation
ecb04625
C-type lectin receptor signaling pathway
ecb04727
GABAergic synapse
ecb04750
Inflammatory mediator regulation of TRP channels
ecb04810
Regulation of actin cytoskeleton
ecb04912
GnRH signaling pathway
ecb04915
Estrogen signaling pathway
ecb04917
Prolactin signaling pathway
ecb04919
Thyroid hormone signaling pathway
ecb04921
Oxytocin signaling pathway
ecb04926
Relaxin signaling pathway
ecb05100
Bacterial invasion of epithelial cells
ecb05135
Yersinia infection
ecb05152
Tuberculosis
ecb05161
Hepatitis B
ecb05163
Human cytomegalovirus infection
ecb05167
Kaposi sarcoma-associated herpesvirus infection
ecb05168
Herpes simplex virus 1 infection
ecb05203
Viral carcinogenesis
ecb05205
Proteoglycans in cancer
ecb05207
Chemical carcinogenesis - receptor activation
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05219
Bladder cancer
ecb05417
Lipid and atherosclerosis
ecb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100069870 (SRC)
04015 Rap1 signaling pathway
100069870 (SRC)
04370 VEGF signaling pathway
100069870 (SRC)
09133 Signaling molecules and interaction
04081 Hormone signaling
100069870 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100069870 (SRC)
04137 Mitophagy - animal
100069870 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100069870 (SRC)
04520 Adherens junction
100069870 (SRC)
04530 Tight junction
100069870 (SRC)
04540 Gap junction
100069870 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100069870 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100069870 (SRC)
04613 Neutrophil extracellular trap formation
100069870 (SRC)
04625 C-type lectin receptor signaling pathway
100069870 (SRC)
04062 Chemokine signaling pathway
100069870 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
100069870 (SRC)
04915 Estrogen signaling pathway
100069870 (SRC)
04917 Prolactin signaling pathway
100069870 (SRC)
04921 Oxytocin signaling pathway
100069870 (SRC)
04926 Relaxin signaling pathway
100069870 (SRC)
04919 Thyroid hormone signaling pathway
100069870 (SRC)
09156 Nervous system
04727 GABAergic synapse
100069870 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100069870 (SRC)
09158 Development and regeneration
04360 Axon guidance
100069870 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100069870 (SRC)
05207 Chemical carcinogenesis - receptor activation
100069870 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
100069870 (SRC)
05203 Viral carcinogenesis
100069870 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
100069870 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
100069870 (SRC)
05168 Herpes simplex virus 1 infection
100069870 (SRC)
05163 Human cytomegalovirus infection
100069870 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
100069870 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
100069870 (SRC)
05152 Tuberculosis
100069870 (SRC)
05100 Bacterial invasion of epithelial cells
100069870 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100069870 (SRC)
05418 Fluid shear stress and atherosclerosis
100069870 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100069870 (SRC)
01522 Endocrine resistance
100069870 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100069870 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ecb04131
]
100069870 (SRC)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100069870 (SRC)
Protein kinases [BR:
ecb01001
]
Non-receptor tyrosine kinases
SRC family
100069870 (SRC)
Membrane trafficking [BR:
ecb04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100069870 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
100069870 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100069870 (SRC)
Macropinocytosis
Kinases
100069870 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100069870
NCBI-ProteinID:
XP_023482301
Ensembl:
ENSECAG00000012072
VGNC:
23571
UniProt:
F6QH40
LinkDB
All DBs
Position
22:28602144..28651787
Genome browser
AA seq
551 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAESAHGPGAFPAAQTPSKPASADGHRGAPAPFAPAAAEPK
LFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKVDV
SQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLL
LNVENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNS
LQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVW
MGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMS
KGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKV
ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP
YPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS
TEPQYQPGENL
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaaaagcaagcccaaggacgccagccagcggcgccgcagcctggagccg
gccgagagcgcgcacgggcccggcgccttccccgccgcgcagacccccagcaagccggcc
tcggcggacggccaccgcggcgcccccgcgcccttcgcccccgcggccgccgagcccaag
ctcttcgggggcttcaactcctcggacacggtcacgtccccgcagcgggccgggccgctg
gccggcggagtgaccacctttgtggctctctatgactatgagtcgcgcacagagactgac
ctctccttcaagaagggggagcggctccagattgtcaacaacacgaggaaggtggatgtc
agccagacctggttcacattcagatggctgcaaagagagggagactggtggctcgcccac
tcgctcagcacgggacagacgggctacatacccagcaactatgtggcgccctccgactcc
atccaggccgaggagtggtactttggcaagatcaccagacgggagtcagagcggttactg
ctcaacgtggagaacccgagagggaccttcctagtgcgagaaagcgagaccacaaaaggc
gcctactgcctctccgtgtccgactttgacaacgccaagggcctcaacgtgaagcattac
aagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttcaacagc
ctgcagcagctggtggcctactactccaaacacgctgacggcctgtgtcaccgcctcacc
accgtgtgccccacgtccaagccacagactcagggcctggccaaggacgcctgggagatc
ccccgggagtcgctgcggctggaggtcaagctgggccagggctgcttcggagaggtgtgg
atggggacctggaacggcaccaccagggtggccatcaaaaccctcaagccgggcacgatg
tccccagaggccttcctgcaggaggcccaggtcatgaagaagctgcggcacgagaagctg
gtgcagctgtacgcggtggtgtcggaggagcccatctatatcgtcacggagtacatgagc
aaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggctgcctcag
ctggtggacatggctgctcagatcgcctccggcatggcgtacgtggagcgaatgaactac
gtgcaccgggacctccgtgctgccaacatcctggtcggagagaacctcgtgtgcaaggtg
gccgacttcgggctggctcggctcatcgaggacaacgagtacacggcccggcaaggtgcc
aaattccccatcaagtggacggctccagaagctgccctctacggccgcttcaccatcaag
tcggatgtgtggtcctttgggatcctgctgacagagctcacgacaaagggacgggtgccc
taccctgggatggtcaacagagaggtcctggaccaagtggagcggggctaccgcatgccc
tgcccgcccgagtgtcccgagtccctgcacgacctcatgtgccagtgctggcggaaggag
ccggaggagcggcccaccttcgagtacctgcaggccttcttggaggactacttcacatcc
actgagccccagtaccagcccggggagaacctatag
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