KEGG   Equus caballus (horse): 100070334
Entry
100070334         CDS       T01058                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04022  cGMP-PKG signaling pathway
ecb04137  Mitophagy - animal
ecb04141  Protein processing in endoplasmic reticulum
ecb04151  PI3K-Akt signaling pathway
ecb04210  Apoptosis
ecb04211  Longevity regulating pathway
ecb04261  Adrenergic signaling in cardiomyocytes
ecb04668  TNF signaling pathway
ecb04720  Long-term potentiation
ecb04722  Neurotrophin signaling pathway
ecb04725  Cholinergic synapse
ecb04728  Dopaminergic synapse
ecb04911  Insulin secretion
ecb04912  GnRH signaling pathway
ecb04915  Estrogen signaling pathway
ecb04918  Thyroid hormone synthesis
ecb04922  Glucagon signaling pathway
ecb04925  Aldosterone synthesis and secretion
ecb04926  Relaxin signaling pathway
ecb04927  Cortisol synthesis and secretion
ecb04928  Parathyroid hormone synthesis, secretion and action
ecb04932  Non-alcoholic fatty liver disease
ecb04934  Cushing syndrome
ecb04935  Growth hormone synthesis, secretion and action
ecb05010  Alzheimer disease
ecb05012  Parkinson disease
ecb05014  Amyotrophic lateral sclerosis
ecb05020  Prion disease
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05030  Cocaine addiction
ecb05031  Amphetamine addiction
ecb05034  Alcoholism
ecb05161  Hepatitis B
ecb05163  Human cytomegalovirus infection
ecb05166  Human T-cell leukemia virus 1 infection
ecb05203  Viral carcinogenesis
ecb05207  Chemical carcinogenesis - receptor activation
ecb05215  Prostate cancer
ecb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100070334 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100070334 (ATF4)
   04668 TNF signaling pathway
    100070334 (ATF4)
   04022 cGMP-PKG signaling pathway
    100070334 (ATF4)
   04151 PI3K-Akt signaling pathway
    100070334 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100070334 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    100070334 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100070334 (ATF4)
   04922 Glucagon signaling pathway
    100070334 (ATF4)
   04912 GnRH signaling pathway
    100070334 (ATF4)
   04915 Estrogen signaling pathway
    100070334 (ATF4)
   04926 Relaxin signaling pathway
    100070334 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    100070334 (ATF4)
   04918 Thyroid hormone synthesis
    100070334 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    100070334 (ATF4)
   04925 Aldosterone synthesis and secretion
    100070334 (ATF4)
   04927 Cortisol synthesis and secretion
    100070334 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100070334 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    100070334 (ATF4)
   04728 Dopaminergic synapse
    100070334 (ATF4)
   04720 Long-term potentiation
    100070334 (ATF4)
   04722 Neurotrophin signaling pathway
    100070334 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    100070334 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100070334 (ATF4)
   05203 Viral carcinogenesis
    100070334 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100070334 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100070334 (ATF4)
   05161 Hepatitis B
    100070334 (ATF4)
   05163 Human cytomegalovirus infection
    100070334 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100070334 (ATF4)
   05012 Parkinson disease
    100070334 (ATF4)
   05014 Amyotrophic lateral sclerosis
    100070334 (ATF4)
   05020 Prion disease
    100070334 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    100070334 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    100070334 (ATF4)
   05031 Amphetamine addiction
    100070334 (ATF4)
   05034 Alcoholism
    100070334 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100070334 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100070334 (ATF4)
   04934 Cushing syndrome
    100070334 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ecb03000]
    100070334 (ATF4)
Transcription factors [BR:ecb03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100070334 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 Nop53 DUF3450 OVT1 ZapB DUF4407 Asd-4 bZIP_Maf KIF21A Fib_alpha
Other DBs
NCBI-GeneID: 100070334
NCBI-ProteinID: XP_023487292
LinkDB
Position
28:37457814..37459741
AA seq 334 aa
MADTSFLSSAAFGGDWMSLFDPSALGAEEGFGLLDDYLEVARHSEPHGFPGDKAKAGSSE
WLLVDGLVGAPDVGREDAFSGTDWMVEKVDLKEFDLDALLGFDDEFLATLDGTCDPFDSL
VQESDQDPPPAASPIGPLPESVPGVEPVAPLTFLQPLALSPGAVPFAQEHSFSLELGSEV
DIEGDRRAEPAACPAASVKEEDDSSDSDSGVCMSPGSSPGSPQRSPSASGSPGAGRASAR
PKPYDPPAEKAVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEQKN
EALKERADALAKEIQYLKDLIEEVRRARGRRRAP
NT seq 1005 nt   +upstreamnt  +downstreamnt
atggccgacacgagcttcctgagcagcgcggcgttcgggggggactggatgtccctcttc
gacccgtcggctttgggggctgaagaaggtttcggcctcctcgacgactacctggaggtg
gccaggcactccgaacctcatgggttccccggcgacaaggcgaaggcgggctcctccgag
tggctgctggtggacgggctggtgggcgcgcccgacgtcggccgggaggatgctttctcc
gggaccgactggatggtggagaaggtggacctgaaggagttcgacctggacgccctgctg
ggtttcgatgacgagttcttggccacgctggacggcacgtgcgatcctttcgactccctc
gtccaggagtcggatcaggacccccctccggccgcgagcccgattggccccctcccggag
agcgtccctggggtcgagccggtggcccccttgaccttcctgcagcccctcgctctctcc
ccgggggccgtgcccttcgcccaggagcattccttcagcctggagctgggcagcgaagtg
gacatcgagggggaccggagggcggagccggcggcctgccccgccgcgagtgtgaaggag
gaggacgactcctcggacagcgacagcggcgtctgcatgagcccaggctcctccccgggc
tccccccagcgcagcccctccgcctcgggctccccgggcgccggccgcgcctccgcccgc
cccaagccctacgacccccccgcggagaaggcggtggccgcgaaggtcaagggcgagaag
ctggataagaagctgaagaagatggagcagaacaagacggccgccaccaggtaccggcag
aagaagagggcggagcaggaggcgctcaccggcgagtgcaaggagctggagcagaagaac
gaggcgctgaaggagcgcgcggacgcgctggccaaggagatccagtacctgaaggatctg
atcgaggaggtccgccgggcgcggggccgccggagggccccatag

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