Equus caballus (horse): 100070426
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Entry
100070426 CDS
T01058
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00790
Folate biosynthesis
ecb01100
Metabolic pathways
ecb01240
Biosynthesis of cofactors
ecb01523
Antifolate resistance
ecb04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100070426 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100070426 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100070426 (FPGS)
Enzymes [BR:
ecb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100070426 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100070426
NCBI-ProteinID:
XP_023484720
Ensembl:
ENSECAG00000013074
VGNC:
18122
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Position
25:31793442..31802576
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AA seq
588 aa
AA seq
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MSRARSHLRSAFLLAAVSPLSATTRFGARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQTQLEAMELFLARSGLQLEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTNHFWRLYHRLQETKDGSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGLDHTSLLGDTVEKI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDHQGIGELKASQPSLQWQLPLAPVFQPTSHMQHGLRDTE
WPGRTQVLRRGPLTWYLDGAHTVSSVQACVRWFRQALRGRDRPDSGPEVRVLLFNSTGDR
DPAALLKLLQPCQFHYAVFCPNLTEVSPTGNEDQQNFTVTLDQVLLRCLTHQQHWSRLDK
EQASPNLWNSPGPEPGGPASLLLAPCLPHPVSTSSLVFSCISHALQWISQGRDPVFQPPS
PPRGLLAHPVAGSGASVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgcagccacttgcgctcggctttcctcctggctgcggtttctccgctc
agtgcaacgacccgcttcggcgcgcgacgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactcaacaccctccagaccaacgccagc
tacctggagcaggtgaagcgccagcggggtgaccctcagacacagctggaagccatggag
ctgttcttggcacgcagtgggctacagttggaggacttggaccagctgaacatcattcat
gtcaccgggaccaaggggaagggctccacctgtgccttcactgaacgaatcctccgaagc
tatggcttgaagaccggattctttagctctccccacctggtgcaggtgcgcgagcggatc
cgcatcaacgggcagcccatcagccctgagctcttcaccaaccacttctggcgcctctac
caccggctgcaggagaccaaggatggcagcagctgtgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacatcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcatcggtggggcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggggtctcctctcttggcctcgaccacaccagccttttgggggacacggtggagaagatt
gcatggcagaaagggggcatcttcaagcgtggtgtccctgccttcaccgtgcttcagcct
gacgggcccctggcagtgctgagggaccgtgcgcagcagatctcatgtcctctctacctg
tgcccacctctggaagccctggaggaaggggggccaccgctgacccttggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggcccgctgctggctgcagcaa
aaggaccaccagggcatcggggagctgaaggcatcccagccgagtctccagtggcagctg
cccctggcacccgtcttccagcccacgtcccacatgcagcacgggcttcgggacacggag
tggcctggccggacgcaggtgctgcggcgcgggccgctcacctggtacctggacggcgcg
cacaccgtcagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcgcggccgt
gacagaccggacagtgggcccgaggtgcgtgtcttgctcttcaactctactggggaccgg
gatcccgcggccctgctgaagctgttgcagccctgccagtttcactatgctgttttctgc
cccaacctgacagaggtgtcacccacgggtaacgaagaccagcagaacttcacagtgaca
ctggaccaggtgctgctccgctgcctcacacaccagcagcactggagccgcctggacaag
gagcaggccagcccgaacctctggaacagccccggcccggagcctggtgggcccgcgtcc
ttgctgctggcaccctgcctgccccaccccgtcagcaccagctcccttgtcttcagctgc
atctcccacgccttgcagtggatcagccaaggccgggaccctgtctttcagccacccagt
cccccacggggcctcctcgcccaccccgtggcaggcagcggggccagtgtactgcgggag
gctgctgccatccacgtgctggtcacaggcagcctgcacctggtcgggggtgtcctgaag
ctgctggagccctccctgtcccagtag
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integrated database retrieval system
