Equus caballus (horse): 100070655
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Entry
100070655 CDS
T01058
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00140
Steroid hormone biosynthesis
ecb01100
Metabolic pathways
ecb05215
Prostate cancer
Module
ecb_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100070655 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
100070655 (SRD5A2)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100070655 (SRD5A2)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
100070655
NCBI-ProteinID:
XP_001501572
Ensembl:
ENSECAG00000024330
VGNC:
23574
UniProt:
F6YAW2
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All DBs
Position
15:66000411..66047100
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AA seq
254 aa
AA seq
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MPVHCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESVMPAAIRLPARAAWFLQELPS
FAVPAGILARQPRSIFGQPATVLLGLFCAHYFHRTFVYSFLTRGRPFPVAFLFRGFVFCV
GNGLLQGYYLVYCAEYPAEWYTDLRFSVGVFLFLLGMGINIHSDYILRQLRKPGEIIYKI
PQGGLFTYVSGANFLGEIIEWSGYALASWSLPALAFAFFSLCFLGLRAFHHHRFYIKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcccgttcactgccagcagagcccggtgctggcaggcagcgccactttggccgccctg
ggggcgctggtcctgtacctcgcgaagccctccggctacgggaagtactcggagagcgtg
atgcccgcggctatccgcctgcccgcccgtgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagcctcgctctatcttcggccagcctgcg
actgtgcttctgggcctcttctgcgcacattactttcacaggacatttgtttactcattt
ctcactagagggaggccttttccagttgcattccttttcagaggctttgtcttctgcgtg
ggaaatggactcctccaaggctactacctggtttactgtgctgaatatcctgctgagtgg
tacacagacctacggtttagcgtgggtgtcttcttatttctcttgggaatgggaatcaac
attcatagtgactatatattgcggcagctcaggaagcctggagaaatcatctataaaatt
ccacaaggtggcttgttcacctatgtttcgggagccaatttccttggtgaaatcattgaa
tggagcggctatgcactggcctcttggtccctcccagcacttgcatttgcatttttctct
ctttgtttccttgggctgcgagcttttcaccaccataggttctacatcaagatgtttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa
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