Equus caballus (horse): 100071137
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Entry
100071137 CDS
T01058
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100071137 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ecb01002
]
100071137 (BACE1)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
100071137 (BACE1)
Peptidases and inhibitors [BR:
ecb01002
]
Aspartic peptidases
Family A1: pepsin family
100071137 (BACE1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
100071137
NCBI-ProteinID:
XP_023500649
Ensembl:
ENSECAG00000012427
VGNC:
15750
LinkDB
All DBs
Position
7:complement(25801990..25825394)
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AA seq
508 aa
AA seq
DB search
MAQVLPWLLLWVGSGVLPARCTQPGIRLPLRSGLGGAPLGLRLPRETDEEPEETGQRGSF
VDMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLILP
PFHRSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING
SNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG
SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT
NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT
NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI
GFAVSACHVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPL
CLMVCQWRCLRCLRHQHDDFADDISLLK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagtactgccctggctcctgctgtgggtgggctcgggagtgctgcctgcccgc
tgcacccagccgggcatccgactgcccctgcgaagcgggctggggggcgcccccctgggg
ctacggctgccccgggagactgacgaggagccggaggagaccggccagaggggcagcttt
gtggacatggtggacaacctgaggggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacaggcagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctaattctgcct
cctttccacaggtccagcacataccgggacctccggaagggcgtgtatgtgccctacacc
cagggcaagtgggagggggagctgggcaccgacctggtgagcatcccccatggccccaac
gtcactgtgcgtgccaacatcgctgccatcactgaatcagacaagttcttcatcaatggc
tccaactgggagggcatcttggggctggcctatgctgagatcgccaggcccgatgactcc
ttggagccattctttgactccctggtaaagcagacccacgttcccaacctcttctccctg
cagctctgtggtgctggcttccccctcaaccagtcagaagtgctggcctcggtcggaggg
agcatgatcattggggggattgaccactcactgtacacgggcagcctctggtacacaccc
atccggcgggagtggtattatgaggtgatcattgtacgggtggagatcaatggacaggat
ctgaaaatggactgcaaggagtacaactatgacaagagtatcgtggacagtggcaccacc
aaccttcgtttgcccaagaaagtgtttgaagctgctgtcaaatccatcaaggcagcctcc
tcgacggagaagttcccagacggtttttggcttggggaacagctggtgtgctggcaagca
ggcaccactccttggaacattttcccagtcatctcactctacctgatgggggaggtcacc
aatcagtccttccgcatcaccatccttccacagcaatacctgcggccagtagaagacgtg
gccacgtcccaagacgactgttacaagttcgccatctcacagtcatccacgggcactgtt
atgggagctgttatcatggagggcttctacgttgtctttgatcgggcccgaaaacgaatt
ggctttgctgtcagtgcttgccacgtgcacgatgagtttaggacggcagcggtggaaggc
ccttttgtcaccccggacatggaagactgtggctacaacattccacagacagatgaatca
accctcatgaccatagcctatgtcatggctgccatctgcgccctcttcatgctgccactc
tgcctcatggtgtgtcagtggcgctgcctccgctgcctgcgccatcagcacgatgacttt
gctgatgacatctccctgttgaagtga
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