Equus caballus (horse): 100071472
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Entry
100071472 CDS
T01058
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00061
Fatty acid biosynthesis
ecb00620
Pyruvate metabolism
ecb00640
Propanoate metabolism
ecb01100
Metabolic pathways
ecb01212
Fatty acid metabolism
ecb04152
AMPK signaling pathway
ecb04910
Insulin signaling pathway
ecb04922
Glucagon signaling pathway
ecb04936
Alcoholic liver disease
Module
ecb_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100071472 (ACACA)
00640 Propanoate metabolism
100071472 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100071472 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100071472 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100071472 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100071472 (ACACA)
04922 Glucagon signaling pathway
100071472 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100071472 (ACACA)
Enzymes [BR:
ecb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100071472 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100071472 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100071472 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100071472
NCBI-ProteinID:
XP_023508732
Ensembl:
ENSECAG00000010631
VGNC:
14961
LinkDB
All DBs
Position
11:complement(36602975..36874885)
Genome browser
AA seq
2396 aa
AA seq
DB search
MWWSTLMSILRASSFWRWISAQTERIIRALRAHFDRIMDEPSPLARLALELNQHSRFIIG
SVSEDNSEDEISSLVKLDLLEEKEGSLSPASVGSDALSDLGISSLQDGLALHMRSSMSGL
HIVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSY
EMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPV
QAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSG
SGLRVDWQENDFTKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIR
KVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQR
RHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRL
QVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGLSPWGDAPIDFENSAHVPCAR
GHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFS
WGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQ
AERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYV
LKVTRQSPNSYVVVMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKT
CVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYV
KRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIHSTALRGEKLHRVFHYVLDNLVN
VMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEM
AQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGH
MKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVT
MLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVES
IFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYE
LNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLL
DNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPR
NEPIHILNVAIKTDGDIEDDRLAAMFREFTQQKKSTLVEHGIRRLTFLVAQKDFRKQVNY
EVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMH
LYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFN
NTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPT
GKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDL
LQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTHAFLPSPPLPSDMLTYTELVLDDQ
GQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRA
SELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVS
ALNSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRSSGMIAGESSLAYDEIITISLVTC
RAIGIGAYLVRLGQRTIQVENSHLILTGAAALNKVLGREVYTSNNQLGGIQIMHNNGVTH
SKVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRP
HPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPA
NLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLK
FGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSILEPEG
TVEIKFRRKDLVKTMRRVDPVYIHLAERLGKGGGHVGSPWQGTPELSAAERKELENKLKE
REEFLIPIYHQVAVQFADLHDTPGRMQEKGIINDILDWKTSRTFFYWRLRRLLLEDLVKK
KIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEE
NIKYISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7191 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcagacagaaagaattataagagctctgagagctcattttgatagaataatggatgaa
ccatcccccttggccagacttgctctggagctgaaccagcactcccgattcataattggt
tccgtgtctgaagataactcagaggatgagatcagcagcctggtaaagttggacctgctg
gaggagaaggagggctctctgtcaccagcttctgttggctcagatgccctctctgatttg
gggatctctagcctacaggatggcttggccttacacatgaggtccagcatgtctggctta
cacatcgtaaagcaaggtcgagaccggaagaaaatagactcacagcgagatttcactgta
gcttctccagcagaattcgttactcgttttggggggaataaagtgattgagaaggttctt
attgccaacaatggcattgcagcagtgaaatgcatgcgatctatccgtcggtggtcttat
gagatgtttcgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaagacctt
aaagccaacgcagaatacattaagatggcagatcactatgtcccagtgcctggaggacca
aacaacaacaactatgcaaatgtggagttaattcttgatattgctaaaaggatcccagta
caagcagtgtgggctggctggggtcatgcttctgagaatcccaaactcccagaactactt
ttgaaaaatggcattgccttcatgggtcctccaagccaggccatgtgggctttaggggat
aagattgcatcttccatagtggctcaaactgcaggtatcccaactcttccctggagtggc
agtggtcttcgtgtggactggcaggaaaatgattttacaaaacgtatcttgaatgttccc
caggaattatatgaaaaaggttatgtgaaggatgtggatgatgggctaaaggcagcagag
gaagttggatatccggtaatgatcaaggcctcagaaggcgggggagggaagggaatcaga
aaagtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtccct
ggatctcctatatttgtgatgagactagccaaacaatctcgtcatctggaggtacagatc
ttagcagatcagtatggcaatgcaatctctttgtttggtcgtgattgctctgtacagcgc
aggcatcagaagattattgaagaggcacctgctgctattgctactccagcagtatttgaa
catatggaacagtgtgctgtgaaacttgccaaaatggttggttatgtgagtgctgggact
gtggaatacctctacagccaggatggcagcttctactttctggaactgaaccctcggcta
caggtagagcacccttgtacagagatggtggctgatgtcaacctccctgcagcacaactc
cagattgccatgggaatccctctatacagaatcaaggatatccgtatgatgtatgggtta
tctccctggggtgatgctcccattgattttgaaaattctgctcacgttccttgcgcaagg
ggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagc
tcaggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttatttcagt
gttgctgctgcaggaggacttcatgaatttgctgattctcagtttggtcactgcttttcc
tggggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggagctgtct
attcggggtgactttcgaactacagttgaatatctgatcaaattgttggagactgaaagc
tttcagttgaatagaattgacactggctggttggacagactgatagcggaaaaagtacag
gcagagcggcctgacaccatgctgggcgttgtgtgtggggctctccacgtggcagatgtg
agcctgcggaatagcatctctaacttccttcactccttagaaaggggtcaagtccttcct
gctcatacccttctgaatacagtagatgttgaacttatctatgaaggagtcaagtatgtg
cttaaggtgactcgacagtcccccaactcctatgtagtggtcatgaacggctcgtgtgta
gaagtagatgtacatcggctgagtgatggaggactgctcctgtcctatgatggcagcagt
tataccacgtacatgaaggaggaagtggatagatatcgcatcacgattggcaataaaaca
tgtgtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctgggaagttg
atccagtacattgtggaggatggaggccatgtgtttgctggccagtgctatgctgagatt
gaggtgatgaagatggtaatgaccttaacagctgcagagtctggctgtatccattatgtc
aaaaggcctggagcagctcttgaccctggttgtgtaatagccaaaatgcagttggacaac
cccagcaaggtccagcaggctgagcttcacacgggtagtctgccacggatccacagcaca
gcactcagaggcgagaagctccatcgagtgttccactatgtcctggataatctggtcaac
gtaatgaatggatactgccttccagatcctttttttagcagcagggtaaaagactgggta
gagcggttgatgaagaccctcagagatccctccttgcctctcctagaattgcaagatatc
atgaccagtgtctctggccgtatccccccgaatgtggagaagtctatcaagaaggaaatg
gctcagtatgctagcaacatcacatctgtcctctgtcagtttcccagccagcagattgcc
aacatcctagatagtcatgcagctacactgaaccggaaatctgagcgggaagtcttcttc
atgaacactcagagcattgtccaactggtgcagaggtaccgaagtggcatccgaggccac
atgaaggctgtggtgatggatctgctgcgacagtacctgcgagtggagacacaattccag
aatggtcactatgacaaatgtgtgtttgcccttcgggaggagaacaagagtgacatgaac
actgtactgaattatatcttctctcacgctcaagtcaccaagaagaatcttctggtcaca
atgcttattgatcaactgtgtggccgggaccctactctcactgatgagctgctgaatatc
ctcacagagctaactcaactcagtaagaccaccaatgccaaagtggcacttcgagcacgc
caggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagtagagtct
atcttcctatcagctattgacatgtatggacatcagttttgcattgagaacttgcagaaa
ctcatcttgtctgaaacatctatttttgatgtccttccaaacttcttctatcacagcaac
caggtagtaaggatggcagctctagaggtgtatgttcgaagggcttatattgcctatgaa
cttaacagtgtacaacaccgccagcttaaggacaacacctgcgtggtggaattccagttc
atgctgcccacatctcatccaaacagagggaacatccccacgctaaacagaatgtccttc
tcctccaacctcaaccactatggcatgactcatgtagctagtgtcagcgatgtgctattg
gacaactccttcacgccaccatgtcagaggatgggcggaatggtctcttttcggactttt
gaagattttgtcaggatctttgatgaagtgatgggctgcttctgcgattccccacctcaa
agccccacattccctgaggcaggtcacacatctctgtacgatgaagacaaggtccccagg
aatgaaccaattcatattctgaatgtggctatcaagactgatggtgatattgaggatgat
aggctggcagctatgttcagagagtttacccagcaaaagaaatctaccctggttgagcat
gggatccggcgccttacgttcctggttgcgcaaaaggatttcagaaaacaggtcaactat
gaggtggatcagagatttcatagagagttccctaaatttttcacgttccgagcaagggat
aagtttgaggaggatcgtatctatcgtcacctggagcctgccctagctttccagttggag
ctaaaccgcatgagaaattttgaccttactgccattccatgtgctaatcacaagatgcac
ctgtatcttggggcagccaaggtggaagtgggcacagaagtgacagactacaggttcttt
gttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaatatcta
caaaatgaaggggagcggctactcctcgaagccatggatgagttggaagtcgcttttaac
aatacaaatgtccgtactgactgcaaccacatctttctcaactttgtccccacggtcatc
atggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatggaagtcgg
ctgtggaaattacgcgtcctccaggcagaactgaaaatcaacattcgcctgacaccaact
ggaaaagcaattcccattcgcctcttccttacaaacgagtctggctattacttggacatc
agcctgtacaaggaagtgactgactccaggacagcacagatcatgttccaggcctatgga
gacaaacagggaccattgcatggaatgttaatcaacactccatatgtgaccaaagacctg
cttcaatcaaagagattccaggcacagtccttagggacaacatacatatatgatatccca
gagatgtttcggcagtccctgatcaaactctgggagtctatgtccactcatgcattcctt
ccatcgccccctctgccgtctgacatgctgacgtatactgagctcgtactggacgatcaa
ggtcaactggtccacatgaacaggctgccgggaggaaatgagattggcatggtagcttgg
aaaatgacccttaaaagtcctgaatatccagaaggccgagatatcattgttattggcaat
gatatcacataccgaattgggtcctttgggccccaggaggatttgctgtttctcagagct
tctgagcttgccagagcagagggcatcccccgcatcttcgtagcagctaacagtggagca
agaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagatcctgag
gatccttacaagggatacaaatatttatatctgacccctcaagattataagagagtcagt
gctctcaactctgtgcattgtgaacatgtggaggatgaaggagaatccaggtacaagata
accgatattattgggaaagaagagggacttggagtagagaaccttcgaagttctggaatg
attgcaggagaatcctcattggcctatgatgagatcatcaccatcagcctggttacgtgc
cgggccattgggattggggcttaccttgtccggctgggacagagaaccatccaggttgaa
aactctcacttaattctgacaggagctgccgccctcaacaaagtccttgggcgggaagta
tatacctccaataaccagctcggaggcatccagatcatgcacaacaatggagtgacccac
agcaaagtttgtgatgactttgaaggggttttcactgtcctgcactggctgtcttacatg
cctaagagtgtgcacagttcagttcctctcctgaactccaaggatcctatagacagaatc
atcgagtttgttcccacaaaggccccatatgatcctcgatggatgctagcaggccgtcct
cacccaacccagaaaggtcagtggttgagtggattttttgactatggatctttctcagag
atcatgcaaccctgggcacagaccgtagtggttggcagagccaggctaggaggaatacct
gtgggagtagttgccgtggaaacccgaacagtggaactaagtatcccagctgatcctgca
aacctggattctgaagccaagatcatccaacaagctggccaggtttggttcccagactct
gcctttaagacctatcaggctatcaaggacttcaaccgtgaagggctgcctctgatggtc
tttgccaactggagaggcttctctggtggaatgaaagatatgtatgaccaagtgctgaag
tttggtgcttacatcgtggatggcttacgggagtgctctcagcctgtgatggtttacatt
cctccccaggccgagcttcggggtggctcctgggtggtgattgaccccaccatcaacccc
cggcacatggagatgtatgctgaccgagaaagcaggggctcaattttggagccagaaggg
acagtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggacccg
gtctacatccacttggctgagcgattggggaaaggaggaggacacgttggctccccatgg
caaggcaccccagagctaagtgcagctgagcggaaggagctggagaacaagttgaaggag
cgagaggaattcctgattcccatttaccatcaggtagctgtgcagtttgctgacttgcac
gacacaccaggccggatgcaggagaagggtattattaatgacatcctggattggaaaaca
tcccgtaccttcttctactggcggctgaggcgtctcctgttggaggacctggtcaagaag
aaaatccacaatgccaaccctgagctgactgatggccagatccaggccatgttaaggcgc
tggtttgtggaagtggaagggacagtgaaggcctacgtttgggacaataacaaggatctg
gtggagtggctggagaaacagctaacagaggaagatggtgttcgctcagtaatagaggaa
aacatcaaatatatcagcagagactatgtcctcaagcagatccgcagcttggtacaggcc
aatccagaggttgccatggattcgatcatccatatgacccagcacatctcacccactcag
agagcagaagttgtacggatcctctccacgatggactccccttcgacgtag
DBGET
integrated database retrieval system