Equus caballus (horse): 100071503
Help
Entry
100071503 CDS
T01058
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X2
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
ecb
Equus caballus (horse)
Pathway
ecb04270
Vascular smooth muscle contraction
ecb04360
Axon guidance
ecb04611
Platelet activation
ecb04625
C-type lectin receptor signaling pathway
ecb04810
Regulation of actin cytoskeleton
ecb05135
Yersinia infection
ecb05152
Tuberculosis
ecb05163
Human cytomegalovirus infection
ecb05200
Pathways in cancer
ecb05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100071503 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100071503 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
100071503 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100071503 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
100071503 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100071503 (ARHGEF12)
05205 Proteoglycans in cancer
100071503 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100071503 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
100071503 (ARHGEF12)
05152 Tuberculosis
100071503 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ecb04131
]
100071503 (ARHGEF12)
Membrane trafficking [BR:
ecb04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
100071503 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
100071503
NCBI-ProteinID:
XP_005611701
Ensembl:
ENSECAG00000022702
VGNC:
15484
LinkDB
All DBs
Position
7:28569423..28709961
Genome browser
AA seq
1544 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTSSKPLGDALTVSEVEADPGDGLGRIDYSSGDVS
RHSSDNADSPKSGLKERIYLEENPEKSEVNQDIDTQSLIGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLDKRRPELIPEDLHRHYIQTMQEKVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSGLASEGADAGY
LPANSTSSVVSGATLSQEGGKENDTGSKQVGETPTSGDSLDGTPRTPNTIFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKSVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLDDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTR
PIPLPESPPCEGDNDEEEPPKLKVEHHGISVTGLQSPDRDLGLESPLISSKPQSHSLGAS
GKSEVDDLFVAERQFAKEQRADGTLKEVGGNYQITIPNPHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWPHFPRYRTASPGAQADSGTQNSETLKAYHPGEGQMPFRTGTG
DISSCYGPRTSTESSAPQDSVVLAFQDGQASNILVMDHVIMTPEMPPAEPEGGLDESGEH
FFDAREAHSDDNPSDGDGAVKKEEKDVNLRISGNYLILDGYETVQESSTDEEIASSLPSQ
PVTGIPSVDCTHQRQHSPQNARSDGAVSPFTPEFLVQQRWGAMEDSCFEIQSPPSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
NT seq
4635 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctaccatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaatcgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcaacgttgtgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaaccatctggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgctgattctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatccccacattcacctgga
gcatctgggaatatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgaggaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttacgtcctccaagcctttaggtgatgccctgacagtcagtgag
gtagaagcagatcctggtgacggactaggcagaattgattatagcagtggagatgtttct
cggcacagtagtgacaatgcagatagtcccaagagtggcctgaaagagaggatttatcta
gaggaaaacccagagaaaagtgaagtaaatcaggacattgatactcaatcactgattggg
agtccctcaacccgtatagcacctcatattattggagcagaggatgatgattttggtact
gaacatgaacagatcaatgggcaatgtagctgtttccagagcattgaactgctaaaatct
cgccctgctcacttggctgttttcttacaccatgtggtttcacagtttgaccctgcaaca
ttgctctgttatctctactcagacctgtataaacagaccaattccaaggagactcgtcgt
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtt
cctgatgaaatatcagtagatctagacaaaagaagacctgagcttattcctgaggatcta
catcgccactatatccaaactatgcaagaaaaagtccatccagaagttcagaggcacttg
gaagattttcggcagaaacgtagcatggggctgaccttggctgaaagtgaactgactaaa
cttgatgcagagcgagacaaggaccgggtaactttggagaaggaacgggcatgtgcagag
cagattgttgccaaaattgaagaagtgctgatgactgctcaggctgtagaagaagataag
agttcaacaatgcagtatgttattctcatgtacatgaagcatttgggagtaaaagtgaaa
gaacctcgaaatttggagcacaagcggggtcggattggattccttccaaaaatcaagcaa
agtatgaagaaagatagggaaggcgaagaaaaagggaagcgaagaggattccctagcatc
ctgggacctccgaggagaccaagccgtcatgacaacagtgcaattggcagagccatggaa
ctacagaagcagcgccaccctaagcacttatccacaccctcatccgtgagtcctgaacct
caagaccctgctaagttgcgccagagtggcttagcaagtgaaggagcagacgctggatac
ctgccagccaattccacgtcgtctgtggtttcaggggccactctttcccaggaaggaggg
aaagaaaatgatactggatcaaaacaagttggagaaacccccacatctggagactcctta
gacggcacacctcgtactcccaataccatctttgatttcccacctcctccattagaccaa
gtgcaggaggaggaatgggaagtagaaagggtgactgaacacgggacaccaaagcccttt
cgaaagtttgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagatccacccaactggcaacagctcgttagtcgggaagtgttactggga
ctaaagccttgtgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgttcgaacgctgaaggttcttgatcaggtcttttatcagcgagtgtccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttggaagatattcttcag
cttcacattggattgaatgagcaaatgaagtctgttcgaaagaggaatgaaacttctgtt
attgatcagattggggaagatttgctgacctggttcagcggaccaggggaggagaagttg
aaacacgctgctgctaccttttgcagtaaccaaccttttgccctggaaatgatcaagtct
cgtcagaaaaaggattctagattccagacttttgtgcaagatgctgagagtaatccactg
tgtcgtcgtctacagctcaaggatatcattcccacccaaatgcagaggcttactaagtac
cctcttctattggataatattgccaaatacacagaatggccaatggaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaattatgtaaatcaggctgtcaaggag
gcagaaaacaagcagcgcttagaagattatcagcgtcgccttgatacctcgaatctgaag
ttgtcagagtacccaaatgttgaagaactcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtttggaaggtgaatagagataaaactattgatctatacact
ttgctgctggacgacattcttgtattgttgcaaaagcaggatgataggctggtattaagg
tgtcatagtaagattctggcatctacagctgatagcaaacacacgtttagccctgtcatt
aagttgaatacagtgttggttcgacaagtggccacagataacaaagctttattcgtcatc
tccatgtcagacaatggagcccaaatttatgagctggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcggatggctgcatcagtgaaggagcaatccacaagg
ccaattccactgccagagtcgcccccttgcgaaggagacaatgatgaagaagaacctcca
aaactaaaagtagaacatcatggcatttcagtcactggtctgcagagtccagacagagat
ttgggattagagtctcccttaatatcgtcaaaacctcaatctcattcactgggtgcttct
gggaaatcagaggtagatgatctctttgtggctgagagacagtttgcaaaggagcaacgt
gcagatggaactctaaaggaagttggaggaaattatcaaatcacaatcccaaatccacac
ttgcctgtctcagaagaacggtgggcattggatgcactaaggaatttgggtttgttgaag
cagttgctggtacaacagctgggtttgactgagaagagcactcaggaagactggccacat
ttcccaagatacaggacagcctctccaggggcacaggcagacagtggaacccagaactct
gaaactctcaaggcctatcatcctggtgaaggacagatgccctttagaactggaactggt
gacatttcatcttgttacggtccacggacttcaactgaatcttctgctccacaggattca
gtggtactggctttccaagatggccaggcaagtaacattttagtaatggaccacgtgatt
atgaccccagagatgcctcctgcagagccagaagggggtcttgatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataatccatcagacggtgatggagcagtt
aaaaaggaagagaaggatgttaatttgcgcatctcaggaaactatttgatccttgacggc
tatgaaacagtgcaggagagctccacagatgaggagattgcttcctcgcttccctcgcaa
cccgtgacaggcatcccctctgtggactgtacgcaccagcggcaacattctccccagaat
gctcgttctgatggggcagtttcaccgttcaccccagaattcctggtccagcagcgctgg
ggggctatggaggattcctgttttgagatccagagtcccccgtcttgtgcagattcacaa
agccagatcatggagtacattcataagatagaggctgaccttgaacacttaaagaaggtg
gaggaaagttacaccattctttgccaaaggctggctggatcggccctcacagataagcac
tcagataaaagttag
DBGET
integrated database retrieval system
