KEGG   Equus caballus (horse): 100072047
Entry
100072047         CDS       T01058                                 
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
  KO
K14613  MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
ecb  Equus caballus (horse)
Pathway
ecb01523  Antifolate resistance
ecb04977  Vitamin digestion and absorption
ecb04978  Mineral absorption
ecb04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    100072047 (SLC46A1)
   04981 Folate transport and metabolism
    100072047 (SLC46A1)
   04978 Mineral absorption
    100072047 (SLC46A1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100072047 (SLC46A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecb02000]
    100072047 (SLC46A1)
Transporters [BR:ecb02000]
 Solute carrier family (SLC)
  SLC46: Folate transporter
   100072047 (SLC46A1)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
    100072047 (SLC46A1)
SSDB
Motif
Pfam: MFS_1 Sugar_tr
Other DBs
NCBI-GeneID: 100072047
NCBI-ProteinID: XP_001504178
Ensembl: ENSECAG00000006826
VGNC: 23227
UniProt: F6UGY6
LinkDB
Position
11:complement(42706294..42712668)
AA seq 459 aa
MEGRASPLGEPRARPAGAVLYRGPVEPLVFLANFALVLQGPLTTQYLWHRFSADLGYNGT
RDRGNCGNHSGDPVMQEVETLTSHWTLYTNVCGFLVGLFSSTLLGAWSDCVGRRPLLVLA
SFGLLLQALVSIFVVQLQLHVGYFVLGRILCALLGDFSGLLAAGFASVADVSSNRNRTIR
MALLEACIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAMTLYAAFCFGETVKEPTRA
RLFTLRHHRSIVQLYVTPAPEKSRKHLALYSLAIFVVITVHFGAQDILTLYELSTPLCWD
SRLIGYGSAAQHLPYLTSLLVLRLLQYCLADTWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVTTPVIRAKLSKMVLHSEHGALFSAVACVNALAMLTASGIFNSLYPATLNF
MKGFPFLLGAALLFIPAILIGMLEKATPHPEFQQFPQSP
NT seq 1380 nt   +upstreamnt  +downstreamnt
atggaggggcgcgcgagcccactgggcgagccccgcgcccggcccgcgggggccgtgctg
taccgaggccccgtggagccgctcgtcttccttgccaacttcgccttggtcctgcagggc
ccgctcaccacacagtacctgtggcaccgcttcagtgccgaccttggttacaatggcacc
cgcgacaggggcaactgtggcaaccacagcggggaccccgtcatgcaggaagtggagacc
cttacctcccactggaccctctacacgaacgtgtgcggcttcctggtggggctcttctcg
tccaccctgctgggcgcctggagtgactgtgtgggccgccgcccgctgctggtgctggcc
tcgtttggcctgctgctccaggccttggtgtccatctttgtggtgcagctgcagcttcat
gtcggctacttcgttctgggccgcatcctttgtgctcttctcggtgacttcagtggcctt
ctggctgctggctttgcctctgtggcagatgtcagctccaaccgcaaccgcaccatccga
atggccctgctggaagcatgcatcggggtggcagggatgctggccagcctccttgggggc
cactggctccgggcccagggttatgccaacccgttctggctggccttggccttgctgata
gccatgactctctacgcagcattctgctttggtgagacggtgaaggagccgacacgtgct
cggctcttcacgctccgtcaccaccgatccattgtccagctctacgtgactccagctccg
gagaagtccaggaaacatttagccctgtactcattggccatcttcgtggtgatcactgtg
cactttggggcccaggacatcctgaccctctatgaactgagcacacccctctgctgggac
tccaggctgatcggctatggttctgcggctcagcacctcccgtacctcaccagcctgctg
gtcctgcggcttctgcagtactgcctggctgacacctgggtggctgagatcggcctggcc
ttcaacatcctggggatggtggtctttgcatttgctaccatcacacccctcatgttcaca
gggtacgggctgctcttcctgtcgttagtcaccacacctgtcatccgggccaagctctct
aagatggtgctccactcagagcatggtgctctcttttctgctgtggcctgtgtgaatgca
ttggccatgctgacggcctctggcatcttcaactcgctctacccagccactctgaacttc
atgaagggcttccccttcctcctgggagctgccctcctcttcatcccagccattctgatt
gggatgctggaaaaggctactcctcaccctgaattccagcagtttccccagagcccctga

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