Equus caballus (horse): 100072395
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Entry
100072395 CDS
T01058
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
ecb04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100072395 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
100072395 (PDE5A)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
100072395 (PDE5A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
100072395
NCBI-ProteinID:
XP_001502355
Ensembl:
ENSECAG00000013957
VGNC:
21247
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Position
2:108413278..108542926
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AA seq
865 aa
AA seq
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MERAGLGSAPPPQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFADRVHTIPVCKE
GIRGHPESCSCSLQQTPRADSSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEK
KEQMPLTPPKFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLIAADRYSLFLV
CEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVTNTMEALNIPDVSKD
KRFPWTNENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPNMQVGFIDAICLQLYEALTHVSKDCFPLLDGCRKNR
QKWQALAEQQEKMLINGESSQAKRN
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggccggcctcggctctgcgccgccgccgcagcagcgggaccaggactcagtg
gaagcctggctggacgatcactgggactttaccttctcttactttgttaggaaagccacc
agagagatggtcaatgcatggtttgctgacagagttcataccatccctgtctgcaaggaa
ggcatcagaggccacccggaatcctgctcttgctccttgcagcagactccccgagcagat
agcagcgcccctgggacaccaaccaggaaaatctctgcctccgaatttgaccggcctctt
agacccattgttgtcaaggattctgagggaactgtgagcttcctctctgactcagaaaag
aaggaacagatgcctctaacccctccaaagtttgataatgatgaaggggaccagtgctca
agactcttggaattagtgaaagatatttctagtcatttggatgtcacagccttatgtcac
aaaattttcttgcacatccatggactcattgccgctgaccgctattccctgttcctcgtc
tgtgaggacagctccaacgacaagtttcttatcagccgcctctttgatgttgcagaaggt
tcaacactggaagaagcttccaataactgtatccgcttagaatggaacaaaggcattgtg
ggtcatgtggcagcgcttggtgagcctttgaacatcaaagatgcgtatgaggatcctcga
ttcaatgcagaagttgaccaaattacaggctacaagacacaaagtattctttgtatgcca
ataaagaatcatagggaagaggttgttggcgtagcccaggccatcaacaagaaatcgggt
aatggtgggacattcactgaaaaggatgaaaaggactttgccgcgtatttggcgttttgt
ggtattgttcttcataatgctcaactctatgaaacttcactgttggagaacaagagaaat
caggtgctgcttgaccttgctagcttaatttttgaagaacaacaatcactagaagtaatt
ctaaagaagatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattccttttctagtgtgtttcacatggagtgtgaggaa
ttagaaaaatcatcagatactttaacaagggaacgtgatgccaacagaatcaattacatg
tatgctcagtatgtgacaaatactatggaagcacttaatatcccagatgtcagcaaggac
aaaagatttccctggacgaatgaaaacacaggaaatgtaaaccagcagtgcattagaagt
ttgctttgcacgcctataaaaaatggaaagaagaataaagtgataggggtttgccaactt
gttaataagatggaggagaatactggcaaggttaagcctttcaaccgaaatgatgaacag
tttctggaagcttttgtcatcttttgcggcttggggatccagaacacacagatgtatgaa
gcagtggagagagccatggccaagcagatggtcacattagaggttctgtcgtatcatgca
tcagccgcggaggaagaaacaagagagctccaatccttagcggctgctgtggtaccatct
gcccagacccttaaaattactgacttcagcttcagtgactttgagctgtctgacctggaa
acggcactgtgcacaattcggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcagatggattttgagtgttaagaagaattaccggaagaacgtt
gcctaccataattggaggcatgcctttaatacggcccagtgcatgtttgctgctctaaag
gcaggcaaaattcagaacaagctgactgacctggagatacttgcgttgctgattgccgca
ctgagccacgatctggatcaccgtggggtgaataactcttatatacagcgaagtgaacac
ccacttgctcagctctactgccattcaatcatggagcatcatcattttgaccagtgcctg
atgattcttaacagtccaggcaatcagattctcagtggcctctccattgaagaatataag
accacgttgaaaataatcaagcaagctattttagctacagacctagcactgtacattaag
aggcgaggagaattttttgaacttataagaaaaaatcaattcaatttggaagatcctcat
caaaaggagttgtttttagcgatgctgatgacagcttgtgatctttctgcaattacaaaa
ccctggcctattcaacaacggatagcagaacttgtagcgactgaattttttgaccaaggg
gacagggagagaaaagagctcaacatagagcccgctgatctaatgaacagggagaagaaa
aacaaaatcccaaatatgcaagttgggttcatagatgccatctgcttacaactgtatgag
gccctgacccatgtatcaaaggactgtttccctttgctagatggttgcagaaagaacagg
caaaaatggcaggctcttgcagaacaacaggagaagatgctgattaatggggaaagcagc
caggccaagcggaactga
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