KEGG   Equus caballus (horse): 100073094
Entry
100073094         CDS       T01058                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04012  ErbB signaling pathway
ecb04620  Toll-like receptor signaling pathway
ecb04664  Fc epsilon RI signaling pathway
ecb04668  TNF signaling pathway
ecb04912  GnRH signaling pathway
ecb04926  Relaxin signaling pathway
ecb04935  Growth hormone synthesis, secretion and action
ecb04936  Alcoholic liver disease
ecb05132  Salmonella infection
ecb05135  Yersinia infection
ecb05142  Chagas disease
ecb05161  Hepatitis B
ecb05166  Human T-cell leukemia virus 1 infection
ecb05167  Kaposi sarcoma-associated herpesvirus infection
ecb05169  Epstein-Barr virus infection
ecb05208  Chemical carcinogenesis - reactive oxygen species
ecb05417  Lipid and atherosclerosis
ecb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100073094 (MAP2K4)
   04012 ErbB signaling pathway
    100073094 (MAP2K4)
   04668 TNF signaling pathway
    100073094 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100073094 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    100073094 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100073094 (MAP2K4)
   04926 Relaxin signaling pathway
    100073094 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    100073094 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    100073094 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100073094 (MAP2K4)
   05161 Hepatitis B
    100073094 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100073094 (MAP2K4)
   05169 Epstein-Barr virus infection
    100073094 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100073094 (MAP2K4)
   05135 Yersinia infection
    100073094 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100073094 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100073094 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    100073094 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100073094 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100073094 (MAP2K4)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100073094 (MAP2K4)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: STE group
  STE7 family
   100073094 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 100073094
NCBI-ProteinID: XP_023509295
Ensembl: ENSECAG00000025163
VGNC: 19927
UniProt: A0A9L0S1M1
LinkDB
Position
11:54691894..54828149
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPAGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggtcccgcagggtccccggcgccgggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaa
aacccacacatagagagactgagaacacacagcattgaatcgtcaggaaaactgaagatc
tcccctgaacaacactgggatttcactgcagaggacttgaaagaccttggagaaattgga
cgaggagcttatggttccgtcaacaaaatggtccacaaaccaagtgggcaaataatggca
gttaaaagaattcggtcaacagtggatgaaaaagaacaaaaacaacttctcatggatttg
gatgtagtaatgcggagtagtgattgcccatacattgttcaattttatggtgcactcttc
agagagggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaggctctaaaccacttaaaggaaaacttgaaaatcattcacagagat
atcaaaccttccaatattcttctggacagaagtggaaatattaaactctgtgactttggc
atcagtggacagcttgtggactccattgccaagacaagagatgctgggtgtagaccatac
atggcacctgaaagaatagacccaagtgcgtcgcgacaaggatatgatgtccgctctgac
gtctggagtttggggatcacattgtacgagttggccacgggccgatttccttatccaaag
tggaatagtgtatttgatcaactaacacaagtcgtaaaaggagatcctccacagctgagc
aattctgaggaaagagaattctccccaagtttcatcaactttgtcaacttgtgccttaca
aaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatg
tatgaagaacgtaccgtagaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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