Equus caballus (horse): 102148544 Help Entry 102148544         CDS       T01058                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism ecb  Equus caballus (horse) Pathway ecb04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ecb00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     102148544 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ecb03036]     102148544 (SYNE2) Chromosome and associated proteins [BR:ecb03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     102148544 (SYNE2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH Motif Other DBs NCBI-GeneID:  102148544 NCBI-ProteinID:  XP_023483646 UniProt:  A0A3Q2ICF5 LinkDB All DBs Position 24:10579283..10875981 Genome browser AA seq 6915 aa AA seqDB search MASTPVLPAEDEQVSLGIDDLHISLQAKQEDTQKKTFTCWINSQLAKHTPPSVISDLFTD IRKGHVLLDLLEVLSGQQLPRDKGSNPFQCRINIEHALTFLQSRSIKLINIHITDIIDGK PSIILGLIWTIILHFHIEELAQTLPCNYDQPSPDSMSVVDSSPTSSPPAKKCSKAQERWQ MSAKNALLLWAQEQCATYESVSVTDFKSSWRNGMAFLAIIHALRPNLIDMKSVKHRSNKD NLKEAFRIAEQELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLQYSKKAPGTGDKAQGKMK DAMVWLTLQEKKLQKTLKDSEKETFFKKYESLLSFLESFNEEKKPFLDILSVKRNPDELN EDQLQMKEAWDGLNHQINVWKMKLNDDLPLPLHQIEAWLHEVEELIDEDLPAFQDYSEAM ALIQEKITLFKSLMDKSDCHSNTLLAFENRDEKHLPLVPPNKLEEMKRRINNISGKKFIP LLEFHYYKCSVLGLLDEVKSKLDVWNSKYGSKESVEFLLEDWRKFIEEKEFLAQLETSFQ KCGEIHKNLAGEYQNISEEYAMVESNVCMSRKNIYDVKSTLQEVLASWAAYAEKLRSLKA CFVETKKEQVTEVPFETLSQWNLEHTTLNEVGNFLIQVSYDEVGSSISKELRRLNKRWRK FITKTQLEMNLPLIKKQDQPILDNSGNIQLPKEEKPTVDFSADISIELPENHNQNMKAEE ESEKENEGFTEQLKVAEEVEKLIGQVEVWEAETKSVLDLLRHQDDVDTSMEESLQHLIAK GSMYEELVSRTEDTLQMDVQNVSSQESLQHVLTAGLQAKIQEAKEKVQINVVKLVAVLKN STDVSPELDVRLKMEELQKELESYITRAEQLLAQRESRSGLISKYKEALIIFNTKSLAKY LKAVEELKTNVTEDVKLSLEEKSGDVCAKWESLHHEMALYIQQLKIDIEKGKLSDNISKL EKQITKEKKLIRRGRTKGLIKEHEACFSEEGSLYQLDHHMNVLRELCEELTSQKSQQEMR RVLKDYEQKIERLRKCASEIHMTLQPTVGGTSKNKGTTNTSENGGRNAHSEVPSAESDDQ PSTEKAMDSVKNFTPESELNPPQEESIMEKHGKDHSASTNSLLQRYETHRETLELHLQNS KFRITSDFSSDRDRSSTCLQEKLTDLQVLKNETDACWKEFEITSLKLEELESDVQKPFII KTRDSLKEKERELQMSLNTRMESLETALQIVVPVEKESLLLCGSDLLLREMAIQEFHLSD ADGIYQHLGTIQDSIAKQIEICNNLEQSCNSALKELHPLDLHVTQNIILEHRTQLEEMNH KVQRSQDALKVLEDFLASLRTAELSPELVTDLSASETQVEPESTLTVGKKEGEIQVMKDK ARHLDECLKMLNISFKDAEQGEDSSCEKLLDALSKNVFEKGGYGTQEELTEEDKLLETCI FKNNELRKNIQDVHDQISKIGLKDPTVPAVKQRKKSLIRLDKDLDEYEEEKKHLQQVANS LPQFKDGREKALSQQCQETALLWENAKASVTECLDQCERVLELLKQYQSFKSVLTTLIQK EENVISLQASYMGKENLKKRIAEIEIVKEEFNEHLEVVDKINQICKNLQFHLNKMRTFEE PPFEKEANIIVDRWLDINEKTEDYYENLGRALALWDKLFNLKNVIDEWTEKVLQEMGLHQ LTEEEREKLREELQVHEQKSSEFSKRVAKIQSLLQSSDIPLELQVMESSILNKIEHVKMR LTGEPNYCALSGSPAELREDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQ KHSMILLENQIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNEWFSN VKMNLKDCFESSETKKSVEQKLQKLSDFLALEGRGSKIQQVASVLNHVKKHLPKAHIKEL NSWIVSQETDLEKMESICQVRAKELDYYLQRLLRLQDDHRNLSKWLTNQEEKWKEMEESG EKTELFGQALARKREQFESMAQLNNSLKEYGLTEEEEIIMESTHLTDRYQTLLRQLCEID EDNKLLPAEDQSFKDLAHDVICWITGIKESLMVLNSSEGKMTLEERIQKIKEIILLKPEG DARIQRIMSQAESSEAPLVPQTLTDIKNQWDNTLHLAKTYLSHQEKLLLEGEKYLQSKED LRLMLTELKKKQEVGFALQHGLQEKKAQLKIYKKFLQKAQDLTSLLKELKSQGNYLLECT KNPNFSEEPWLEIKQLHESLLQQLQDSVQKLEGHVQEHHSYQVCVTDLKTALDNISEEFV GFSDKPVDQEAVEEKLQKLQELEDRLSLQDGALETIVALAKSIKQNTSSAGQKIIKDDIK SLKCKQKDLENRLESAKQETENCLHSILKSKRSTEKKEKVSLAGSERQVTSAVQESTQNS AVVGELEEDGEINKNSAVKMVLSRQVSLNVQEIMKNTEDEQKVNELQNQPLELDVMLRNE QLKEIEELYTHLEAKKAAIEPLEETESLNETEAGASVLPRARHSVHRLDSLLQALATLKK NKESQYCCLKDFQERLAAIESLMRALLTEKESLKVGSLDSVTYLDKIKKFLASIEKEKGS LSKVKIEWENLSNCPTDMDKKLLESQIKQLEHSWEQVEQLVQKKYTQQVVEHDEFTFLRS RIQDLETRLQQQQQCLLLRLNSPEQEEKQSIVALATELHTIKHRFSVLKGQTELQMKRIW GEKEKKILEDAINNLQRQLEALEPLNIEVENQIKNCDVRNEMKETILWVKNLLGELIPTI SLFPDNILLQIRKCKVTHEGILDKQQAVESLVKEVKDNIPNFTAHESDDLNNLLQDLQNQ YQMLVLKSTQRSQQLEFKLEERSKFVASIEKVQLSLQGNETLIIPQMETTSTETELEHQR VTLTTSQKELREIESVLSACLEELTDIYKDLSVFEKLFLDDQLKNLKTRANRTQRFIQTK HNQVEHKLNFYREFHEKTSALQKEVDNIQHNELLLNQEVNQDVKEHSYHLKDRLAGIQSS ILRVLKLKEVFDCAGLNWDCSQLDQLQTLVFQKEKELEEKIKQLDTFVEEYGKYQASLSE LRAVDLQIKKRAEAVLKTPNTSSESSLLNAQILNQKIEKAICLSHEIIKKLSENKAFDDS FKEKEILQIKLYVEEHGTLRTVLQNIALEFQPKEMDEENFQDKLEHSLHVLNQIKSQLQQ PLLISLKTEHIQSEKDHCEAFQEQVQAEICSVRAVTVAEKQREENSFEASDTESKLRDIE DLHMQLSASLDLRTNVLNDAHENMTHYNEAVTRAMRIIAAFEAIFASHRVDLDNPQEALG RPRWKQEELESTIADIQDLTEKLEAVSSPEAKQQLQCTLQELVSKNAAVREAGKVKEAEI ERCLENYKCYRKIKEKIYANLNQMETVLGQAMSPLPVSYKEALEHLEQSKALVSNLISTK EELMKLRQVLRHLRPACTDSDGVCLFRTASALWEKWLSLLEAAKEWEMWCEELKQEWKFV SEEIEREAIILDNLQEELPEISKTKEAATTEELSELLDCLCQYEENVEKQQLLLTLLLWR IKSIQNAPESLEAVEAVPAFQEITSMQERCNKLLQKAKKNKEMVQKEIQERHSFTKEIIS LKNLFQQTTTSFQNMALQEDPEKAEEFEELQSVLTKGKLTFENIMEKLRIKYSEMYTIVP AEIESQVEECRKALEDIEEKISNEVLKSSPSYAMSSKIDEINNGLYNVEKMLQQKSKNIE KAQEIQKKMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWMDKLMVPFQQYQQVSQRAE SRTSQLNKATIKMEEYHDLLKSTEAWIERTSRLLANPADYDSSNVLSHRASTLQMALEDS EQKHNLLHSVFTDLEDLSVIFETDDFAQSVHELRRQVTALQQKIMESLPQIQQMADDVVA IETEVKPMEKRVSKIKTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTIAEIVSYQVEL RLPQAGMKPLPVFQRTHQLLQDIKLLENVTQEQNELLKIVIKQTNECDEEIENLKQILNN YSAEFSPEHISPGQAASLPQIQGEIEAVEKQILSLNQKKEDLLVDLKATVLNLHQRLQQE QRDSEKEMLSAGASEEDGVAERDVSQWKPDRTGAMSFLPAVEEEAEESSLKSENGDKEAE PSSGPWSLLGKHDKDIEEDRASSSSGTIIQEAAGRISTCASSMAQILAPDSLGPEQGPEF SLSPNQTEEGATPPIEAAALGFSDEQGAFEAKVEKPRLEPTEVLHVCKTQVAELELWLRQ ANVAFEPETLDADMQQAVEQQLVGCQAMLTEIEHKVASLLENCKDQGLGDSGATQQEAEA LSLKLKTVKCNLEKVQVMLQEKYSEDQHPTLLKKPSEHQKVLQPDNLSEFESVVTERPQF SKQKDFQQQQVLELSPMEQKDFIKFIEMNAKEMWPQYCQHDKDATHKSSVSDKASSPEND ASDSVLSPQGRSGDKWQYLHHELSSKVRLPLPQRVQPQVATNMSILPSVSVYNFRYPATE ELKTYTTQLEDLRQEANNLQTQGNMTEETFINVDKKLFELFLTLSQCLGSVEEMLQTPGL FREDACAQQVHYETLALELKKLYLALSDKKDDLLKAMTWPGKNTSLLLECFDNLQVYLEH TQAAAASRSKSLKAGLDYNRSYQNEIKRLYDQLIKNKASLQQSLNEISGQSIDEQLQKAD AYTVELQNSESRVAKLRDEGESLHLPYVLLQEVYKLEDVLDSMWGILRARYTELSSPFVT ESQQDALLQGMVELVNIGKEKLAHGHLQQTKSKVALQAQIQNHKLFFRKLVADMLLIQTY SNKMLPSLLQKKETSWAEQVKEVKLLEEKSHQYGIKLQSLLQKWEEFDENYASLEKDLEM LVSTLPSVSLVEETEERLAERISFYQQIKRNIDEKQARLYQTLNEGKQLVASVNCPELEG QMAKLEEQWLSLNKKIDHELHRLQTLLKHLLSYNRDSGQLTKWLESSQQTLQYWKEQSLS VSQDLGTIRSNINDFLEFSKELDEKSSLKTAVVSTGNQLLHLKEADTATLRASLAQFEQK WTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVERQTADEDAEHSLSSASQVKS LLRKYKEFRMEMDFKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWHRVHG TLNRKLQHLEQLLESITENENKIQILNNWLEVQEERLKTLQKPENVISVQKMLLDCQDIE NQLAIKSKALAELRQSCLTSESGTMPLLADTASRIDGLFQKRSSVINQVNELKTSMQSVL QEWKIYDKLYDEVSTMTIRFWYCMEHSKPVVLSLEALTCQVQNLQSLQDEAESSEGSWKK LQEVTGKLKDYCPSVAEIIEEKCQDTHTRWTQVNQDIADQLQKAQSLLQLWKAYNSAHTE AAARLEQQEAKYRQLANINMSGNNLAEILTPALRDLKELQHDVQKTKEDFLQNSTLLDRL PQPTESSTNVLLSGQLHLLQRASYLEKMLLVKANGFEVVLSQFKDFGDQLESLKGLIMHE EENLDKLYQQEKEENPDLFLNHVLALTAQSPEVERLNEVSLRLPLSDIAVKTLQNLNRRW IRATATGLERCSELQGTGLSEKFLSCCEKWVQLLEKIEETLKANITDSLPALLEQQKTYE MLEAEVSINQTIADSYITQSLQLLDTTEVEKKPEFVLNFTRLRDRWQSAVQSVRQRKSDI SGLVRQWQSFTTSEEDLLRFLTDTTHLLSAVKSQDCYSLYQTRSLIHELKNREIHFQRWQ PTYALTLEAGEKLLNITNLETKESIDKRISQLQDNWKDTKLQVGEMIKQFQSIAETWDQC EKKIKKLESRLQVLKAQSKDPLPELHEDLLKEKELIKELEKSLANWTQNLKELPTMKTDL TQHILVEDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNSWIVFNEKNKELCAWLVQ MENKVLQTADISIEEMIEKLQKDCMEEINLFSENKLQLKQMGDQLIKASNQTRAAEIDDK LSKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCD DQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDR RWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKPAERTAAYPNSSEVLYTNAKEE LKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNLQKRVTA VLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITL NTNKIDQLIVFGEQLIQKSEPLDAVLIEDEVEELHRYCQEVFGRVSRFHRRLTSHAPGLE DEKEASENETDMEDPREIQTDSWRKRGVSEEPSSPQSLCHLVPPAPGPERSGCETPVSVD SIPLEWDHTGDVGGSSSHEEDEEGPYYSALSDVEIPENPEAYLKMTTKTLKASSGKSISE GHSWHVPDSPSCPKHHYKQMGGDRNVQPTPSDSSTPYKPAYVKLLLSPGTDGDKEGPQAL NGSPQQEDEGLAGRPGQQSGAFDRWELIQAQELHNKLRIKQNLQQLNSDISNISICLKKT EAELETLKMAKPPKDMQEMEPRVKKLKEILKAFETYKALVVSVNVNSKEFLQTESTESKE LQGRVGQLRLQWDAAQGAVESWRDSLRQSLMQCQDFHQLSQNLLLWLASAESQRQKAHVT DPKADPQAVLECQEQLMQLEKELVERQPQVNSLQEISNSLLIKGHGEDYIEAEEKVHVIE KKLKQLLEQVSQDLMSLQGHQNPDSSLPGLDEADSGDQPPAASVPALQAKQFGAERTTKV KNKTDSRVPRGSRPQRSFLCRVLRAALPLQLLLLLLLLLACLLPSSEEDYSCTQANNFAR SFYPMLRYTNGPPPT NT seq 20748 nt NT seq  +upstreamnt  +downstreamnt atggcgtctacccctgtgcttcccgctgaagatgagcaggtttccttgggcatcgatgat ctccatatttcactgcaagctaaacaggaagacactcagaagaaaaccttcacctgctgg ataaactcacagttggcaaagcacacccccccctcggttatatcagacctcttcacagac attagaaaggggcatgtcctcctggacctgctggaagtcctctcaggacaacaattgcct cgagataaaggatccaatccattccagtgtaggatcaacatagagcatgccctgacgttc ctgcaaagccgatccatcaagctaataaacattcatattactgacattatagatggaaaa ccatccattattcttggcctaatttggacaattatactgcactttcatattgaggagctt gcccagactctgccttgcaattatgatcaaccttcccccgacagcatgagtgtggttgac tcatctcctacctcaagtcctccagctaagaaatgctccaaagcccaagaaagatggcag atgtctgcaaagaacgctcttctcttgtgggctcaggagcaatgtgccacgtatgagtct gtcagtgtgacagattttaagtcaagctggagaaatgggatggcttttttggccatcatt cacgccttgcgaccaaacctgattgacatgaagagtgtgaagcatagatccaacaaagac aatctgaaggaggcctttagaatcgcagaacaagaactgaagatccccaaactgctggaa ccagaagatgtggatgttgtgaatcctgatgaaaagtcaatcatgacctatgtggcacag tttctgcagtattcaaagaaggcacctgggactggagataaagctcagggaaagatgaaa gatgctatggtctggttaactctgcaagagaaaaaactacagaaaacgctaaaggattca gaaaaggagaccttctttaaaaagtatgaaagcttgctgtcctttctggagtcattcaat gaagaaaaaaaaccctttttggacatcctgtccgtcaaaaggaatccggatgagctgaat gaagatcagttacagatgaaagaagcctgggatggcctcaaccaccagattaatgtgtgg aaaatgaagctgaatgatgacctgccgttgcccctccatcaaatcgaagcttggctccat gaggtggaggagcttatagatgaagatttgccagccttccaggattattctgaagccatg gctctaatacaagagaaaattactttattcaagagtctgatggataaatctgactgtcat tcgaatactctcctggcatttgaaaatagagatgaaaaacatttaccattggtaccgcct aacaaactggaggaaatgaaaagacgaatcaacaacatttccgggaaaaaatttattcca cttctagaatttcattactataagtgctcagttcttggtttgctagatgaagtgaaatca aaactggatgtttggaacagcaaatacgggagcaaagaatctgtggaatttcttctggaa gactggcgcaaatttattgaagaaaaagagttcctagctcaacttgaaacttcttttcag aaatgtggagaaattcataagaatttggctggagaatatcagaatattagtgaagaatat gcgatggtggaatctaatgtctgtatgtctagaaaaaatatatacgatgtgaagtctact ctacaagaagtcctggcgtcctgggctgcttatgcggagaagcttcgctccctaaaggct tgttttgtggagacaaagaaggaacaagttacagaggttccctttgagacactatcccaa tggaatctggaacatactactttaaatgaagtgggaaatttcttaattcaagtcagctat gatgaagttggatcatctatttctaaagaactaaggaggctgaataaaagatggagaaag tttattacaaaaactcagcttgaaatgaacctgccacttataaaaaaacaagatcagccc attcttgacaattctggaaatattcagctacctaaagaagaaaaaccaacagttgatttt tcagcagatatatcaatagaacttccggaaaatcataatcagaatatgaaggctgaggaa gaatctgaaaaagagaatgaaggattcacggaacaactgaaagtggctgaagaggttgaa aaactcatcggacaagtggaggtctgggaggcagagaccaaatctgttttggatcttctg agacaccaagatgatgtggacacctcaatggaagaatctttgcagcatcttattgccaaa ggctctatgtacgaagagcttgtgtctagaactgaagatacattacaaatggatgtgcaa aatgtttcaagccaggaatctctccaacatgttctcacggctgggcttcaggcaaagatt caagaagctaaggagaaagtccagattaatgtggtaaaattagttgcagtgttgaagaac tcaactgatgtttcaccagagctggatgtcaggctgaagatggaagaattacagaaggaa cttgaatcatacattacgagggctgagcagttacttgcccaaagagagagccggagtgga ctaatttcaaaatacaaggaagcgctaataatttttaacactaaaagcctggccaagtat ttgaaagctgttgaagaactgaaaactaatgtaaccgaggatgtaaagctgtctttggaa gaaaagagtggagatgtctgtgccaagtgggagtctcttcatcatgaaatggctttgtat attcaacaactaaaaatagacattgaaaaaggaaaacttagtgacaatatttcgaaactt gaaaaacaaataactaaagaaaagaaactaattcgcagaggaaggacaaagggtctcatc aaggagcatgaggcctgcttttctgaggaaggcagtctgtaccagcttgatcaccacatg aatgtcctgcgggagctgtgtgaagagctgacttcgcagaagagtcaacaagaaatgagg agagtgcttaaagattatgaacaaaagatagaaagacttcggaaatgcgcttctgagatt catatgacactgcaacctacggtgggaggcacatcgaagaacaaggggaccacgaacaca tctgagaatggaggaaggaatgcccacagtgaggtgccatctgcagaatcagatgatcag ccatcaactgaaaaggcaatggactcggttaagaactttaccccggaatctgagttgaat cctccacaggaagaaagcattatggagaagcatggaaaggatcacagtgcgtccacaaat agtttactacagaggtatgaaactcacagagaaactcttgaactacacctgcaaaacagc aaattcaggattacttctgatttctcgagtgacagggacaggagtagcacttgtctgcag gaaaaactgacagatctacaggtcttaaaaaatgaaactgatgcttgctggaaagagttt gaaatcacttcactgaagttagaagaacttgagagtgacgtacagaagccttttataatt aagacaagagacagtttaaaggaaaaagaaagagagcttcagatgagtcttaataccaga atggagtctttggagactgcactgcagattgtggtacctgtggagaaggaatcgctcctt ctctgtggctcagacctgctcctccgtgaaatggccattcaagaatttcatctcagtgat gctgatggcatttatcaacacctggggactatccaagattccatagcaaaacagattgaa atatgtaacaatttggaacagtcgtgcaactctgcattaaaggaattacaccctcttgat ctacatgtaacacagaatattatattggaacacagaacacaacttgaagaaatgaaccac aaggtgcagaggagtcaagatgccctcaaagtgctggaagactttttggcttctctgaga acagctgaactctctcctgagcttgttacagacctttcagcctcagagacacaggtggaa ccagaaagtactttgacagtaggaaagaaagagggagaaatccaggtgatgaaagacaag gccagacatttggatgaatgtttgaagatgcttaatataagctttaaagatgctgaacag ggtgaagacagctcttgtgaaaaacttcttgatgctttgtccaaaaacgtatttgaaaaa ggtggctatggcacacaggaggaactcactgaagaagacaagttactagagacttgtatt ttcaaaaataatgaactccggaaaaatatccaagacgtgcacgatcaaatcagtaaaatt ggtctgaaggatccaaccgttccagctgtgaaacaaaggaaaaaatcattaatcagactg gataaggatctggatgaatatgaagaagaaaagaaacacctgcaacaagtggcaaattct cttccacagttcaaagatggcagggaaaaagctctgagtcaacagtgccaagagacagcc ctcttgtgggagaatgcaaaagcttcggtcactgaatgccttgaccaatgtgagagagtt ttggagctcttaaaacaatatcagagttttaaaagtgtcctgacaactttgattcaaaaa gaagagaatgtcatctcccttcaggcttcatacatgggaaaggagaatctgaagaaaagg atagcagagattgaaattgtcaaagaagaatttaatgaacatttagaagttgtagacaag attaaccagatctgcaaaaatctacaattccatctaaataaaatgagaacctttgaagag cctccttttgagaaagaggctaatattattgtggatagatggcttgatataaatgagaag acagaagactactatgaaaatcttggtcgagctcttgctttatgggacaaactttttaac ttaaaaaatgtcattgatgagtggactgaaaaggtccttcaagaaatgggattacatcaa ctgactgaagaagaaagagaaaagctgagggaagagttgcaagtccatgaacaaaaatct tcagaattttctaaaagagtggctaaaatacagtctttgcttcaaagtagtgacatacct cttgaattgcaggtcatggagtcctctattttgaacaaaatagagcatgtaaaaatgcgt ttaacaggagaacccaactactgtgccctcagtggcagcccagctgagctaagggaggat ctggaccaagccaagacccagattggaatgacagagtccctcttaaaggccctgtctcct tccgacagcttggagatctttaccaaactagaggagatacaacagcagattttacagcaa aagcacagtatgatattacttgagaatcaaataggttgtctgactcctgaactctctgaa ttaaaaaagcaatatgaaagcgtcagtgatttatttaataccaaaaaaagtgttttgcaa gatcacttttcgaagttactgaatgatcagtgcaagaactttaatgagtggttcagcaac gttaaaatgaaccttaaggactgttttgaatcatcagaaacaaaaaagagtgtggaacaa aagctacaaaaactttctgatttcttggctcttgaaggaagaggcagtaaaatacagcag gtggcatctgtgttaaatcatgtgaagaagcatctgcccaaagcacatattaaggagctt aacagttggattgtaagtcaagaaactgatttagaaaaaatggagtccatatgccaggtg cgagcaaaggagcttgattattatttgcagcggctactgagactccaggatgaccataga aacttgagtaagtggttgactaatcaagaagagaaatggaaagaaatggaagaatcagga gagaaaactgagctatttggccaagctctagccagaaagagggaacagtttgaatctatg gcccagttgaacaactctttgaaggaatatgggcttactgaagaagaagaaataataatg gaatccacacatttgactgatagataccagacattattgagacagttgtgtgaaattgat gaagacaataagttacttcctgctgaggaccagagctttaaagatcttgcacatgatgta atttgttggataacagggattaaggagtcccttatggttctgaattcatctgaaggcaaa atgacacttgaggagagaatccaaaaaataaaggaaatcattttactgaagcctgaaggg gacgctagaatacagagaatcatgagtcaggccgagagcagcgaagctcccttggttcca cagacccttactgatatcaagaaccagtgggacaacacgctccatttagccaaaacgtat ctaagccatcaagaaaagcttctactagaaggagagaagtatttgcaaagtaaggaggat ctgagattaatgctcacagaactgaaaaagaaacaagaagtgggctttgctctgcaacat ggattgcaggagaagaaagctcagttaaaaatttataagaaatttctccagaaagcacaa gatttgacatccttgctaaaggagttaaaatctcaaggaaattacctcctagagtgcact aaaaatcccaacttcagtgaagagccttggctggaaataaagcagctacatgaaagtctt cttcaacaactacaggactctgtgcagaaattggaaggtcatgttcaagaacaccactca taccaggtttgcgttacagacctgaagacagcattggacaatatctctgaggaatttgtt ggtttttctgataagcctgtggatcaagaagcagttgaggaaaaactgcagaaactgcag gaactagaggatagactcagtttacaagatggcgcgttagaaaccattgtagctttagca aaatccatcaagcaaaatacatcttcagcgggacagaagattattaaagatgatataaaa tctcttaagtgtaaacaaaaagatttggaaaacagacttgaatctgctaagcaggagaca gaaaattgtctccacagcattctcaaatcaaaacgctcaacagaaaagaaagaaaaggtg tctctggcaggcagcgagaggcaggtcacgtctgccgtgcaggagtccactcagaactca gctgtggtgggagagttggaggaagacggggaaataaacaagaattcagccgtgaaaatg gttttgtcaagacaagtttctctcaatgttcaagaaatcatgaaaaacactgaagatgag cagaaagtcaatgagctgcaaaatcaacctttagaattagatgttatgttaagaaatgaa caattaaaagagatagaggaactgtatacccacttggaagcaaagaaagcagccattgaa 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gatttcatcaaattcatagaaatgaatgctaaggaaatgtggccccagtattgccaacat gataaagacgcaactcacaaatcatctgtgagcgataaggcatctagccctgaaaatgat gcttcagactcggtcttgtcaccccagggccgcagtggagataagtggcaatatttacat catgaactctcatcaaaagtaagactacctctgccgcaacgtgtgcagcctcaggttgcc acaaatatgagtattctacccagtgtgagcgtgtataactttagatacccagcaactgaa gaactgaaaacttatactacccaacttgaagacctgcgtcaagaagcaaataatctgcag acacagggaaacatgactgaagaaacattcataaatgtggataaaaaattatttgaacta tttctgaccctcagtcagtgccttggcagtgtggaggagatgctgcagacacctgggctc ttcagagaggatgcttgtgctcagcaggtgcactatgagacgctggctcttgagttgaaa aaactttacttagctttgagtgacaagaaggatgatcttttaaaagccatgacttggcct ggcaagaacaccagcttgctccttgaatgttttgataacctccaggtctacctggagcac acccaggctgcagctgcctctagaagcaagtccctgaaagccggcctcgactataaccgc agttatcagaatgaaataaagcgattatatgatcaacttattaagaataaagcatcttta caacagtctttgaatgagatcagtggccagagtattgatgagcagcttcagaaagcagat gcgtatacagtggagctgcagaactccgagagccgagttgcaaaactaagagacgaaggg gagagccttcatttaccttatgttttacttcaagaggtttacaaattagaggatgtactt 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gtgtctgtcaatgtgaacagcaaggaatttctgcaaaccgagagcaccgaatccaaagag ctccaggggagagtcggccagctgaggctgcagtgggacgcggcacagggcgcggtggag agctggagagacagcttacggcagtcgctcatgcagtgccaggacttccaccagttgagt caaaatctgctactgtggttagcgagtgccgaaagccagaggcagaaggctcatgtcact gatccaaaggcagacccccaggctgtcctggagtgtcaggaacaactgatgcaactagaa aaggagctagtggaacgtcaacctcaagtaaactccttacaagagatctcgaacagcctt cttattaaggggcatggagaagactatattgaggctgaagagaaggtgcatgttattgag aagaaactcaaacagttactcgagcaagtgtcccaagacttaatgtccttgcagggacac cagaacccagactcgtctctgcctggcttggacgaggcagactctggagaccagcctcca gcagcgtccgtgccagctctccaagcaaagcagttcggagcagagagaactacaaaagtc aagaacaagacagacagcagggtgccccgtggctcgcggcctcagcgctccttcctctgc cgcgtgctcagggcggcgctgcccctgcagctgctgctcctgcttctcctgctcctggcc tgcctgctgccctcctccgaggaggactacagctgcacacaggccaacaactttgcgagg tccttctaccccatgctgaggtacaccaacgggccaccccccacctag

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