Escherichia coli O6 K2 H1 CFT073 (UPEC): c0003 Help Entry c0003             CDS       T00106                                  Symbol thrA Name (GenBank) Aspartokinase I   KO K12524   bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] Organism ecc  Escherichia coli O6:K2:H1 CFT073 (UPEC) Pathway ecc00260   Glycine, serine and threonine metabolism ecc00261   Monobactam biosynthesis ecc00270   Cysteine and methionine metabolism ecc00300   Lysine biosynthesis ecc01100   Metabolic pathways ecc01110   Biosynthesis of secondary metabolites ecc01120   Microbial metabolism in diverse environments ecc01230   Biosynthesis of amino acids Module ecc_M00016   Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine ecc_M00017   Methionine biosynthesis, aspartate => homoserine => methionine ecc_M00018   Threonine biosynthesis, aspartate => homoserine => threonine Brite KEGG Orthology (KO) [BR:ecc00001]  09100 Metabolism   09105 Amino acid metabolism    00260 Glycine, serine and threonine metabolism     c0003 (thrA)    00270 Cysteine and methionine metabolism     c0003 (thrA)    00300 Lysine biosynthesis     c0003 (thrA)   09110 Biosynthesis of other secondary metabolites    00261 Monobactam biosynthesis     c0003 (thrA) Enzymes [BR:ecc01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.3  homoserine dehydrogenase      c0003 (thrA)  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.2  Phosphotransferases with a carboxy group as acceptor     2.7.2.4  aspartate kinase      c0003 (thrA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Homoserine_dh AA_kinase ACT_9 NAD_binding_3 ACT_7 ACT DUF6247 Motif Other DBs NCBI-ProteinID:  AAN78503 UniProt:  A0A0H2V3Y0 LinkDB All DBs Position 985..3510 Genome browser AA seq 841 aa AA seqDB search MKNLRLCRRIFISTKGNEVTTMRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSA PAKITNHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFA QIKHVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGH YLESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLR ADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIP CLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAM SRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAII SVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQML FNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLE NWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNK KANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGS LSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARKLLILARETGRELELADI EIEPVLPAEFNAEGDVAAFMANLSQLDNLFAARVAKARDEGKVLRYVGNIDEDGVCRVKI AEVDSNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLG V NT seq 2526 nt NT seq  +upstreamnt  +downstreamnt ttgaaaaacctccggctatgccggaggatatttatttcgaccaaaggtaacgaggtaaca accatgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgg gttgccgatattctggaaagcaatgccaggcaggggcaggtggccaccgtcctctctgcc cccgccaaaatcaccaaccatctggtagcgatgattgaaaaaaccattagcggccaggat gctttacccaatatcagcgatgccgaacgtatttttgccgaacttctgacgggactcgcc gccgcccagccgggatttccgctggcacaattgaaaactttcgtcgaccaggaatttgcc caaataaaacatgtcctgcatggcatcagtttgttggggcagtgcccggatagcatcaac gctgcgctgatttgccgtggcgagaaaatgtcgatcgccattatggccggcgtgttagaa gcgcgtggtcacaacgttaccgttatcgatccggtcgaaaaactgctggcagtgggtcat tacctcgaatctaccgttgatattgctgaatccacccgccgtattgcggcaagccgcatt ccggctgaccacatggtgctgatggctggtttcactgccggtaatgaaaaaggcgagctg gtggttctgggacgcaacggttccgactactccgctgcggtgctggcggcctgtttacgc gccgattgttgcgagatctggacggatgttgacggtgtttatacctgcgatccgcgtcag gtgcccgatgcgaggttgttgaagtcgatgtcctatcaggaagcgatggagctttcttac ttcggcgctaaagttcttcacccccgcaccatcacccccatcgcccagtttcagatccct tgcctgattaaaaataccggaaatcctcaagcaccaggtacgctcattggtgccagccgt gatgaagacgaattaccggtcaagggcatttccaatctgaataacatggcaatgttcagc gtttccggcccggggatgaaagggatggttggcatggcggcgcgcgtctttgcagcgatg tcacgcgcccgtatttccgtggtgctgattacgcaatcatcttccgaatacagtatcagt ttctgcgttccgcaaagcgactgtgtgcgagctgaacgggcaatgcaggaagagttctac ctggaactgaaagaaggtttactggagccgttggcggtgacggaacggctggccattatc tcggtggtaggtgatggtatgcgcaccttacgtgggatctcggcgaaattctttgccgcg ctggcccgcgccaatatcaacattgtcgccattgctcagggatcttctgaacgctcaatc tctgtcgtggtcaataacgatgatgcgaccactggcgtgcgcgttactcatcagatgctg ttcaataccgatcaggttatcgaagtgtttgtgattggcgtcggtggcgttggcggtgcg ctgctggagcaactgaagcgtcagcaaagctggttgaagaataaacatatcgacttacgt gtctgcggtgttgctaactcgaaggcactcctcaccaatgtacatggccttaatctggaa aactggcaggaagaactggcgcaagccaaagagccgtttaatctcgggcgcttaattcgc ctcgtgaaagaatatcatctgctgaacccggtcattgttgactgtacttccagccaggca gtggcggatcaatatgccgacttcctgcgcgaaggtttccacgttgttacgccgaacaaa aaggccaacacctcgtcgatggattactaccatcagttgcgttatgcggcggaaaaatcg cggcgtaaattcctctatgacaccaacgttggggctggattaccggttatcgagaacctg caaaatctgctcaatgctggtgatgaattgatgaagttctccggcattctttcaggttcg ctttcttatatcttcggcaagttagacgaaggcatgagtttctccgaggcgaccacactg gcgcgggaaatgggttataccgaaccggacccgcgagatgatctttctggtatggatgtg gcgcgtaagctattgattctcgctcgtgaaacgggacgtgaactggagctggcggatatt gaaattgaacctgtgctgcccgcagagtttaacgccgagggtgatgtcgccgcttttatg gcgaatctgtcacagctcgacaatctctttgccgcgcgtgtggcgaaggcccgtgatgaa ggaaaagttttgcgctatgttggcaatattgatgaagatggcgtctgccgcgtgaagatt gccgaagtggatagtaatgatccgctgttcaaagtgaaaaatggcgaaaacgccctggcc ttctatagccactattatcagccgctgccgttggtactgcgcggatatggtgcgggcaat gacgttacagctgccggtgtctttgctgatctgctacgtaccctctcatggaagttagga gtctga

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