Escherichia coli O6 K2 H1 CFT073 (UPEC): c0726
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Entry
c0726 CDS
T00106
Symbol
mrdA
Name
(GenBank) Penicillin-binding protein 2
KO
K05515
penicillin-binding protein 2 [EC:
3.4.16.4
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00550
Peptidoglycan biosynthesis
ecc01100
Metabolic pathways
ecc01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
c0726 (mrdA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
c0726 (mrdA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ecc01011
]
c0726 (mrdA)
Enzymes [BR:
ecc01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
c0726 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:
ecc01011
]
Peptidoglycan biosynthesis and degradation
DD-Transpeptidase (Class B PBP)
c0726 (mrdA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Transpeptidase
PBP_dimer
PBP_dimer_2
Motif
Other DBs
NCBI-ProteinID:
AAN79199
UniProt:
P0AD66
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All DBs
Position
complement(706307..708208)
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AA seq
633 aa
AA seq
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MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQIVRFTDYQTRSNENRIK
LVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLTDDDIAAFR
KERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVS
KINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLK
EVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNLFVDG
ISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTTLFDPGWWQL
PGSEKRYRDWKKWGHGRLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGID
LAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGIVKV
PHLLMSTAEDGKQVPWVQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFASAPYK
IAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAV
GTLMRQILDHIMLGDNNTDLPAENPAVAAAEDH
NT seq
1902 nt
NT seq
+upstream
nt +downstream
nt
atgaaactacagaactcttttcgcgactatacggcagagtccgcgctgtttgtgcgccgg
gcgctggtcgcctttttggggattttgctgctgaccggcgtgcttatcgccaacctgtat
aatctgcaaattgttcgctttaccgactaccagacccgctctaatgaaaaccgcattaag
ctggtgcctatcgcacccagccgcggcattatctacgaccgtaacggtatccctctggct
ctcaaccgcactatctaccagatagaaatgatgccggagaaagtcgataacgtgcagcaa
acgctggacgctttgcgcagcgtggttgatctgaccgatgatgatattgctgcattccga
aaagagcgcgcacgttcacaccgtttcacctctattccggtgaaaactaacctgaccgaa
gtacaagtagctcgctttgccgtcaaccagtaccgttttcctggcgtcgaagttaaaggc
tataaacgtcgttactatccttacggttcagcgttgacccacgtcatcggctatgtgtcg
aaaatcaacgataaagacgtcgaacgcctgaataatgacggcaaactggccaactatgcg
gcaacgcatgatatcggtaagctgggcattgaacgttactatgaagacgtgctgcacggt
cagaccggttatgaagaggttgaagttaacaaccgtgggcgtgttatccgccagttaaaa
gaagtaccaccgcaagccggacacgatatttacctgacgctggatctcaaactccagcaa
tatattgaaacgctgctggcgggtagccgcgcagctgtggtagtcaccgatccgcgtaca
ggtggggtgttggcgctggtttccacgcctagttatgacccaaacctgtttgttgacggt
atctccagcaaagattattccgccttgctgaacgacccgaatacaccgttggtgaaccgc
gccacacagggggtttatcctcccgcgtctacagttaaaccctatgttgcggtttcggca
ttgagtgccggggtgatcacgcgcaatacgacgctgtttgaccccggctggtggcaactt
ccaggttcggaaaaacgttatcgtgactggaaaaaatggggccacgggcgtctgaatgtc
acaagatcgctggaagaatctgcggataccttcttctatcaggtggcctacgatatgggg
atcgatcgcctctccgaatggatggggaaattcggttatggtcattacaccggtatcgac
ctggcggaagaacgttccggtaacatgccaacccgcgaatggaaacaaaaacgctttaaa
aaaccgtggtatcagggtgacaccattccggttggtatcggtcagggttactggacggcg
acccctatccagatgagtaaggcactgatgatcctgattaatgacggtatcgtgaaggtt
ccgcatttgctgatgagcaccgccgaagacggcaaacaggtgccatgggtacaaccgcat
gaaccgcccgtcggcgatattcattccggttactgggagctggcgaaagacggtatgtac
ggtgttgctaaccgccctaacggtacggcgcataaatattttgccagcgcaccgtacaaa
attgcggcgaaatccggtaccgctcaggtcttcggtctgaaagcgaacgaaacctataat
gcgcacaaaattgccgagcgtttacgtgaccacaaactgatgaccgcctttgcgccatac
aacaatccgcaagtggctgtcgccatgattctggagaacggtggcgcgggtccggcggtt
ggtacgctgatgcgccagatcctcgaccacattatgctgggtgataacaacaccgatctg
cctgcggaaaatccagcggttgccgcagcggaggaccattaa
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