Escherichia coli O6 K2 H1 CFT073 (UPEC): c3080
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Entry
c3080 CDS
T00106
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00230
Purine metabolism
ecc01100
Metabolic pathways
ecc01110
Biosynthesis of secondary metabolites
Module
ecc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
c3080 (purL)
Enzymes [BR:
ecc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
c3080 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AAN81529
UniProt:
Q8FF26
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All DBs
Position
complement(2954523..2958410)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggttaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagttgtttgcacaccatcaaccgactccggtcaccagc
gtagatttgctggggcagggccgtcaggcgctaattgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgcgttcacaaagctgggtcgtaac
ccgaacgacatcgagctgtatatgtttgctcaggcgaactctgagcactgccgccacaaa
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaacaccttcgaaaccacgccagaccacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagttgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccggacgtggcgcaaagccgaaagctggtctggttggtttctccgtatccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaaacctgagcgcattgtt
accgcgctggacatcatgaccgaaggcccgctgggcggtgcggcgtttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcatctggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcgccatacgcggtgattggtgaagcg
accgaagaactgcatctttctttgcacgatcgtcattttgataatcagccgattgatcta
ccgctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgcgtg
ctgcatctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcagtcactaccgccagcctcgacagctactatggcgaagcgatggcaattggcgaacgt
gcgccagttgcgctgctggatttcgccgcttctgcccgtctggcagtcggtgaagcgcta
accaacatcgccgcaacacaaattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgataccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgttgtcgctg
gtgatttccgcatttgcccgcgtggaagatgtacgtcacaccattacgccgcagctttct
accgaagataacgcactgttgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcactggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtt
gcccaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgtggcattgacgcggatatcgccactctgggtgacgatcgcctggctgcattg
tttagcgaagaactgggtgcggtgattcaggttcgagccgctgaccgtgaagccgttgaa
gcggtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtatttagcgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgtctgcgtgacaacccggag
tgtgccgatcaggaacaccaggcgaaatcaaacgacgccgatccgggcctgaatgtgaaa
ctgtcgtttgatatcaacgaagatgtggcagcaccgtttattgccactggcgcgcgcccg
aaagttgccgtactgcgtgagcagggtgtgaactcccatgttgaaatggcggcagctttc
caccgtgcgggcttcgatgctatcgacgtgcatatgagcgatctgctggctggacgcacg
ggcctggagggtttccacgtcctggtagcgtgcggtggtttttcctacggtgatgtgctg
ggcgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagtctggtagaagtaacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcagatgccgattgctgtctctcacggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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