Escherichia coli O6 K2 H1 CFT073 (UPEC): c4693
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Entry
c4693 CDS
T00106
Symbol
ilvD
Name
(GenBank) Dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00290
Valine, leucine and isoleucine biosynthesis
ecc00770
Pantothenate and CoA biosynthesis
ecc01100
Metabolic pathways
ecc01110
Biosynthesis of secondary metabolites
ecc01210
2-Oxocarboxylic acid metabolism
ecc01230
Biosynthesis of amino acids
Module
ecc_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
ecc_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
c4693 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
c4693 (ilvD)
Enzymes [BR:
ecc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
c4693 (ilvD)
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Gene cluster
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Motif
Pfam:
ILVD_EDD
Motif
Other DBs
NCBI-ProteinID:
AAN83125
UniProt:
Q8FBR5
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Position
4454518..4456368
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SAQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDIVVTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRSNGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKKRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctacgcgatctcggtaaactggtt
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggatcgctatgggccacgggggcatgctttattcactgccatctcgcgaactgatc
gctgattccgttgaatatatggtcaacgcccactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatt
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtttctgactcccag
agcgctcaggttgaacgatccgcctgcccaacctgcggttcctgctccgggatgtttact
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaacccacgctgatcgcaagcaactgttcctcaatgctggtaaacgcattgtt
gaattgaccaaacgttactacgaacaggatgatgaaagcgcactgccgcgtaacatcgcc
agtaaggcggcgtttgaaaacgccatgacgctggatatcgcgatgggcggctctaccaac
accgttcttcacctactggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgataagctctcccgcaaagtaccgcagctgtgtaaagttgcgccgagcacccaaaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgagctggat
cgcgcggggttactgaaccgtgatgtgaaaaacgtacttggcctgacgttgccgcaaaca
ctggaacaatacgacatcgtcgtgacccaggatgatgcggtaaaaaatatgttccgcgct
ggccctgcgggcattcgtactacacaggcattctcgcaggattgccgctgggatacgctg
gacgacgatcgctccaatggctgtatccgctcgctggaacacgcctacagcaaagacggc
ggtctggcggtgctctacggtaatttcgcagaaaacggctgcatcgtgaaaaccgcaggc
gtcgatgacagcatcctaaaattcaccggcccggcgaaagtgtacgaaagccaggacgac
gcggtagaagcgatcctcggtggcaaagttgtcgcgggcgatgtggtggtgatccgctat
gaaggcccgaaaggcggccctggcatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatggggctcggcaaagcctgtgcgctgatcaccgatggacgcttctccggcggcacc
tctggtctttccatcggccacgtctcgccggaagcggcaagcggcggcagcattggcctg
attgaagatggtgacctgatcgctatcgatattccgaaccgaggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagcccgtggcgacaaagcctgg
acgccgaaaaaacgtgaacgtcaggtttcctttgccctgcgtgcctacgccagcctggca
accagcgccgacaaaggcgcggtgcgcgataaatcgaaactggggggttaa
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