Escherichia coli O6 K2 H1 CFT073 (UPEC): c4951
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Entry
c4951 CDS
T00106
Symbol
thiC
Name
(GenBank) Thiamine biosynthesis protein thiC
KO
K03147
phosphomethylpyrimidine synthase [EC:
4.1.99.17
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00730
Thiamine metabolism
ecc01100
Metabolic pathways
ecc01240
Biosynthesis of cofactors
Module
ecc_M00127
Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
c4951 (thiC)
Enzymes [BR:
ecc01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.17 phosphomethylpyrimidine synthase
c4951 (thiC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiC_Rad_SAM
ThiC-associated
Motif
Other DBs
NCBI-ProteinID:
AAN83379
UniProt:
Q8FB77
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All DBs
Position
complement(4725411..4727318)
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AA seq
635 aa
AA seq
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MERAMSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITATQPGVRVPMREIQLSPTLI
GGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSD
YTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERI
RSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKV
NANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPI
YQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGG
SIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTL
GELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHF
TSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIR
DNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQE
VRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
ttggaacgagctatgtctgcaacaaaactgacccgccgcgaacaacgcgcccaggcccaa
cattttatcgataccctggaaggctccgcctttcccaactcaaaacgcatttacatcact
gccacacaacccggcgtgcgcgtgccgatgcgtgagatccagcttagcccgacgctaatc
ggcggtagcaaagaacaaccgcagtacgaagaaaacgaagcgattccggtctacgacacc
tccggtccgtatggcgatccgcagatcgccattaacgtgcagcaagggctggcaaaacta
cgccagccgtggatcgatgcgcgcggcgataccgaagaacttaccgtgcgcagttccgat
tacacaaaagcgcggctggcagatgatggcctcgacgagctgcgttttagcggcgtatta
acgccaaaacgcgccaaagcaggacgccgcgtcacccaactgcactacgcccgccagggt
atcatcacacccgaaatggaattcatcgccattcgcgagaatatgggtcgcgagcgcata
cggagcgaagttttacgccaccagcatccgggaatgagctttggcgcacgtctgccggaa
aatatcactgcggaatttgtccgtgatgaagttgctgccggacgtgcgattatcccggcc
aacattaatcatccggaatcggagccgatgattattggccgtaacttcctggtaaaagtt
aacgccaatatcggcaactcagcggtcacttcttccatcgaagaagaagtggaaaaactg
gtatggtccacacgctggggagcggataccgtgatggatctttccactggtcgctatatt
cacgaaacccgcgagtggattttgcgtaacagcccggtgccgatcggtacagtgccgatc
taccaggcactggagaaggtgaacgggatcgctgaagatcttacctgggaagtcttccgc
gacaccctgctggaacaagccgagcaaggtgtggattacttcacgatccatgcgggggtg
ctgctgcgctacgtgccgatgaccgcgaaacgcctgaccggtatcgtctctcgcggcggt
tcgattatggcgaaatggtgcctctcccatcatcaggaaaatttcctctatcaacacttc
cgcgaaatttgtgaaatctgtgctgcttatgacgtttcgctatcgctgggcgacggcctg
cgccccggttctattcaggacgccaacgatgaagcacagtttgccgagctgcatacgctg
ggtgaactgactaaaatcgcctgggaatatgacgtacaggtgatgattgaaggcccaggc
cacgtgccgatgcagatgattcgccgcaatatgaccgaggagttagagcactgccacgaa
gcgccattttacactctggggccgctaactaccgatatcgcgccgggctatgaccacttc
acgtcagggattggcgcggcgatgattggctggtttggttgtgcaatgctctgctacgta
acgccgaaagagcatctgggcctgccaaataaagaagatgttaaacaggggcttatcacc
tataagattgccgctcacgccgccgacctggcgaaagggcatccgggcgcgcaaattcgc
gataacgccatgtcgaaagcccgcttcgaatttcgctgggaagaccagtttaatctggcc
ctcgacccgtttactgcccgcgcttatcacgatgaaaccctgccgcaagagtccggtaaa
gtcgcccatttttgctccatgtgtggaccgaaattctgctcgatgaaaatcagccaggaa
gtgcgtgattacgccgccgcgcaaaccattgaagtgggaatggcggatatgtcggagaac
ttccgcgccagaggcggagaaatctacctgcgtaaggaggaagcgtga
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