KEGG   Escherichia coli K-12 DH10B: ECDH10B_2842
Entry
ECDH10B_2842      CDS       T00666                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase 2, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ecd  Escherichia coli K-12 DH10B
Pathway
ecd00230  Purine metabolism
ecd00240  Pyrimidine metabolism
ecd01100  Metabolic pathways
ecd01232  Nucleotide metabolism
Module
ecd_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
ecd_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ecd00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    ECDH10B_2842 (nrdE)
   00240 Pyrimidine metabolism
    ECDH10B_2842 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ecd03400]
    ECDH10B_2842 (nrdE)
Enzymes [BR:ecd01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     ECDH10B_2842 (nrdE)
DNA repair and recombination proteins [BR:ecd03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    ECDH10B_2842 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: ACB03803
LinkDB
Position
2891135..2893279
AA seq 714 aa
MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQ
QRLNWLVNEGYYDESVLNRYSRDFVITLFTHAHTSGFRFQTFLGAWKFYTSYTLKTFDGK
RYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFL
LRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLA
KENAQMALFSPYDVERVYGKPFADVAISQHYDELVADERIRKKYLNARDFFQRLAEIQFE
SGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEYDENLDYTRTGHDISCNLGSL
NIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYAITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQG
NWQPKTAKVGELFTRSGITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATS
SIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQG
LSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
NT seq 2145 nt   +upstreamnt  +downstreamnt
ttggcaacgacaaccgcagaatgcctgacgcaggaaacgatggattaccacgcgctgaat
gcgatgcttaacctctacgatagcgcaggtcgcattcagttcgataaagaccgccaggcc
gttgacgcctttattgcgacgcatgtgcgtccgaacagtgtgaccttcagtagccagcag
cagcgcctgaactggctggtcaacgaaggttactatgatgaaagcgttcttaatcgctac
tctcgcgactttgtcattacgctgtttacccacgcacacaccagcggttttcgtttccag
acattcctcggggcatggaagttttacaccagctatacgttgaagacattcgacggtaaa
cgttatctggaagattttgccgatcgagtaacgatggtggcgctgacgctggcacaaggc
gatgagacgctggcgttgcaactgaccgatgaaatgctgtcaggacgctttcagccagcc
acgccaacattcctcaactgcggtaagcagcagcgcggcgaactggtttcctgttttttg
ctgcgtattgaagacaatatggagtcgattggtcgggcggtaaattccgcactgcagctg
tcgaaacgcggcggcggcgtagcatttttgctgtcgaatctgcgagaagcgggcgcgcca
attaaacgtattgaaaatcaatcttctggcgtaattccggtgatgaaaatgctggaagac
gcattttcctatgccaaccaactcggcgctcgtcagggggctggtgcagtctatttacat
gctcatcatcccgatattctgcgttttctcgacacgaaacgggaaaatgccgacgaaaaa
atccgcattaaaacactgtcgcttggcgtggtgatcccggatatcactttccatctggca
aaagagaatgcgcagatggcgctgttttcgccttatgacgtagagcgagtttatggcaag
ccgtttgccgatgtggccatcagccaacactatgacgaactggttgccgatgaacgcatt
cgcaaaaaatacctcaacgcccgtgatttcttccagcgactggcagaaatccagtttgag
tccggctatccctacatcatgtatgaagacacggtaaaccgtgctaaccctatcgccggg
cgcataaatatgagtaatctctgctcagaaattttgcaggttaacagcgcctcagagtat
gacgagaatctcgactatacccgcacaggccatgatatttcctgcaatttaggttcgttg
aatattgcgcacaccatggattcccccgattttgcccgcacggtagagactgccgtgcgc
ggtttaacggcagtatcagatatgagtcatatccgcagcgtgccgtccatcgaagccgga
aatgccgcctcgcacgccatcggactggggcagatgaatttacacggctatctggcgcga
gaaggcatcgcttatggttcgccggaagcactggatttcaccaatctctatttctatgcc
atcacctggcatgcactgcgtacctcgatgttgctggcacgcgaacgcggtgaaaccttc
gccgggttcaaacagtcacgctatgccagtggtgaatattttagccaatatctgcaaggg
aactggcagccgaaaacggcgaaagttggcgaactgtttacccgtagcggtattacgtta
cctacccgtgagatgtgggcgcagctgcgcgacgacgtgatgcgctacggcatatacaac
cagaatcttcaggcggtgccgccaaccggttctatctcttatatcaaccatgctacgtcg
agtattcatccgattgtggcgaaagtagagatacgcaaagagggcaaaacaggacgcgtt
tactaccctgccccgtttatgactaacgagaatctggcgctgtatcaggacgcttacgaa
attggcgcagaaaagatcatcgacacctacgcggaagcgactcgccatgtcgatcagggg
ctgtcgctgacgctttttttccccgataccgccaccactcgcgatatcaacaaagcgcag
atttacgcctggcgcaagggtatcaaaacgctctattacatccgcctgcgtcagatggcg
ctggaaggcactgaaattgaaggctgcgtctcctgtgcactttaa

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