Escherichia coli O157 H7 EDL933 (EHEC): Z3835
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Entry
Z3835 CDS
T00044
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase = FGAM synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ece
Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00230
Purine metabolism
ece01100
Metabolic pathways
ece01110
Biosynthesis of secondary metabolites
Module
ece_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ece00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Z3835 (purL)
Enzymes [BR:
ece01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Z3835 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AAG57671
UniProt:
Q8XA46
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Position
complement(3481878..3485765)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
XLAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgctcataactgcgggcta
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagttgtttgcccaccatcaaccgactccggttaccagc
gttgatttgctggggcagggccgtcaggcgctgatcgacgctaacctgcgtcttggcctg
gmtctggcggaagatgaaattgactatctgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgagctgtatatgttcgctcaggcgaactctgagcactgccgccacaaa
atttttaatgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaatactttcgaaaccacgccagatcacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcgaagccgaaagcgggtttggttggtttctccgtttccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcactgaatggctacttccgtacttatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaaactggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggagcggcgtcttccatggcgtcaggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgtcggcgctggcggtctttctaacgcgatgccggaactggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatattctaagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcaatta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcaccctacgcggtgattggtgaagcg
accgaagaactgcatctttctctgcacgatcgtcattttgataatcagccgatcgatctg
ccgctggacgtcctgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaagggcgatgcgctggtccgtgaagggatcaccattgcagacgcggtgaaacgcgta
ctgcatttgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagccgtg
ggcgaagagctttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccgcagctttct
accgaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagttgctg
gcgtatcacgaccgctctgatggcggtctgctggtaacgctggcggaaatggcctttgct
ggtcattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtcattcaggttcgtgccgctgaccgtgaagcggtcgag
tccgtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcactacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggagcatcaggcgaaatcaaacgacgccgatccgggcctgaatgtgaaa
ctgtcgtttgatatcaacgaagatgtggcagcaccgtatattgccactggcgcacgtccg
aaagttgctgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgctatcgacgtgcatatgagcgacctgctggctggacgcacg
ggcctggaggatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcttggttgaagtgacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaacggtattacggcggtcacgactgaaagcggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatcctgaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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