| Entry |
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| Symbol |
thrA
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| Name |
(GenBank) aspartokinase/homoserine dehydrogenase I
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| KO |
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| Organism |
ecf Escherichia coli O157:H7 EC4115 (EHEC)
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| Pathway |
| ecf00260 | Glycine, serine and threonine metabolism |
| ecf00270 | Cysteine and methionine metabolism |
| ecf01110 | Biosynthesis of secondary metabolites |
| ecf01120 | Microbial metabolism in diverse environments |
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| Module |
| ecf_M00016 | Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine |
| ecf_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
| ecf_M00018 | Threonine biosynthesis, aspartate => homoserine => threonine |
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| Brite |
KEGG Orthology (KO) [BR:ecf00001]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ECH74115_0003 (thrA)
00270 Cysteine and methionine metabolism
ECH74115_0003 (thrA)
00300 Lysine biosynthesis
ECH74115_0003 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ECH74115_0003 (thrA)
Enzymes [BR:ecf01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ECH74115_0003 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ECH74115_0003 (thrA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
360..2816
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| AA seq |
818 aa
MLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALP
NISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAAL
ICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIPAD
HMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPD
ARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRDED
ELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISFCV
PQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAALAR
ANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGALLE
QLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVK
EYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRK
FLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLARE
MGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANL
SQLDDLFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYS
HYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV |
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| NT seq |
2457 nt +upstreamnt +downstreamnt
gtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgggttgccgat
attctggaaagcaatgccaggcaggggcaggtggccaccgtcctctctgcccccgccaaa
atcaccaaccacctggtggcgatgattgaaaaaaccattagcggccaggatgctttaccc
aatatcagcgatgccgaacgtatttttgccgaacttctgacgggactcgccgccgcccag
ccgggattcccgctggcgcaattgaaaactttcgtcgaccaggaatttgcccaaataaaa
catgtcctgcatggcattagtttgttagggcagtgcccggatagcattaacgctgcgctg
atttgccgtggcgagaaaatgtcgatcgccattatggccggcgtattagaagcgcgcggt
cacaacgttaccgttatcgatccggtcgaaaaactgctggcagtggggcattacctcgaa
tctactgtcgatattgcagagtccacccgccgtattgcggcaagtcgtattccggctgat
cacatggtgctgatggcaggtttcaccgccggtaatgaaaaaggcgaactggtggtactt
ggacgcaacggttccgactactccgcggcggtgctggctgcctgtttacgcgccgattgt
tgcgagatttggacggacgttgacggggtatatacctgcgacccgcgtcaggtgcccgat
gcgaggttgttgaaatcgatgtcctaccaggaagcgatggagctttcctacttcggcgct
aaagttcttcacccccgcaccattacccccatcgcccagttccagatcccttgcctgatt
aaaaataccggaaatcctcaagctccaggtacgctcattggtgccagtcgtgatgaagac
gaattaccggtcaagggcatttccaatctgaataatatggcaatgttcagcgtttccggc
ccggggatgaaaggaatggtcggcatggcggcgcgcgtctttgctgcaatgtcacgcgcc
cgtatttccgtggtgctgattacgcaatcatcttccgaatacagtatcagtttctgcgtt
ccgcaaagcgactgtgtgcgagctgaacgggcaatgcaggaagagttctacctggaactg
aaagaaggcttactggagccgctggcggtgacggaacggctggccattatctcggtggta
ggtgatggtatgcgcaccttgcgtgggatctcggcgaaattctttgccgcgctggcccgc
gccaatatcaacattgtcgctattgctcagggatcttctgaacgctcaatctctgtcgtg
gtaaataacgatgatgcgaccactggcgtgcgcgttactcatcagatgctgttcaatacc
gatcaggttatcgaagtgtttgtgattggcgtcggtggcgttggcggtgcgctgctggag
caactgaagcgtcagcaaagctggttgaagaataaacatatcgacttacgtgtctgcggt
gttgctaactcgaaggctctgctcaccaatgtgcatggcctaaatctggaaaactggcag
gaagaactggcgcaagccaaagagccgtttaatctcgggcgcttaattcgcctcgtgaaa
gaatatcatctgctgaacccggtcattgttgactgcacctccagccaggcagtggcggat
caatatgccgacttcctgcgcgaaggtttccacgttgtcacgccgaacaaaaaggccaac
acctcgtcgatggattactaccatctgttgcgtcatgcggctgaaaaatcgcggcgtaaa
ttcctctatgacaccaacgttggggctggattaccggttattgagaacctgcaaaatctg
ctcaatgctggtgatgaattgatgaagttctccggcattctttcaggttcgctttcttat
atcttcggcaagttagacgaaggcatgagtttctccgaggcgactacgctggcgcgggaa
atgggttataccgaaccggatccgcgagatgatctttctggtatggatgtagcgcgtaaa
ctattaattctcgctcgtgaaacgggacgtgaactggagctggcggatattgaaattgaa
cctgtgctgcccgcagagtttaacgctgagggtgatgttgccgcttttatggcgaatctg
tcacagctcgacgatctctttgccgcgcgcgtggcgaaggcccgtgatgaaggaaaagtt
ttgcgctatgttggcaatattgatgaagatggcgtctgccgcgtgaagattgccgaagtg
gatggtaatgatccgctgttcaaagtgaaaaatggcgaaaacgccctggccttttatagc
cactattatcagccgctgccgttggtgctgcgcggatatggtgcgggcaatgacgttacc
gctgccggtgtctttgccgatctgctacgtaccctctcatggaagttaggagtctga |
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