Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_0079
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Entry
ECH74115_0079 CDS
T00778
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecf
Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00290
Valine, leucine and isoleucine biosynthesis
ecf00660
C5-Branched dibasic acid metabolism
ecf01100
Metabolic pathways
ecf01110
Biosynthesis of secondary metabolites
ecf01210
2-Oxocarboxylic acid metabolism
ecf01230
Biosynthesis of amino acids
Module
ecf_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ECH74115_0079 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECH74115_0079 (leuC)
Enzymes [BR:
ecf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ECH74115_0079 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ECH74115_0079 (leuC)
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
ACI36136
UniProt:
B5YZA8
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Position
complement(84052..85452)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGILLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaat
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctacccagactaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgaactgtatgacctg
aatcacccctatcaagggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgtgcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgttggcaattatcggtaaaaccggtagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcggatgaccctgtgc
aatatggcaatcgaaatgggcgcgaaagccggtctggttgcacctgacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactttgcag
gcagaagagatttcaccgcaggtcacctggggaactaacccaggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgttggcctatatggggctgaaaccgggtattctgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgcaccaactcacgtattgaagatttacgcgcggcggcggaa
atcgccaaagggcggaaagtcgcgccaggcgtacaggcgctggtggttcccggctctggt
ccggtaaaagcgcaggcggaagcagaaggtctggataaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgtcaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggccatttcgcc
gacattcgcaacattaaataa
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