Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_0081 Help Entry ECH74115_0081     CDS       T00778                                  Symbol leuA Name (GenBank) 2-isopropylmalate synthase   KO K01649   2-isopropylmalate synthase [EC:2.3.3.13] Organism ecf  Escherichia coli O157:H7 EC4115 (EHEC) Pathway ecf00290   Valine, leucine and isoleucine biosynthesis ecf00620   Pyruvate metabolism ecf01100   Metabolic pathways ecf01110   Biosynthesis of secondary metabolites ecf01210   2-Oxocarboxylic acid metabolism ecf01230   Biosynthesis of amino acids Module ecf_M00432   Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate Brite KEGG Orthology (KO) [BR:ecf00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     ECH74115_0081 (leuA)   09105 Amino acid metabolism    00290 Valine, leucine and isoleucine biosynthesis     ECH74115_0081 (leuA) Enzymes [BR:ecf01000]  2. Transferases   2.3  Acyltransferases    2.3.3  Acyl groups converted into alkyl groups on transfer     2.3.3.13  2-isopropylmalate synthase      ECH74115_0081 (leuA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HMGL-like LeuA_dimer HCS_D2 IPMS_D2 Motif Other DBs NCBI-ProteinID:  ACI37329 UniProt:  B5YZB0 LinkDB All DBs Position complement(86546..88117) Genome browser AA seq 523 aa AA seqDB search MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL ATDIVESSAKAMVHVLNNIWRATEVEKELQRKAQHNENNKETV NT seq 1572 nt NT seq  +upstreamnt  +downstreamnt atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt gacgtgatggaagtcgggttccccgtctcttcgccgggtgattttgaatcagtgcaaacc atcgctcgccaggttaaaaacagccgtgtatgcgcgttagctcgctgcgtggagaaagat atcgacgtggcggccgaatccctgaaagtcgccgaagccttccgtattcatacctttatt gccacttcgccaatgcacatcgccaccaagctgcgcagcacgctggacgaggtgatcgaa cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc gaagatgccgggcgtacacccattgccgatctggcgcgagtggtcgaagcggcgattaat gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc gccggaatcattagcggcctgtatgaacgcgtgcctaacatcgacaaagccattatttcc gtacatacccacgacgatttgggcctggcggtcggcaactcactggcggcggtacatgcc ggtgcacgccaggtggaaggtgcaatgaacgggatcggcgagcgtgccggtaactgttcc ctggaagaagtcatcatggcgattaaagttcgtaaggatattctcaacgtccacaccgcc attaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatccac caggatggcgtgctgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc atggatgagatggggtataaagaaagtgaatataatttagacaatttgtacgacgccttc ctcaagctggcggacaaaaaaggtcaggtgtttgattacgatctggaggcgctggccttc atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtct ggctctaacgatatcgccaccgccgccgtcaaactggcctgcggcgaagaagtcaaagca gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcgattaaccgcatcact gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg ctgggtcaggtggatattgtcgccaactacaacggtcgccgcttccacggcgtcggcctg gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtacttaacaatatctgg cgtgccacagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag gaaaccgtgtga

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