Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_3455
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Entry
ECH74115_3455 CDS
T00778
Symbol
folC
Name
(GenBank) tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ecf
Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00790
Folate biosynthesis
ecf01100
Metabolic pathways
ecf01240
Biosynthesis of cofactors
Module
ecf_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ecf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
ECH74115_3455 (folC)
Enzymes [BR:
ecf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
ECH74115_3455 (folC)
6.3.2.17 tetrahydrofolate synthase
ECH74115_3455 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ACI37643
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Position
complement(3199479..3200747)
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVCYTERVRVQGQELPESAHTASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKTLPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgagcgcgtgagccaggtcgcggcg
cgtcttggcgttctgaaaccagcgccatttgtgtttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcgcctcatctggtgtgttataccgagcgcgtacgtgtgcagggtcaggaattg
ccggaatcggcccacaccgcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaaacaggcacaactt
gacgtggtgattctggaagtagggctgggcggtcgtctggacgcaaccaatattgtcgac
gccgatgtcgcggtagtaaccagtattgcgctggatcataccgactggctggggccagat
cgcgaaagtattggtcgcgagaaagcaggcatctttcgcagcgaaaaaccggcaattgtc
ggtgagccggaaatgccttctaccattgctgatgtggcgcaggaaaaaggtgcactgtta
caacgtcggggcgttgagtggaactattccgtcaccgatcatgactgggcgtttagcgat
gctcacggcacgctggaaaacctgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaggtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccgggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggcgtatgaaaacgcta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gttgcgcaggcatgggatgccgcaatggcggacgctaaagcggaagacaccgtgctggtg
tgtggttcgttccacacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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