Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_5205
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Entry
ECH74115_5205 CDS
T00778
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
ecf
Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00290
Valine, leucine and isoleucine biosynthesis
ecf00770
Pantothenate and CoA biosynthesis
ecf01100
Metabolic pathways
ecf01110
Biosynthesis of secondary metabolites
ecf01210
2-Oxocarboxylic acid metabolism
ecf01230
Biosynthesis of amino acids
Module
ecf_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
ecf_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
ecf00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECH74115_5205 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ECH74115_5205 (ilvD)
Enzymes [BR:
ecf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ECH74115_5205 (ilvD)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ACI36421
UniProt:
B5YY20
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Position
4850020..4851870
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHSDRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQISFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctgcgcgatctcggtaaactggtc
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggattgccatgggccacggggggatgctttattcactgccatctcgcgaactgatc
gctgattccgttgagtatatggtcaacgcccactgcgccgacgccatggtctgcatctct
aactgtgacaaaatcaccccggggatgctgatggcttccctgcgtctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatc
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtatctgactcccag
agcgatcaggttgaacgttccgcatgcccaacctgcggttcctgctccgggatgtttacc
gctaactcaatgaactgcctgaccgaagcgctgggtctgtcgcagccgggcaacggctcg
ctgctggcaacccactctgaccgtaagcagctgttcctcaatgctggtaaacgcattgtt
gaattgaccaaacgttactacgagcaaaacgacgaaagtgcactgccccgcaatattgct
agcaaagcggcgtttgaaaatgccatgacgctggatatcgcgatgggtggatcgactaac
accgtacttcacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgataagctttcccgcaaggttccgcagttatgcaaagtcgcgccgagcacccaaaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgagctggat
cgtgcggggttactgaaccgtgatgtgaaaaacgtacttggcctgacgttgccgcaaacg
ctggaacaatacgacgttatgctgacccaggatgacgcggtaaaaaatatgttccgcgcc
ggccctgcgggtatccgtaccacccaggcattctcgcaagattgccgttgggatacgctg
gacgacgatcgcgccaatggctgtatccgctcgctggaacacgcctatagcaaagacggc
ggcctggcggtgctctacggtaatttcgcggaaaacggctgcatcgttaaaactgcgggc
gtcgatgacagcatcctcaaattcaccggcccggcgaaagtgtacgaaagccaggacgac
gcggtagaagcgattctcggcggtaaagttgtcgccggagatgtggtagtaattcgctat
gaaggcccaaaaggtggtccggggatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatggggctcggtaaagcctgtgcgctgatcaccgacggtcgtttctctggcggcacc
tctggcctttctatcggccacgtctcaccggaagcggcaagcggcggcagcattggcctg
attgaagacggcgacctgatcgccatcgacattccgaaccgtggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcggggtgacaaagcctgg
acgccgaaaaatcgtgaacgtcagatctcctttgccctgcgtgcttatgccagcctggca
accagcgccgacaaaggcgcggtgcgcgataaatcgaaactggggggttaa
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