Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_5270
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Entry
ECH74115_5270 CDS
T00778
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
ecf
Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00270
Cysteine and methionine metabolism
ecf00450
Selenocompound metabolism
ecf01100
Metabolic pathways
ecf01110
Biosynthesis of secondary metabolites
ecf01230
Biosynthesis of amino acids
Module
ecf_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ecf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ECH74115_5270 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ECH74115_5270 (metE)
Enzymes [BR:
ecf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
ECH74115_5270 (metE)
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
ACI36187
UniProt:
B5YY78
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Position
4912477..4914738
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AA seq
753 aa
AA seq
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MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP
VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGKVKGEQFDR
LSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNVWRAD
LTEKYVQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLR
DALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRAR
FKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYA
QSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgacaatattgaatcacaccctcggtttccctcgcgttggcctgcgtcgcgagctgaaa
aaagcgcaagagagttattgggcggggaactccacgcgtgaagaactgctggcggtaggg
cgtgaattgcgtgctcgtcactgggatcaacaaaagcaagcgggtatcgacctgctgccg
gtgggcgattttgcctggtacgatcatgtactgaccaccagtctgctgctgggtaacgtt
ccggcgcgtcatcagaacaaagatggttcggtagatatcgacaccctgttccgtattggt
cgtggacgtgcgccgactggcgaacctgcggcggcagcggaaatgaccaaatggtttaac
accaactatcactacatggtgccggagttcgttaaaggccaacagttcaaactgacctgg
acgcagctgctggacgaagtggacgaggcgctggcgctgggccacaaggtgaaacctgtg
ctgctggggccgattacctggctgtggctggggaaagtgaaaggtgaacagtttgaccgc
ctgagcctgctgaacgacattctgccggtttatcagcaagtgctggcagaactggcgaaa
cgtggcatcgagtgggtacagattgatgaacccgcgctggtactggaactaccacaggcg
tggctggacgcatacaaacccgcttacgacgcgctccagggacaggtgaaactgctgctg
accacctattttgaaggcgtaacgccaaatctcgacacgattactgcgctgcctgttcag
gggctgcatgtggaccttgtacatggtaaagatgacgttgttgaactgcacaagcgcctg
ccttctgactggctgctgtctgcgggtctgatcaatggtcgtaacgtctggcgcgccgat
cttactgagaaatatgtgcaaattaaggacattgtcggcaaacgtgatttgtgggtggca
tcttcctgctcgttgctgcacagccccatcgacctgagcgtggaaacgcgtcttgatgca
gaagtgaaaagctggtttgccttcgccctacaaaaatgccatgaactggcactgctgcgc
gatgcgctgaacagtggtgacacggcagctctggcagagtggagcgccccaattcaggcg
cgtcgtcactctactcgtgtacataatccggcggtagaaaagcgtctggcggcgatcacc
gcccaggacagccagcgtgcgaatgtctatgaagtgcgtgctgaagcccagcgtgcgcgt
tttaaactgccagcgtggccgaccaccacgattggttccttcccgcaaaccacggaaatt
cgtaccctgcgtctggatttcaaaaagggcaatctcgacgccaataactaccgcacgggc
attgcggaacatatcaggcaggccattgttgaacaggaacgtttgggactggatgtgctg
gtacatggcgaggccgagcgtaatgacatggtggaatactttggcgagcacctcgacggg
tttgtctttacgcaaaacggttgggtacagagctacggttcccgctgcgtgaagccaccg
attgttattggtgacgttagtcgcccggcaccgattaccgtggagtgggcgaagtatgcg
caatctatgactgataaaccggtgaaagggatgctgactggcccggtgaccattctctgc
tggtcgttcccgcgtgaagatgtcagccgtgaaaccatcgccaaacaaattgcgctggcg
ctgcgtgatgaagtggcggacctggaagccgcaggaattggcatcatccagattgatgaa
ccggcgctgcgcgaaggtttaccgctgcgtcgtagcgactgggatgcatatctccagtgg
ggcgtggaggccttccgtatcaacgccgccgtggcgaaagatgacacacaaatccacact
cacatgtgttattgcgagttcaacgacatcatggattcgattgcggcactggacgcagac
gtcatcaccatcgaaacctcgcgttctgacatggagttgctggagtcgttcgaagagttt
gattatccgaatgaaatcggtccaggcgtctatgacattcactcgccaaacgtaccgagc
gtggaatggattgaagccttgctgaagaaagcggcaaaacgcattccggcagagcgcctg
tgggtcaacccggactgtggcctgaaaacgcgcggctggccagaaacccgcgcggcactg
gcgaacatggtgcaggcggcgcagaacttgcgtcgggggtaa
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