KEGG   Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_0462
Entry
E2348C_0462       CDS       T00796                                 
Symbol
folD
Name
(GenBank) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
ecg  Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00670  One carbon pool by folate
ecg00720  Other carbon fixation pathways
ecg01100  Metabolic pathways
ecg01120  Microbial metabolism in diverse environments
ecg01200  Carbon metabolism
ecg01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:ecg00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    E2348C_0462 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    E2348C_0462 (folD)
Enzymes [BR:ecg01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     E2348C_0462 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     E2348C_0462 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: CAS08010
UniProt: B7UKK6
LinkDB
Position
complement(514777..515643)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcgccaggactggccgttgtgctg
gtgggtagcaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttatgacctcccggaaaccaccagcgaagcggagctgctg
gagcttatcgatgcgctgaatgccgacaacaccattgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgtattcatccggacaaagacgtg
gacggtttccatccttacaacgtcggtcgtctgtgccagcgcgcgccacgtctgcgtccc
tgtaccccgcgcggtatcgtcacgctgcttgagcgttacaacattgataccttcggcctt
aacgccgtggtgattggcgcatcgaatatcgtcggtcgcccaatgagcatggaactgctg
ctggcaggttgcaccaccaccgtgactcaccgtttcactaaaaatctgcgtcaccacgta
gaaaatgccgatctactgatcgttgccgtcggcaagccgggctttattcctggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtctggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccg
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacagggtgagtaa

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