Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_2834
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Entry
E2348C_2834 CDS
T00796
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecg
Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00230
Purine metabolism
ecg01100
Metabolic pathways
ecg01110
Biosynthesis of secondary metabolites
Module
ecg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
E2348C_2834 (purL)
Enzymes [BR:
ecg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
E2348C_2834 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CAS10382
UniProt:
B7UGZ7
LinkDB
All DBs
Position
complement(2921319..2925206)
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AA seq
1295 aa
AA seq
DB search
MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEGFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgtggcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatttgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgaactgtatatgtttgcccaggcgaattccgagcactgccgccacaaa
atttttaacgccgactgggttatcgatggtgaacagcagccgaaatcgctatttaagatg
atcaaaaacaccttcgaaaccacgccggatcacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccggacgtggcgcaaagccgaaagccggtctggttggtttctccgtatccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaaacctgagcgcattgtt
accgcgctggacatcatgaccgaaggcccgctgggcggtgcggcgtttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcatctggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcaccctacgcggtgattggtgaagcg
accgaagaactgcatctttctttgcacgatcgtcattttgataatcagccgattgatcta
ccgctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgcgtg
ctgcatctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactatggcgaagcgatggcaattggcgaacgt
gcgccagttgcgctgctggatttcgccgcttctgcccgtctggcagtcggtgaagcgcta
accaacatcgccgcaacacaaattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgataccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgttgtcgctg
gtgatttccgcatttgcccgcgtggaagatgtacgtcacaccattacgccgcagctttct
accgaagataacgcactgttgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcactggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtt
gcccaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgtggcattgacgcggatatcgccactctgggtgacgatcgcctggctgcattg
tttagcgaagaactgggtgcggtgattcaggtgcgagccgctgaccgtgaagccgttgaa
gcggtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtatttagcgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgctgaccaggagcaccaggcgaaatcaaacgacgccgatccgggcctgaatgtaaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtttattgccactggcgcgcgcccg
aaagttgccgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgctatcgacgtgcatatgagcgatctgctggctggacgcacg
ggcctggagggtttccacgccctggtcgcgtgcggtggtttttcctacggtgatgtgctg
ggcgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccaggtagcgagttgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagtctggtagaagtaacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcagatgccgattgctgtctctcacggtgaagggcgc
gttgaagtgcgcgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttca
ccgaacggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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