Echinicola soli: FKX85_09520
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Entry
FKX85_09520 CDS
T06084
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
echi
Echinicola soli
Pathway
echi00260
Glycine, serine and threonine metabolism
echi00261
Monobactam biosynthesis
echi00270
Cysteine and methionine metabolism
echi00300
Lysine biosynthesis
echi01100
Metabolic pathways
echi01110
Biosynthesis of secondary metabolites
echi01120
Microbial metabolism in diverse environments
echi01230
Biosynthesis of amino acids
Module
echi_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
echi_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
echi00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FKX85_09520 (thrA)
00270 Cysteine and methionine metabolism
FKX85_09520 (thrA)
00300 Lysine biosynthesis
FKX85_09520 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FKX85_09520 (thrA)
Enzymes [BR:
echi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FKX85_09520 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FKX85_09520 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
NAD_binding_3
ACT
Motif
Other DBs
NCBI-ProteinID:
QDH79257
UniProt:
A0A514CHF9
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All DBs
Position
2347347..2349794
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AA seq
815 aa
AA seq
DB search
MKIIKFGGSSIANYENIQKVFSIVEQKSGKEAFALVFSAFGGVTEQLLQCANIAQQSEES
YHTILQELEKRHLEIAKKLVPVQQQSTALTFVKVRFNELGDLFHGIYLIKECSNRTMDYV
LSFGERLSNFILAAGLQAKGISTTYVDARDLVKTDGRFGHAKVNFKSTNKLIQSYFEKHE
GIKVITGFIGSTDKGETTTVGRSGSDYTASIFAAALGAEQVEIWTDVSGVMTADPRLVYT
AFTIPQLSYNEAMELSHFGAKVVFPATMQPAMKEDIPIYIKNTFKPEEEGTRISKESGEG
KIIKGISSMDNISILNVQGPGLVEVVGVSQRFFGTLANNGINIILISQASSEHSICVAIA
SKDASRAKSVIEEEFRYEIQSGEMAEIEVVPDMAVIAVVGENMQHNPGASGRMFQALGRN
NVNVAAIAQGSSELNISAVITQADLQKALNALHEAFFLSDYKVLHVFLVGVGLIGKALTK
MINNQLGKLQEENMLDIQIHGMANSRYMKFHEDGFDLATVGPPDENDEPMDMGKFIGTMT
EMNFSNSVFVDCTASQDVADIYEQILDSKVGIVTPNKKANSGPLDTYKKLKKLAGQRGVR
FFYETNVAAGLPVINTLQDLMLSGDHVHRIEAVLSGSMNYIFSELEKGMPFSEVVAQAKE
KGYTEPDPRDDLSGMDVARKILILGREAGQDLHFEDVDIQSMVPEDCEDAASVPEFFEKL
QKHDGHFQQLLDEAKAKGEKLRFMATLENGKAKVGLNSLDSEHPFYTLKGSDNMILFTTE
RYNDFPMIVRGPGAGADVTAAGVFADIIRLGNYSR
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatcataaaattcggaggatcatccatcgcaaattatgagaacatccaaaaggtg
ttttccatagtggagcagaagtcaggaaaggaagcgtttgccctggtgttttcagctttt
ggtggagtcactgaacaattgctacaatgtgccaatatcgcccagcaaagtgaggaaagt
taccataccatccttcaggaacttgaaaaaaggcacttagagattgccaagaagctagtg
ccggtgcagcagcaatccaccgcactgacatttgtgaaggtccgattcaatgaattgggc
gacttgttccacgggatctacttgataaaagaatgttctaataggacaatggactatgtc
ctcagctttggagagcggctgtccaattttattttggcagcaggccttcaggccaaaggt
atatccaccacctatgtggatgcccgtgacctggtaaaaacagatggtcggtttggtcat
gccaaggtgaattttaaaagcaccaataagctgatccaaagttattttgaaaagcacgag
gggatcaaggtgatcaccggttttattggctccaccgataagggtgaaaccaccacagtg
ggcagaagtgggtccgattatacagcatctatttttgccgcggcgcttggagcggagcag
gtagagatatggacggatgtttccggtgtgatgacggcagatccaagattagtgtatacc
gcatttacgattcctcagctgagctataacgaggccatggaactttcgcactttggggca
aaagtagtgttcccggcgaccatgcagccggccatgaaggaggatattccgatatacatc
aaaaatacgtttaagcctgaggaagaaggcacacggatcagcaaagagtcaggagagggg
aaaatcatcaagggaatttcctctatggacaatatctcgatcctcaacgtacagggacca
ggattggtagaggtcgtaggggtgagccagcgtttcttcggcactttggccaacaatggc
atcaatatcatcctgatcagtcaggcttcttctgagcatagcatttgtgtggcgattgct
tcaaaggatgccagtcgagccaagtctgtgatcgaggaggagttcaggtacgaaatccaa
agtggtgagatggccgagatcgaggtggttcctgatatggcggtcatcgccgtggtgggc
gaaaatatgcagcataacccaggtgccagtggacggatgttccaggcgttgggcagaaat
aatgtcaatgtggccgccatcgcccagggaagctccgaactaaatatctcggcagtgatc
acgcaggcagacttgcaaaaagccctgaatgcattgcatgaggcattcttcctgtccgat
tacaaggtcctccatgtctttttggtaggagtgggcttgataggcaaggctttgaccaaa
atgatcaacaaccagcttggaaagctgcaagaggaaaatatgctggacatccaaatccat
ggaatggccaattcccgctatatgaagttccatgaagatggttttgatctggcgacagtg
gggccaccggatgaaaatgatgagccgatggacatgggtaagtttattggcacgatgaca
gagatgaatttttccaattctgtttttgtagactgtaccgccagtcaggatgtagcggat
atctatgagcaaatccttgattccaaagtaggtatcgtaaccccaaataagaaagccaac
tcgggtcctttggatacctataagaaacttaaaaaattggctggccaacgtggcgtaagg
tttttctatgagaccaatgtggccgctggtctgccggtgatcaataccctgcaggacttg
atgttaagtggcgatcatgtgcaccgcatcgaagccgtgctgagtgggtcgatgaactat
atattcagcgaactggaaaaaggcatgccgttcagcgaagtggtggcccaggccaaagaa
aaaggctataccgagccagatccaagggatgatttgagcggtatggatgtggcgcgcaaa
atcctgatccttggtcgtgaagccgggcaggacctgcactttgaagatgtggatatccag
agtatggtaccggaggattgtgaggatgcggcttctgtcccggagtttttcgagaagttg
caaaagcatgacggtcatttccagcagctcttggatgaagccaaagccaaaggtgaaaag
ctccgttttatggcgactttagagaatggaaaggccaaagtagggctgaattccctggat
agtgagcatccgttctatacccttaagggcagtgataacatgatattgtttaccacagag
cgctataatgacttcccaatgatcgtaagaggtcctggggcaggtgcagatgtgactgca
gccggggtatttgccgatattatcaggctaggaaattattcaagatga
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