Enterobacter chuandaensis: RQP59_03770
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Entry
RQP59_03770 CDS
T11050
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
echu Enterobacter chuandaensis
Pathway
echu00260
Glycine, serine and threonine metabolism
echu00261
Monobactam biosynthesis
echu00270
Cysteine and methionine metabolism
echu00300
Lysine biosynthesis
echu01100
Metabolic pathways
echu01110
Biosynthesis of secondary metabolites
echu01120
Microbial metabolism in diverse environments
echu01230
Biosynthesis of amino acids
Module
echu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
echu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
echu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
echu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
RQP59_03770 (thrA)
00270 Cysteine and methionine metabolism
RQP59_03770 (thrA)
00300 Lysine biosynthesis
RQP59_03770 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
RQP59_03770 (thrA)
Enzymes [BR:
echu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
RQP59_03770 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
RQP59_03770 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
WNS38693
UniProt:
A0AA96RT73
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All DBs
Position
773049..775511
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFADLLQGLAEAQPGFPLAQLKSFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHNVTVINPVEKLLAAGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASSD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQADCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLIGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSRALLTNVHGLNLENWQAELEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPAEFDSSGDVSAFMA
NLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggagagcaacgccaggcaggggcaggttgcgaccgtgctctctgccccg
gcaaaaatcacgaaccatctggtggcgatgattgaaaaaaccatcggtggccaggatgca
ctcccgaacatcagcgacgcagagcgtatcttcgctgacttactgcaagggctggcagag
gctcagcctggtttcccgctcgctcagctgaagtccttcgttgagcaggaattcgcgcaa
atcaaacacgtcctgcacggcatcagcctcctcggccagtgcccggacagcatcaacgcg
gcgctgatctgccgtggtgagaagctctcgatcgccatcatggcaggcgtgctggaagcg
cgcggccacaatgttaccgtgattaatccggttgagaaattgctggcggcaggtcactac
ctcgaatccaccgttgatattgccgaatcaacccgccgtatcgccgcgagcaaaatcccg
tctgaccacatgatcctgatggccggattcactgccggaaatgagaagggcgagctggtg
gtgctgggccgtaacggctctgactactccgccgccgtgctggctgcctgcttacgcgcg
gactgctgtgagatctggactgacgtggacggcgtttatacctgtgacccgcgccaggtg
ccggacgccaggctgctgaagtcgatgtcttaccaggaggcgatggagctttcctacttc
ggcgccaaagtgcttcacccgcgtaccatctccccgattgcccagttccagatcccttgc
ctgattaaaaataccggtaacccgcaggcgccgggcacgctgattggcgccagttctgat
gaagatggcctgccggtgaaaggtatttccaacctgaacaacatggcgatgttcagcgtc
tcaggtccagggatgaaagggatggtcggcatggcggcacgcgtttttgcggccatgtca
cgcaacggtatctccgtggtgctgatcacgcagtcctcttccgagtacagcatcagcttc
tgcgtgccgcaggctgactgcctgcgcgcccgccgcgcgctggaagaagagttctatctg
gagctgaaagaagagctgctggagccgctttccattcaggagcgtctggcggtaatctcc
gtcgtaggcgacggaatgcgcacgctgcgcggcatttccgccaagttctttgccgcgctg
gcccgcgccaatattaatatcgtggcgattgctcagggctcgtccgaacgttcaatctct
gttgtcgtggataatgatgacgccaccaccggcgtgcgcgtggtgcaccagatgctgttc
aacaccgatcaggtgatcgagctgttcctgattggcgtgggcggcgtcggtggcgcattg
ctggagcaggtgaagcgccagcaggagtggcttaagaagaagcatatcgatctgcgcgtc
tgcgggattgccaactccagagcgctgctgaccaacgttcacggccttaacctggagaac
tggcaggcggagctggaagaggcgaaagagccgttcaacctggggcgcctgatccgtctg
gtaaaagagtatcacctgcttaacccggtgattgttgactgtacctcgaaccaggcggtg
gccgaccagtatgccgacttcctgcgcgaaggcttccacgtggtgacgccgaataaaaag
gccaatacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcgcgc
cgcaagttcctgtacgacaccaacgtcggcgcggggctgccggttattgaaaacctgcaa
aacctgctcaacgcgggtgacgaactgcagcgtttctccggtattctctccggctccctg
tcgtttatcttcggcaagctggatgagggtatgagcctctcggaagccacccgcgctgcg
cgcgagctgggctacaccgagccggatccgcgtgacgatctttccggtatggacgtggcg
cgcaagctgctgattctggcgcgtgaaacgggccgcgagctggagctttccgacatcgtg
attgagcccgtgctgccagcagaatttgacagcagcggtgacgtcagcgcttttatggcg
aatttgccccagcttgacgatgcctttgccgcgcgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaatattgaagaagatggcgtatgccgggtgaagattgcc
gaagtggatggcaacgacccgctgtacaaagtcaaaaacggcgaaaacgccctcgcgttt
tacagccactattatcagccactgccgctggtgcttcgcggctatggcgcagggaacgat
gttacggcggcgggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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