Escherichia coli K-12 W3110: JW0031
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Entry
JW0031 CDS
T00068
Symbol
carB
Name
(GenBank) carbamoyl-phosphate synthase large subunit
KO
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00220
Arginine biosynthesis
ecj00240
Pyrimidine metabolism
ecj00250
Alanine, aspartate and glutamate metabolism
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01240
Biosynthesis of cofactors
Module
ecj_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
JW0031 (carB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
JW0031 (carB)
00220 Arginine biosynthesis
JW0031 (carB)
Enzymes [BR:
ecj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
JW0031 (carB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D3
MGS
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
ATPgrasp_Ter
CoA_binding_2
BamE
Motif
Other DBs
NCBI-ProteinID:
BAB96602
UniProt:
P00968
Structure
PDB
PDBj
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All DBs
Position
30817..34038
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AA seq
1073 aa
AA seq
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MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEM
ADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATA
DAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGG
IAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIP
RFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEA
LTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
ITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDT
AYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVN
CNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVP
VIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVL
GGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIME
HIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLI
EVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKF
PGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDL
AAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGR
RAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
NT seq
3222 nt
NT seq
+upstream
nt +downstream
nt
atgccaaaacgtacagatataaaaagtatcctgattctgggtgcgggcccgattgttatc
ggtcaggcgtgtgagtttgactactctggcgcgcaagcgtgtaaagccctgcgtgaagag
ggttaccgcgtcattctggtgaactccaacccggcgaccatcatgaccgacccggaaatg
gctgatgcaacctacatcgagccgattcactgggaagttgtacgcaagattattgaaaaa
gagcgcccggacgcggtgctgccaacgatgggcggtcagacggcgctgaactgcgcgctg
gagctggaacgtcagggcgtgttggaagagttcggtgtcaccatgattggtgccactgcc
gatgcgattgataaagcagaagaccgccgtcgtttcgacgtagcgatgaagaaaattggt
ctggaaaccgcgcgttccggtatcgcacacacgatggaagaagcgctggcggttgccgct
gacgtgggcttcccgtgcattattcgcccatcctttaccatgggcggtagcggcggcggt
atcgcttataaccgtgaagagtttgaagaaatttgcgcccgcggtctggatctctctccg
accaaagagttgctgattgatgagtcgctgatcggctggaaagagtacgagatggaagtg
gtgcgtgataaaaacgacaactgcatcatcgtctgctctatcgaaaacttcgatgcgatg
ggcatccacaccggtgactccatcactgtcgcgccagcccaaacgctgaccgacaaagaa
tatcaaatcatgcgtaacgcctcgatggcggtgctgcgtgaaatcggcgttgaaaccggt
ggttccaacgttcagtttgcggtgaacccgaaaaacggtcgtctgattgttatcgaaatg
aacccacgcgtgtcccgttcttcggcgctggcgtcgaaagcgaccggtttcccgattgct
aaagtggcggcgaaactggcggtgggttacaccctcgacgaactgatgaacgacatcact
ggcggacgtactccggcctccttcgagccgtccatcgactatgtggttactaaaattcct
cgcttcaacttcgaaaaattcgccggtgctaacgaccgtctgaccactcagatgaaatcg
gttggcgaagtgatggcgattggtcgcacgcagcaggaatccctgcaaaaagcgctgcgc
ggcctggaagtcggtgcgactggattcgacccgaaagtgagcctggatgacccggaagcg
ttaaccaaaatccgtcgcgaactgaaagacgcaggcgcagatcgtatctggtacatcgcc
gatgcgttccgtgcgggcctgtctgtggacggcgtcttcaacctgaccaacattgaccgc
tggttcctggtacagattgaagagctggtgcgtctggaagagaaagtggcggaagtgggc
atcactggcctgaacgctgacttcctgcgccagctgaaacgcaaaggctttgccgatgcg
cgcttggcaaaactggcgggcgtacgcgaagcggaaatccgtaagctgcgtgaccagtat
gacctgcacccggtttataagcgcgtggatacctgtgcggcagagttcgccaccgacacc
gcttacatgtactccacttatgaagaagagtgcgaagcgaatccgtctaccgaccgtgaa
aaaatcatggtgcttggcggcggcccgaaccgtatcggtcagggtatcgaattcgactac
tgttgcgtacacgcctcgctggcgctgcgcgaagacggttacgaaaccattatggttaac
tgtaacccggaaaccgtctccaccgactacgacacttccgaccgcctctacttcgagccg
gtaactctggaagatgtgctggaaatcgtgcgtatcgagaagccgaaaggcgttatcgtc
cagtacggcggtcagaccccgctgaaactggcgcgcgcgctggaagctgctggcgtaccg
gttatcggcaccagcccggatgctatcgaccgtgcagaagaccgtgaacgcttccagcat
gcggttgagcgtctgaaactgaaacaaccggcgaacgccaccgttaccgctattgaaatg
gcggtagagaaggcgaaagagattggctacccgctggtggtacgtccgtcttacgttctc
ggcggtcgggcgatggaaatcgtctatgacgaagctgacctgcgtcgctacttccagacg
gcggtcagcgtgtctaacgatgcgccagtgttgctggaccacttcctcgatgacgcggta
gaagttgacgtggatgccatctgcgacggcgaaatggtgctgattggcggcatcatggag
catattgagcaggcgggcgtgcactccggtgactccgcatgttctctgccagcctacacc
ttaagtcaggaaattcaggatgtgatgcgccagcaggtgcagaaactggccttcgaattg
caggtgcgcggcctgatgaacgtgcagtttgcggtgaaaaacaacgaagtctacctgatt
gaagttaacccgcgtgcggcgcgtaccgttccgttcgtctccaaagccaccggcgtaccg
ctggcaaaagtggcggcgcgcgtgatggctggcaaatcgctggctgagcagggcgtaacc
aaagaagttatcccgccgtactactcggtgaaagaagtggtgctgccgttcaataaattc
ccgggcgttgacccgctgttagggccagaaatgcgctctaccggggaagtcatgggcgtg
ggccgcaccttcgctgaagcgtttgccaaagcgcagctgggcagcaactccaccatgaag
aaacacggtcgtgcgctgctttccgtgcgcgaaggcgataaagaacgcgtggtggacctg
gcggcaaaactgctgaaacagggcttcgagctggatgcgacccacggcacggcgattgtg
ctgggcgaagcaggtatcaacccgcgtctggtaaacaaggtgcatgaaggccgtccgcac
attcaggaccgtatcaagaatggcgaatatacctacatcatcaacaccacctcaggccgt
cgtgcgattgaagactcccgcgtgattcgtcgcagtgcgctgcaatataaagtgcattac
gacaccaccctgaacggcggctttgccaccgcgatggcgctgaatgccgatgcgactgaa
aaagtaatttcggtgcaggaaatgcacgcacagatcaaataa
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