Escherichia coli K-12 W3110: JW0086
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Entry
JW0086 CDS
T00068
Symbol
murD
Name
(GenBank) UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
KO
K01925
UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:
6.3.2.9
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00470
D-Amino acid metabolism
ecj00550
Peptidoglycan biosynthesis
ecj01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
JW0086 (murD)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
JW0086 (murD)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ecj01011
]
JW0086 (murD)
Enzymes [BR:
ecj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.9 UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase
JW0086 (murD)
Peptidoglycan biosynthesis and degradation proteins [BR:
ecj01011
]
Precursor biosynthesis
Amino acid ligase
JW0086 (murD)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MurD-like_N
Mur_ligase_M
Mur_ligase_C
NAD_binding_7
Motif
Other DBs
NCBI-ProteinID:
BAB96656
UniProt:
P14900
Structure
PDB
PDBj
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Position
97087..98403
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AA seq
438 aa
AA seq
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MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLND
EWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVT
TLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNV
TEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHL
NHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGL
PHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYL
NGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQF
KNFEQRGNEFARLAKELG
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atggctgattatcagggtaaaaatgtcgtcattatcggcctgggcctcaccgggctttcc
tgcgtggactttttcctcgctcgcggtgtgacgccgcgcgttatggatacgcgtatgaca
ccgcctggcctggataaattacccgaagccgtagaacgccacacgggcagtctgaatgat
gaatggctgatggcggcagatctgattgtcgccagtcccggtattgcactggcgcatcca
tccttaagcgctgccgctgatgccggaatcgaaatcgttggcgatatcgagctgttctgt
cgcgaagcacaagcaccgattgtggcgattaccggttctaacggcaaaagcacggtcacc
acgctagtgggtgaaatggcgaaagcggcgggggttaacgttggtgtgggtggcaatatt
ggcctgcctgcgttgatgctactggatgatgagtgtgaactgtacgtgctggaactgtcg
agcttccagctggaaaccacctccagcttacaggcggtagcagcgaccattctgaacgtg
actgaagatcatatggatcgctatccgtttggtttacaacagtatcgtgcagcaaaactg
cgcatttacgaaaacgcgaaagtttgcgtggttaatgctgatgatgccttaacaatgccg
attcgcggtgcggatgaacgctgcgtcagctttggcgtcaacatgggtgactatcacctg
aatcatcagcagggcgaaacctggctgcgggttaaaggcgagaaagtgctgaatgtgaaa
gagatgaaactttccgggcagcataactacaccaatgcgctggcggcgctggcgctggca
gatgctgcagggttaccgcgtgccagcagcctgaaagcgttaaccacattcactggtctg
ccgcatcgctttgaagttgtgctggagcataacggcgtacgttggattaacgattcgaaa
gcgaccaacgtcggcagtacggaagcggcgctgaatggcctgcacgtagacggcacactg
catttgttgctgggtggcgatggtaaatcggcggactttagcccactggcgcgttacctg
aatggcgataacgtacgtctgtattgtttcggtcgtgacggcgcgcagctggcggcgcta
cgcccggaagtggcagaacaaaccgaaactatggaacaggcgatgcgcttgctggctccg
cgtgttcagccgggcgatatggttctgctctccccagcctgtgccagccttgatcagttc
aagaactttgaacaacgaggcaatgagtttgcccgtctggcgaaggagttaggttga
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