Escherichia coli K-12 W3110: JW1122
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Entry
JW1122 CDS
T00068
Symbol
icd
Name
(GenBank) isocitrate dehydrogenase, specific for NADP+
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00020
Citrate cycle (TCA cycle)
ecj00480
Glutathione metabolism
ecj00720
Other carbon fixation pathways
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01120
Microbial metabolism in diverse environments
ecj01200
Carbon metabolism
ecj01210
2-Oxocarboxylic acid metabolism
ecj01230
Biosynthesis of amino acids
ecj04146
Peroxisome
Module
ecj_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecj_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
JW1122 (icd)
09102 Energy metabolism
00720 Other carbon fixation pathways
JW1122 (icd)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
JW1122 (icd)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
JW1122 (icd)
Enzymes [BR:
ecj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
JW1122 (icd)
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Motif
Pfam:
Iso_dh
tRNA_synt_1c_R1
Motif
Other DBs
NCBI-ProteinID:
BAA35958
UniProt:
P08200
Structure
PDB
PDBj
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Position
1196700..1197950
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AA seq
416 aa
AA seq
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MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE
RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ
ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR
EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA
FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA
CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA
EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atggaaagtaaagtagttgttccggcacaaggcaagaagatcaccctgcaaaacggcaaa
ctcaacgttcctgaaaatccgattatcccttacattgaaggtgatggaatcggtgtagat
gtaaccccagccatgctgaaagtggtcgacgctgcagtcgagaaagcctataaaggcgag
cgtaaaatctcctggatggaaatttacaccggtgaaaaatccacacaggtttatggtcag
gacgtctggctgcctgctgaaactcttgatctgattcgtgaatatcgcgttgccattaaa
ggtccgctgaccactccggttggtggcggtattcgctctctgaacgttgccctgcgccag
gaactggatctctacatctgcctgcgtccggtacgttactatcagggcactccaagcccg
gttaaacaccctgaactgaccgatatggttatcttccgtgaaaactcggaagacatttat
gcgggtatcgaatggaaagcagactctgccgacgccgagaaagtgattaaattcctgcgt
gaagagatgggggtgaagaaaattcgcttcccggaacattgtggtatcggtattaagccg
tgttcggaagaaggcaccaaacgtctggttcgtgcagcgatcgaatacgcaattgctaac
gatcgtgactctgtgactctggtgcacaaaggcaacatcatgaagttcaccgaaggagcg
tttaaagactggggctaccagctggcgcgtgaagagtttggcggtgaactgatcgacggt
ggcccgtggctgaaagttaaaaacccgaacactggcaaagagatcgtcattaaagacgtg
attgctgatgcattcctgcaacagatcctgctgcgtccggctgaatatgatgttatcgcc
tgtatgaacctgaacggtgactacatttctgacgccctggcagcgcaggttggcggtatc
ggtatcgcccctggtgcaaacatcggtgacgaatgcgccctgtttgaagccacccacggt
actgcgccgaaatatgccggtcaggacaaagtaaatcctggctctattattctctccgct
gagatgatgctgcgccacatgggttggaccgaagcggctgacttaattgttaaaggtatg
gaaggcgcaatcaacgcgaaaaccgtaacctatgacttcgagcgtctgatggatggcgct
aaactgctgaaatgttcagagtttggtgacgcgatcatcgaaaacatgtaa
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