Escherichia coli K-12 W3110: JW2484
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Entry
JW2484 CDS
T00068
Symbol
purM
Name
(GenBank) phosphoribosylaminoimidazole synthetase
KO
K01933
phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.3.1
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00230
Purine metabolism
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
Module
ecj_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
JW2484 (purM)
Enzymes [BR:
ecj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
JW2484 (purM)
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Gene cluster
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Motif
Pfam:
AIRS_C
AIRS
Motif
Other DBs
NCBI-ProteinID:
BAA16387
UniProt:
P08178
Structure
PDB
PDBj
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Position
2619853..2620890
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AA seq
345 aa
AA seq
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MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVL
VSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAS
AVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDV
LIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKV
DVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVEHHEMYRTFNC
GVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
NT seq
1038 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgataaaacctctcttagctacaaagatgccggtgttgatattgacgcgggtaat
gctctggttggaagaatcaaaggcgtagtgaagaaaacgcgtcgtccggaagtgatgggc
ggtctgggcggcttcggtgcgctgtgtgcattgccgcaaaaatatcgtgaacccgtgctg
gtttctggcactgacggcgtaggtaccaagctgcgtctggcaatggacttaaaacgtcac
gacaccattggtattgatctggtcgccatgtgcgttaatgacctggtggtgcaaggtgca
gagccgctgtttttcctcgactattacgcaaccggaaaactggatgttgataccgcttca
gcggtgatcagcggcattgcggaaggttgtctgcaatcaggctgttcactggtgggtggc
gaaacggcagaaatgccggggatgtatcacggtgaggattacgatgtcgcgggtttctgc
gttggcgtggtagaaaaatcagaaatcatcgacggctctaaagtcagcgacggcgatgtg
ctgattgcactcggttccagcggtccacactcgaacggctattcgctggtgcgcaaaatt
cttgaagtcagcggttgtgatccgcaaaccaccgaacttgatggtaagccattagccgat
catctgctggcaccgacccgcatttacgtgaagtcagtgctggagttgattgaaaaggtc
gatgtgcatgccattgcgcacctgaccggcggcggcttctgggaaaacattccgcgcgta
ttgccagataatactcaggcagtgattgatgaatcttcctggcagtggccggaagtgttc
aactggctgcaaacggcaggtaacgttgagcaccatgaaatgtatcgcaccttcaactgc
ggcgtcgggatgattattgccctgcctgctccggaagtggacaaagccctcgccctgctc
aatgccaacggtgaaaacgcgtggaaaatcggtatcatcaaagcctctgattccgaacaa
cgcgtggttatcgaataa
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