Escherichia coli K-12 W3110: JW2636
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Entry
JW2636 CDS
T00068
Symbol
gabD
Name
(GenBank) succinate-semialdehyde dehydrogenase I, NADP-dependent
KO
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00250
Alanine, aspartate and glutamate metabolism
ecj00310
Lysine degradation
ecj00350
Tyrosine metabolism
ecj00650
Butanoate metabolism
ecj00760
Nicotinate and nicotinamide metabolism
ecj01100
Metabolic pathways
ecj01120
Microbial metabolism in diverse environments
Module
ecj_M00027
GABA (gamma-Aminobutyrate) shunt
ecj_M00956
Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
JW2636 (gabD)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
JW2636 (gabD)
00310 Lysine degradation
JW2636 (gabD)
00350 Tyrosine metabolism
JW2636 (gabD)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
JW2636 (gabD)
Enzymes [BR:
ecj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
JW2636 (gabD)
1.2.1.20 glutarate-semialdehyde dehydrogenase
JW2636 (gabD)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
JW2636 (gabD)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
BAA16524
UniProt:
P25526
Structure
PDB
PDBj
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Position
2789929..2791377
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AA seq
482 aa
AA seq
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MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDG
VYDRFAEKLQQAVSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
HERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaaacttaacgacagtaacttattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggtgaagccatcgacgtcaccaatccggcgaacggcgacaagctgggt
agcgtgccgaaaatgggcgcggatgaaacccgcgccgctatcgacgccgccaaccgcgcc
ctgcccgcctggcgcgcgctcaccgccaaagaacgcgccaccattctgcgcaactggttc
aatttgatgatggagcatcaggacgatttagcgcgcctgatgaccctcgaacagggtaaa
ccactggccgaagcgaaaggcgaaatcagctacgccgcctcctttattgagtggtttgcc
gaagaaggcaaacgcatttatggcgacaccattcctggtcatcaggccgataaacgcctg
attgttatcaagcagccgattggcgtcaccgcggctatcacgccgtggaacttcccggcg
gcgatgattacccgcaaagccggtccggcgctggcagcaggctgcaccatggtgctgaag
cccgccagtcagacgccgttctctgcgctggcgctggcggagctggcgatccgcgcgggc
gttccggctggggtatttaacgtggtcaccggttcggcgggcgcggtcggtaacgaactg
accagtaacccgctggtgcgcaaactgtcgtttaccggttcgaccgaaattggccgccag
ttaatggaacagtgcgcgaaagacatcaagaaagtgtcgctggagctgggcggtaacgcg
ccgtttatcgtctttgacgatgccgacctcgacaaagccgtggaaggcgcgctggcctcg
aaattccgcaacgccgggcaaacctgcgtctgcgccaaccgcctgtatgtgcaggacggc
gtgtatgaccgttttgccgaaaaattgcagcaggcagtgagcaaactgcacatcggcgac
gggctggataacggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggagaaaggcgcgcgcgtggtttgcggcggtaaagcg
cacgaacgcggcggcaacttcttccagccgaccattctggtggacgttccggccaacgcc
aaagtgtcgaaagaagagacgttcggccccctcgccccgctgttccgctttaaagatgaa
gctgatgtgattgcgcaagccaatgacaccgagtttggccttgccgcctatttctacgcc
cgtgatttaagccgcgtcttccgcgtgggcgaagcgctggagtacggcatcgtcggcatc
aataccggcattatttccaatgaagtggccccgttcggcggcatcaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa
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