Escherichia coli K-12 W3110: JW3745
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Entry
JW3745 CDS
T00068
Symbol
ilvA
Name
(GenBank) threonine deaminase
KO
K01754
threonine dehydratase [EC:
4.3.1.19
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00260
Glycine, serine and threonine metabolism
ecj00290
Valine, leucine and isoleucine biosynthesis
ecj01100
Metabolic pathways
ecj01110
Biosynthesis of secondary metabolites
ecj01200
Carbon metabolism
ecj01230
Biosynthesis of amino acids
Module
ecj_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
JW3745 (ilvA)
00290 Valine, leucine and isoleucine biosynthesis
JW3745 (ilvA)
Enzymes [BR:
ecj01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.19 threonine ammonia-lyase
JW3745 (ilvA)
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Motif
Pfam:
PALP
Thr_dehydrat_C
Motif
Other DBs
NCBI-ProteinID:
BAE77525
UniProt:
P04968
Structure
PDB
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Position
complement(3679806..3681350)
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AA seq
514 aa
AA seq
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MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHS
FKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDA
VRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHPMVIAGQGTLALELLQQDAHL
DRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAE
GVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYI
ALHNIRGERLAHILSGANVNFHGLRYVSERCELGEQREALLAVTIPEEKGSFLKFCQLLG
GRSVTEFNYRFADAKNACIFVGVRLSRGLEERKEILQMLNDGGYSVVDLSDDEMAKLHVR
YMVGGRPSHPLQERLYSFEFPESPGALLRFLNTLGTYWNISLFHYRSHGTDYGRVLAAFE
LGDHEPDFETRLNELGYDCHDETNNPAFRFFLAG
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atggctgactcgcaacccctgtccggtgctccggaaggtgccgaatatttaagagcagtg
ctgcgcgcgccggtttacgaggcggcgcaggttacgccgctacaaaaaatggaaaaactg
tcgtcgcgtcttgataacgtcattctggtgaagcgcgaagatcgccagccagtgcacagc
tttaagctgcgcggcgcatacgccatgatggcgggcctgacggaagaacagaaagcgcac
ggcgtgatcactgcttctgcgggtaaccacgcgcagggcgtcgcgttttcttctgcgcgg
ttaggcgtgaaggccctgatcgttatgccaaccgccaccgccgacatcaaagtcgacgcg
gtgcgcggcttcggcggcgaagtgctgctccacggcgcgaactttgatgaagcgaaagcc
aaagcgatcgaactgtcacagcagcaggggttcacctgggtgccgccgttcgaccatccg
atggtgattgccgggcaaggcacgctggcgctggaactgctccagcaggacgcccatctc
gaccgcgtatttgtgccagtcggcggcggcggtctggctgctggcgtggcggtgctgatc
aaacaactgatgccgcaaatcaaagtgatcgccgtagaagcggaagactccgcctgcctg
aaagcagcgctggatgcgggtcatccggttgatctgccgcgcgtagggctatttgctgaa
ggcgtagcggtaaaacgcatcggtgacgaaaccttccgtttatgccaggagtatctcgac
gacatcatcaccgtcgatagcgatgcgatctgtgcggcgatgaaggatttattcgaagat
gtgcgcgcggtggcggaaccctctggcgcgctggcgctggcgggaatgaaaaaatatatc
gccctgcacaacattcgcggcgaacggctggcgcatattctttccggtgccaacgtgaac
ttccacggcctgcgctacgtctcagaacgctgcgaactgggcgaacagcgtgaagcgttg
ttggcggtgaccattccggaagaaaaaggcagcttcctcaaattctgccaactgcttggc
gggcgttcggtcaccgagttcaactaccgttttgccgatgccaaaaacgcctgcatcttt
gtcggtgtgcgcctgagccgcggcctcgaagagcgcaaagaaattttgcagatgctcaac
gacggcggctacagcgtggttgatctctccgacgacgaaatggcgaagctacacgtgcgc
tatatggtcggcggacgtccatcgcatccgttgcaggaacgcctctacagcttcgaattc
ccggaatcaccgggcgcgctgctgcgcttcctcaacacgctgggtacgtactggaacatt
tctttgttccactatcgcagccatggcaccgactacgggcgcgtactggcggcgttcgaa
cttggcgaccatgaaccggatttcgaaacccggctgaatgagctgggctacgattgccac
gacgaaaccaataacccggcgttcaggttctttttggcgggttag
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