Enterobacter hormaechei subsp. hoffmannii ECNIH3: ECNIH3_03330
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Entry
ECNIH3_03330 CDS
T03350
Symbol
thrA
Name
(GenBank) aspartate kinase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ecla
Enterobacter hormaechei subsp. hoffmannii ECNIH3
Pathway
ecla00260
Glycine, serine and threonine metabolism
ecla00261
Monobactam biosynthesis
ecla00270
Cysteine and methionine metabolism
ecla00300
Lysine biosynthesis
ecla01100
Metabolic pathways
ecla01110
Biosynthesis of secondary metabolites
ecla01120
Microbial metabolism in diverse environments
ecla01230
Biosynthesis of amino acids
Module
ecla_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ecla_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ecla_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ecla00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ECNIH3_03330 (thrA)
00270 Cysteine and methionine metabolism
ECNIH3_03330 (thrA)
00300 Lysine biosynthesis
ECNIH3_03330 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ECNIH3_03330 (thrA)
Enzymes [BR:
ecla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ECNIH3_03330 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ECNIH3_03330 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AIN21368
LinkDB
All DBs
Position
690579..693041
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFAELLQGLADAQPGFPLAQLKSTVELEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHHVTVIDPVEKLLAVGHYLESAVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASAD
EDDLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQGDCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLVGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILVRETGRELELSDIVIEPVLPAEFDDSGDVSAFMA
RLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagagcgttttctgcgtgtt
gccgatatcctggaaagtaacgccaggcaggggcaggttgctaccgtgctctctgccccg
gcaaaaatcacgaaccacctggtggcgatgattgaaaaaaccatcggtggccaggatgca
cttccgaacatcagcgacgccgaacgtatcttcgctgaactgcttcaggggctggcagac
gcccagcctggcttcccgctggcgcagctgaaaagcaccgtggaactcgaatttgcccag
attaaacacgtccttcacggtatcagcctgctgggtcaatgcccggacagcatcaacgcg
gcgctgatttgccggggtgaaaaactctctatcgccatcatggcgggcgtgctggaagcg
cgcggtcaccacgtgacggtcatcgatccggttgaaaaactgctggctgtgggacactac
cttgaatccgccgtcgacattgccgagtcgacacgccgcattgcggcgagcaaaatcccg
tctgaccacatgatcctgatggcaggcttcaccgccggtaacgagaagggcgaactggtg
gtgctggggcgtaacggctctgactactccgctgccgtgctggcggcctgtttacgtgca
gactgttgtgagatctggactgacgttgatggtgtatatacctgcgacccgcgccaggtg
ccggacgccaggctgttgaagtcgatgtcgtaccaggaagcgatggagctttcctacttc
ggcgccaaagtgcttcacccacgtaccatctccccgattgcccagttccagatcccttgc
ctgattaaaaacaccggtaatccgcaggcgccgggtacgctgattggcgccagcgctgat
gaagatgacctgccggtaaaaggcatttcgaaccttaataacatggcgatgttcagcgtc
tctggcccgggtatgaaaggtatggttggcatggcggcacgcgtatttgcggccatgtcc
cgtaacgggatctccgtggtgctgatcacgcagtcttcttccgaatacagcatcagcttc
tgcgtcccgcagggcgattgcctgcgcgcccgtcgcgcgctggaagaagagttctacctg
gagctgaaagaagagctgctggagccgctctcgattcaggagcgtctggccgtgatctcc
gtggtaggcgacggcatgcgcaccctgcgcggaatctccgccaaattctttgccgccctg
gcgcgggccaatatcaatatcgtggcgattgcccagggctcatcagagcgttcaatttcc
gttgtcgtggataacgatgacgccactaccggcgtgcgcgtggtgcatcagatgctgttc
aacaccgaccaggtgattgagctgttcctggtgggcgtcggcggcgtcggcggcgcgctg
ctggagcaggtaaagcgccagcaggagtggcttaagaagaaacatatcgatttgcgcgtc
tgcggaattgcgaactcgaaagcgttgctgactaacgtccacggtctgaacctggaaaac
tggcaggcggaactggaagaggcgaaagagccgttcaacctgggtcgtctgatccgtctg
gtgaaagagtatcacctgcttaacccggtgatcgtcgactgtacctccagccaggctgtg
gccgatcagtacgcggatttcctgcgcgaaggtttccatgtggtgacgccgaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcgcgc
cgcaagtttctgtatgacaccaacgtgggcgcaggcctgccggtcatcgagaacctgcaa
aacctgctgaacgcgggcgacgaactacagcgtttctccggcatcctctccggctccctg
tcgtttatcttcggcaagctggacgaagggatgagcctttcggaagccacccgcgccgcg
cgcgagctgggctacaccgagccggatccgcgcgacgacctctccggtatggatgtggcg
cgtaagctgctgatcctggtgcgcgaaaccggccgcgagctggagctttcggatatcgtg
attgagccggtgctgccagcagaatttgatgacagcggcgacgtcagcgcttttatggcc
aggttgccgcagcttgacgacgcctttgccgcccgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaatattgaagaagacggcgtctgccgcgtgaagattgcc
gaagtggatggcaacgatccgctgtacaaggtgaaaaacggcgagaacgccctggcgttc
tacagccattattatcagccactgccgctggtacttcgcggctatggcgcagggaatgat
gtgacggcggcgggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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