Enterobacter hormaechei subsp. hoffmannii ECR091: ECR091_03575
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Entry
ECR091_03575 CDS
T03378
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
eclc
Enterobacter hormaechei subsp. hoffmannii ECR091
Pathway
eclc00290
Valine, leucine and isoleucine biosynthesis
eclc00620
Pyruvate metabolism
eclc01100
Metabolic pathways
eclc01110
Biosynthesis of secondary metabolites
eclc01210
2-Oxocarboxylic acid metabolism
eclc01230
Biosynthesis of amino acids
Module
eclc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eclc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ECR091_03575
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECR091_03575
Enzymes [BR:
eclc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ECR091_03575
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
AIN26762
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Position
complement(754437..756008)
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AA seq
523 aa
AA seq
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MSQQVVIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPIDDLARVVEAAINAGARTINIPDTVGYTMPFEF
ANIITGLYDRVPNIDKAIISVHTHDDLGLAVGNAIAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDIMDVHTRINHNEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYKDSDYNMDQLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFNVQSGSSDIATASVKLACGDEIKA
EAANGNGPVDAIYQAINRVTEYDVELVKYDLTAKGHGKDALGQVDIVVNYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcgttattttcgatactactttacgtgacggtgaacaggcattacag
gcgagcctgagtgttaaagaaaaactgcaaattgcgctggccctggaacgcatgggtgta
gacgtaatggaggtcggttttcctgtctcctcgccgggtgattttgagtcagtgcagact
atcgcccgcaccatcaaaaacagccgcgtgtgcgctctggctcgctgcgttgagaaagat
atcgatgtggccgcggaatccctgaaagttgcagaagctttccgtatccatacttttata
gccacctcccccatgcacattgcaaccaagttgcgcagcacgctggatgaagtgatcgaa
cgtgcggtgtatatggttaaacgggcgcgtaactacactgacgacgtggaattttcctgt
gaagatgcaggccgcacgccgattgacgatttggcccgtgtagtggaagccgctattaat
gccggagccagaaccatcaacatcccggataccgtcggctacaccatgccgtttgagttt
gccaacatcattactggtctgtatgaccgcgtaccaaatattgataaagccattatctct
gtacacacccacgatgacctgggtctggccgttggcaatgctatcgcggcggtgcacgcc
ggcgcgcgtcaggtagaaggcgcgatgaacggcatcggcgaacgcgcaggcaactgttcg
ctggaagaagtgatcatggcgatcaaagtgcgcaaagacatcatggacgtgcacacacgc
atcaatcacaacgaaatctggcgcaccagccagaccgtcagccagatttgcaacatgccg
atcccggccaacaaagcgattgtcggtacgggcgcgttcgctcactcttccggtatccac
caggatggggtgctgaagaaccgtgaaaactacgaaatcatgactccggaatccatcggt
ctgaaccaggttcaattgaacctgacctcacgctctggtcgcgcggcagtgaagcaccgt
atggaagagatgggctacaaggacagcgattacaacatggatcagctgtacgacgccttc
ctgaagctggcggacaagaagggccaggtgttcgattacgatctggaagcgctggcattc
atcaacaaacagcaggaagagccagagcacttccgtctggactacttcaacgtccagtcc
ggctcaagcgacatcgccaccgcctccgtgaagctggcctgcggggatgaaattaaagcg
gaagccgccaacggcaacggccctgtggatgccatttaccaggcgattaaccgcgtcact
gagtacgacgtagagctggtgaaatacgacctgacggctaaagggcacggtaaagacgcc
ctgggtcaggtggatatcgtcgtcaattataacggtcgccgcttccacggtgtgggtctg
gcgacagatatcgtcgaatcctccgcgaaagcgatggtgcatgtcctgaacaacatctgg
cgcgccgccgaagtcgaaaaagagttgcaacgcaaagctcagaataaagagaacaacaag
gaaaccgtgtga
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