Enterobacter cloacae ECNIH2: ECNIH2_04565
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Entry
ECNIH2_04565 CDS
T03471
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ecle
Enterobacter cloacae ECNIH2
Pathway
ecle00300
Lysine biosynthesis
ecle00550
Peptidoglycan biosynthesis
ecle01100
Metabolic pathways
ecle01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecle00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECNIH2_04565 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECNIH2_04565 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECNIH2_04565 (murF)
Enzymes [BR:
ecle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECNIH2_04565 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
ADH_zinc_N
Motif
Other DBs
NCBI-ProteinID:
AIE62663
UniProt:
A0A9W3Q1L7
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All DBs
Position
934540..935898
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AA seq
452 aa
AA seq
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MISITLSQAAAVLQGMLHGQDLTIEAVTTDTRKVTAGCLFVALKGERFDAHDFAQQAKDN
GAGALLVSRKLDIDLPQIVVKDTRLAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTHEHEYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPDDGIAIMNADNNDWLNWQSIIGSRKTWRFS
PNAANSDFSATNIHVTSHGTEFTLTTPTGDIEVLLPLPGRHNIANALAAAALSMAVGASH
AAIKAGLANLKAVPGRLFPIQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVMVVGD
MAELGDESEACHVQVGEAAKAAGLDRVLSAGTLSKAISDASEVGEHFADKSALIERLKAL
ITEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcattacgttaagccaggccgctgcggtattgcaggggatgctgcatggtcag
gatctaaccattgaggctgtgaccaccgacacccgtaaggtgacggcgggctgcctgttt
gtggcgctgaagggcgagcgttttgacgcccacgattttgcgcaacaggctaaagataac
ggcgcgggcgcgctgctggtcagccgtaagctcgatatcgatttgccgcagattgtggtg
aaagatacgcgcctggcgtttggcgagctggcggcatgggttcgccagcaggtgccaaca
cgcgtcgtggcgctgacgggctcgtcgggcaaaacctccgttaaagagatgacggcggcg
atccttagccagtgcggtaacacgctttatacggcgggcaaccttaataatgacatcggt
gtaccgatgacgctgctgcgcctgacccacgagcatgaatatgcggtgattgagttaggg
gctaaccatcagggcgaaatcgcctggaccgtgagcctgacgcgtccggaagcggcgctg
gtgaataacctggcggcggcacatcttgaaggttttggttcgctggccggtgtggcgaaa
gcgaaaggtgaaatttataccggcctgccggatgacggcatcgccattatgaacgccgat
aacaacgactggctgaactggcagagcatcattggttcacgcaaaacctggcgcttctca
ccgaatgcggcaaacagtgatttttcggcgaccaacattcatgtgacgtcacacggcacc
gagttcaccctcacgaccccaacgggcgacatcgaggtgctgctgcccctgcccggtcgt
cataacatcgccaatgcgcttgctgcggcagcgctctcaatggcggtaggtgcctcacac
gcggcgatcaaagcaggtctggcaaatttaaaagccgtgccggggcgtcttttcccgatc
cagctggctgaaaacaaacttctgctggatgactcctacaacgctaacgtcggctccatg
acggcggccgtgcaggtcttgtctgagatgccgggctatcgcgtgatggttgtgggcgat
atggccgagctgggtgatgaaagcgaagcctgccatgttcaggtgggtgaagcggcgaaa
gccgccgggcttgaccgcgtattgagcgcaggcacgctgagcaaggccatttccgatgcc
agtgaagttggcgaacattttgccgataaatctgcactgatcgaacgcctgaaggcattg
attacagaaaaacagattgtgactgttttagttaaaggttcacgtagtgccgccatggaa
gaggttgtgcacgcattacaggagaacgggacatgttag
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