Enterobacter cloacae GGT036: EC036_07140
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Entry
EC036_07140 CDS
T03429
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eclg
Enterobacter cloacae GGT036
Pathway
eclg00300
Lysine biosynthesis
eclg00550
Peptidoglycan biosynthesis
eclg01100
Metabolic pathways
eclg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eclg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EC036_07140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EC036_07140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EC036_07140
Enzymes [BR:
eclg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EC036_07140
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AIV28361
UniProt:
A0A0M7CJV4
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Position
780130..781488
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AA seq
452 aa
AA seq
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MISLTLGKAATLLQGTLHGQDLTIDAVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKEN
GAGALLVNRKLDIDLPQIVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHDFAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPDNGIAIMNADNNDWLNWQSIIGSRKTWRFS
PNAADSDFTATHIHVTSHGTEFTLNTPTGGIEVLLPLPGRHNIANALAAAALSMAVGATH
DAIKTGLANLKAVPGRLFPVQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVMVVGD
MAELGDESEACHIQVGEAAKAAGLDCVLSAGKLSQAISHASGVGEHFADKAALIERLKTL
IAEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatcagcttaacgctcggcaaggcggcaaccctcctgcaggggacgctgcatggtcag
gatctgaccatcgacgccgtgacgacagatacccgcaaagtgaccgccgggtgcctgttt
gtggcgctgaagggcgaacgttttgacgcccacgattttgctgaacaggcgaaagagaat
ggtgcgggtgcgctgctggtgaaccgcaaactcgatatcgatttaccgcagattgtggtg
aaggatacgcgccttgccttcggtgagctggcagcatgggttcgtcagcaggtgccagct
cgcgttgttgctctgacggggtcttcgggcaaaacgtcagtaaaagagatgacggcggcg
atcctcagtcagtgcggtaacacgctttacaccgcaggcaatctaaataatgacatcggc
gtgccgatgacattgcttcgcctcaccaaagagcatgactttgcggtgattgaattaggg
gcaaaccaccagggtgaaattgcctggacggtcagcctgacgcgtccggaggctgcgctg
gtgaacaacctggccgccgcgcatctggaaggtttcggttcacttgaaggcgtggcgaaa
gccaaaggtgagatctataccggcctgccggataacggtattgccattatgaatgccgat
aataacgactggttgaactggcagagcatcatcggttcacgtaagacgtggcgcttctcg
ccaaatgcggcagacagtgattttaccgcgacccatatccatgtgacctcgcatggtacg
gaattcacgctcaataccccaacgggaggcattgaggttctgctgccgctgccgggtcgc
cataacatcgccaatgcgcttgctgccgcggcgctgtcgatggccgtcggcgcgacacat
gacgcgatcaaaactggccttgcgaatttaaaagccgtaccgggacgtctgttcccagtc
cagcttgcagaaaacaaactgctgctggatgactcctacaacgcgaacgtcggttcgatg
acggcagccgtacaggtgttgtccgaaatgccaggctatcgcgtgatggtggttggcgat
atggccgagttgggcgatgagagcgaagcctgtcatatccaggtgggtgaagccgcgaaa
gcggccgggctggattgcgtactgagcgcaggaaaactgagccaggcgattagccatgcc
agcggtgttggcgaacattttgccgataaagccgcactgattgaacgtctgaagacgttg
attgctgaaaaacaaattgtgactgtgttagtgaaaggttcacgtagtgccgccatggaa
gaggtagtgcacgcattacaggagaacgggacatgttag
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