Escherichia coli SMS-3-5 (environmental): EcSMS35_0079
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Entry
EcSMS35_0079 CDS
T00672
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00290
Valine, leucine and isoleucine biosynthesis
ecm00620
Pyruvate metabolism
ecm01100
Metabolic pathways
ecm01110
Biosynthesis of secondary metabolites
ecm01210
2-Oxocarboxylic acid metabolism
ecm01230
Biosynthesis of amino acids
Module
ecm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EcSMS35_0079 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EcSMS35_0079 (leuA)
Enzymes [BR:
ecm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EcSMS35_0079 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
ACB19468
UniProt:
B1LG11
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All DBs
Position
complement(88592..90163)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagttattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcctgagtgcgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt
gacgtgatggaagtcggtttccccgtctcttcgccgggcgatttcgaatcggtgcagacc
atcgcccgccaggtcaaaaacagccgcgtatgtgcgttagctcgctgcgtggaaaaggat
atcgacgtggcagctgaatctctgaaagttgccgaagccttccgtatccatacctttatt
gccacttcaccaatgcacattgccaccaagctgcgtagcacgctggacgaagtaatcgaa
cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc
gaagatgccggacgcacacccattgccgatctggcgcgcgtggttgaagcggcgattaac
gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc
gccggaatcatcagcgggctgtatgaacgcgtgcctaacatcgacaaagccattatctcc
gtacatacccacgacgatttaggcctggcagttggcaactcactggcggcggtacatgcc
ggagcgcgccaggtggaaggtgcaatgaatgggatcggcgagcgagccggtaactgttcg
ctggaagaagtgatcatggcgatcaaagttcgtaaggatattctcaacgttcataccgcc
attaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatccac
caggatggtgtactgaaaaaccgtgaaaactacgaaatcatgacaccagaatctattggt
ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc
atggatgagatgggatataaagaaagtgaatataatttagacaacctgtacgacgctttc
ctgaagctggcggacaaaaaaggccaggtgtttgattacgatctggaggcgctggccttc
atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtca
ggttctaacgatattgccactgccgccgtcaaactggcctgtggcgaagaagtcaaagca
gaagccgccaacggtaacggtccggtcgatgccgtctaccaggcgataaaccgcatcact
gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg
ctgggtcaggtggatattgtcgccaactacaacggtcgccgcttccacggcgtcggcctg
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtactgaacaatatctgg
cgtgccgcagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag
gaaaccgtgtga
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