Escherichia coli SMS-3-5 (environmental): EcSMS35_1857
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Entry
EcSMS35_1857 CDS
T00672
Symbol
topA
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ecm03032
]
EcSMS35_1857 (topA)
03400 DNA repair and recombination proteins [BR:
ecm03400
]
EcSMS35_1857 (topA)
Enzymes [BR:
ecm01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
EcSMS35_1857 (topA)
DNA replication proteins [BR:
ecm03032
]
Prokaryotic type
DNA Topoisomerases
EcSMS35_1857 (topA)
DNA repair and recombination proteins [BR:
ecm03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
EcSMS35_1857 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_Ribbon_Topo
Zn_ribbon_bTOP1
Toprim
Zn_ribbon_Top1
Zn_ribbon_recom
Toprim_4
DUF1722
DUF4795
Motif
Other DBs
NCBI-ProteinID:
ACB18486
UniProt:
B1LH17
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Position
complement(1879264..1881861)
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AA seq
865 aa
AA seq
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MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPK
KDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIA
WHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVS
PLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTH
QNDKPFRPVNREQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFG
VKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKEN
SQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDF
RLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEA
SLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNY
DFTAQMENSLDQVANHEAEWKTVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCP
TCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKR
RCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHL
KMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVF
LAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYV
SSEKDGKATGWSAFYVDGKWVEGKK
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaagctcttgtcatcgttgagtccccggcaaaagccaaaacgatcaacaagtat
ctgggtagtgactacgtggtgaaatccagcgtcggtcacatccgcgatttgccgaccagt
ggctcagctgccaaaaagagtgccgactctacctccaccaagacggctaaaaagcctaaa
aaggatgaacgtggcgctctcgtcaaccgtatgggggttgacccgtggcacaattgggag
gcgcactatgaagtgttgcctggtaaagagaaggtcgtctctgaactgaaacaactggct
gaaaaagccgaccacatctatctcgcaaccgaccttgaccgcgaaggggaagccattgca
tggcacctgcgggaagtgattggtggtgatgatgcgcgctatagccgagtggtgtttaac
gaaattactaaaaacgcgatccgccaggcatttaacaaaccaggtgagctgaatattgat
cgtgttaatgcccagcaggcgcgtcgctttatggaccgcgtggtggggtatatggtttcg
ccgctgctgtggaaaaagatcgctcgtggtctgtctgccggtcgtgtgcagtcggtggcg
gttcgcctggtggtcgagcgtgagcgtgaaattaaagcgttcgtgccggaagagttctgg
gaagtcgatgccagcacgaccacgccatctggtgaagcgttggcgttacaggtcactcat
cagaacgacaaaccgttccgcccggtcaacagagaacaaactcaggctgcggtaagtctg
ctggaaaaagcgcgctacagcgtgctggaacgtgaagacaaaccgacaaccagtaaacct
ggcgctccttttattacctctacgctgcaacaagctgccagcacccgtcttggatttggc
gtgaaaaaaaccatgatgatggcgcagcgtttgtatgaagcaggctatatcacttacatg
cgtaccgactccactaacctgagtcaggacgcggtaaatatggttcgcggttatatcagc
gataattttggtaagaaatatctgccggaaagtccgaatcagtacgccagcaaagaaaac
tcacaggaagcgcacgaagcgattcgtccttctgacgtcaatgtgatggcggaatcgctg
aaggatatggaagcagatgcgcagaaactgtaccagttaatctggcgtcagttcgttgcc
tgccagatgaccccagcgaaatatgactccacgacgctgaccgttggtgcgggcgatttc
cgcctgaaagcacgcggtcgtattttgcgctttgatggctggacaaaagtgatgcctgca
ctgcgtaaaggcgatgaagatcgtatcttaccggcagtcgataaaggcgatgctctgacg
ctcgttgaactgacaccagcccagcactttaccaagccgccagcccgttttagtgaagca
tcgctggttaaagagctggaaaaacgcggtatcggtcgtccgtctacctatgcatcgatc
atttcgaccattcaggatcgtggctatgtgcgagtagaaaatcgtcgtttctatgcggaa
aaaatgggcgaaatcgtcaccgatcgccttgaagaaaatttccgtgagttaatgaactac
gacttcaccgcgcagatggaaaacagcctcgaccaggtggcaaatcacgaagcagagtgg
aaaactgtactggatcacttcttctcggatttcactcagcagttagataaagctgaaaaa
gatccggaagagggtggtatgcgcccgaaccagatggttctgaccagcattgactgcccg
acttgtggtcgcaaaatggggattcgcacagcgagcaccggggtattccttggctgttct
ggttatgcgctgccgccgaaagagcgttgcaaaaccaccattaacctggtgccggaaaac
gaagtgctgaacgtgctggaaggcgaagacgctgaaaccaacgcgctgcgcgcaaaacgt
cgttgcccgaaatgcggcacggcgatggacagctatctcatcgatccgaaacgtaagttg
catgtctgtggtaataacccaacctgcgacggttacgagatcgaagagggcgaattccgc
attaaaggttatgacggcccgatcgttgagtgtgaaaaatgtggctctgaaatgcacctg
aaaatggggcgtttcggtaaatacatggcctgcaccaacgaagagtgtaaaaacacacgt
aagattttacgtaacggcgaagtggcaccaccgaaagaagatccggtgccattacctgag
ttgccgtgcgaaaaatcagatgcttatttcgtgctgcgtgacggtgctgccggtgtgttc
ctggctgccaacactttcccgaaatcgcgtgaaacacgtgcgccactggtggaagagctt
tatcgcttccgcgaccgtctgccggaaaaactgcgttatctggccgatgcgccacagcag
gatccggaaggtaataagaccatggttcgctttagccgtaaaaccaaacagcaatatgtc
tcttcggaaaaagacggaaaggcgactggctggtcagcattttatgttgatggcaaatgg
gttgaaggaaaaaaataa
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