Escherichia coli SMS-3-5 (environmental): EcSMS35_2710
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Entry
EcSMS35_2710 CDS
T00672
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00230
Purine metabolism
ecm01100
Metabolic pathways
ecm01110
Biosynthesis of secondary metabolites
Module
ecm_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EcSMS35_2710 (purL)
Enzymes [BR:
ecm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
EcSMS35_2710 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
ACB18130
UniProt:
B1LP70
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Position
complement(2786875..2790762)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSIDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTREVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTSASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQEMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatatcgcccataattgcggtcta
caacaggtaaaccgccttgagcgcggcgtggcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggtgaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagttgtttgctcatcatcagccaaccccggtcaccagc
attgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggtctg
gcgctggcggaagatgagattgactatctgcaggatgcgttcacaaagcttggtcgtaac
ccgaacgacatcgagctgtatatgttcgcgcaggcgaactccgagcactgccgtcacaaa
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaacaccttcgaaaccacgccagaccacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggtcgctactttgccgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagttgaaacccacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccggccgcggcgcgaagccgaaagctggcctggtcggtttctccgtatccaacctg
cgtattcctggctttgaacaaccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgacagaaggtccgctgggcggcgcggcatttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacctatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttctatggcatctggtcag
tctgatgcggacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgagccaggcatgagcccgctg
gagatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgaacgagcaccctacgcggtgattggcgaggcc
accgaagaattacatctttctctgcacgatcgtcattttgataatcaacccatcgatctg
ccgctggacgtactgcttggtaaaacgccgaagatgacccgcgaagtacaaacgctgaaa
gcgaagggtgatgcgctggttcgtgaagggattaccattgctgacgcggtgaaacgcgtg
ctgcacctgccgaccgtggcggagaaaactttcctggtgaccattggtgaccgcagcgta
accggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgc
gcggtcacttccgccagcctcgatagctactacggcgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgtgtggaagatgtgcgtcacaccatcacgccgcagctttct
accgaagataacgcattactgctgattgatctgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtt
gcccaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctc
gcgtaccacgaccgctcggatggcggcctgctggtaacgctggcggaaatggcgtttgct
ggtcattgtggcattgacgcagatatcgcctctctgggtgacgatcgcctggctgcgttg
tttaacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcggtcgag
tccgtactggcacagcatggacttgcggattgcgtccattatgtagggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcactacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggaacatcaggcgaaatctaacgacgccgatccgggcctgaatgtgaaa
ctgtcgtttgatatcaacgaagatgtggcagcaccgtatattgccaccggtgcgcgtccg
aaagttgccgtgctgcgtgagcagggtgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgcaatcgatgtgcatatgagcgacctgctggctggacgcacg
ggactggaggatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtactg
ggtgccggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgcgaactgatcccaggcagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcctggttgaagtaacccaaagcccgtctctg
ctgttgcaggagatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcgctggaaagtaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcggtcacgactgaaagtggtcgagtcactattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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