Escherichia coli SMS-3-5 (environmental): EcSMS35_4137
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Entry
EcSMS35_4137 CDS
T00672
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00290
Valine, leucine and isoleucine biosynthesis
ecm00770
Pantothenate and CoA biosynthesis
ecm01100
Metabolic pathways
ecm01110
Biosynthesis of secondary metabolites
ecm01210
2-Oxocarboxylic acid metabolism
ecm01230
Biosynthesis of amino acids
Module
ecm_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
ecm_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EcSMS35_4137 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
EcSMS35_4137 (ilvD)
Enzymes [BR:
ecm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
EcSMS35_4137 (ilvD)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ACB18610
UniProt:
B1LLU6
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Position
4233268..4235118
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDVMLTQDDSVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKEG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctgcgcgatctcggtaaactggtc
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggattgccatgggccacggggggatgctttattcgctgccatctcgcgaactgatc
gctgattccgttgagtatatggtcaatgctcactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatc
aagctcgatctggttgatgcgatgatccagggggcagacccgaaagtttctgactcccaa
agcgatcaggttgaacgttccgcatgcccaacctgcggttcctgctccgggatgtttacc
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaactcacgccgaccgtaagcagctgttcctcaatgccggtaaacgcattgtt
gaattgaccaaacgttactacgagcaaaatgacgaaagtgcactgccgcgtaatatcgcc
agtaaggcggcgtttgaaaacgccatgacgctggatatcgcgatgggtggatcgactaac
actgtacttcacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgacaaactttcgcgtaaagtcccgcagttatgcaaagttgcgccgagcacccagaaa
taccatatggaagatgttcatcgtgctggtggtgttatcggtattctcggcgaactggat
cgcgcggggttactgaaccgtgatgtgaaaaacgtgcttggcctgacgttgccacaaacg
ctggaacaatacgacgttatgctgacccaggatgactcggtaaaaaatatgttccgcgct
ggccctgcgggcattcgtactacacaggcattctcgcaggattgccgttgggattctctc
gatgacgatcgcgccaatggctgtatccgctcgctggaacacgcctacagcaaagaaggt
ggtctggcggtgctgtacggtaatttcgcagaaaacggctgcatcgttaaaaccgcgggc
gtcgatgacagcatcctcaaattcaccggcccggcgaaagtgtacgaaagccaggatgac
gcggtagaagcgattctcggcggcaaagttgtcgctggcgatgtagtggtgatccgctat
gaaggcccgaaaggcggtccggggatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatgggtctcggtaaagcctgcgcgctgatcaccgacggacgcttctccggcggcacc
tctggcctttctatcggccacgtctcaccggaagcggcaagcggcggcagcattggcctg
attgaagacggcgacctgatcgccatcgacattccgaaccgtggtattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcgtggcgacaaagcctgg
acgccgaaaaaccgtgaacgccaggtttcctttgcgctgcgtgcctacgccagcctggca
accagcgccgacaaaggtgcggtgcgcgataaatcgaaactggggggttaa
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