KEGG   Escherichia coli K-12 MG1655: b0032
Entry
b0032             CDS       T00007                                 
Symbol
carA
Name
(RefSeq) carbamoyl-phosphate synthetase small subunit
  KO
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00220  Arginine biosynthesis
eco00240  Pyrimidine metabolism
eco00250  Alanine, aspartate and glutamate metabolism
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01240  Biosynthesis of cofactors
Module
eco_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    b0032 (carA)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    b0032 (carA)
   00220 Arginine biosynthesis
    b0032 (carA)
Enzymes [BR:eco01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     b0032 (carA)
SSDB
Motif
Pfam: GATase CPSase_sm_chain Peptidase_C26 DJ-1_PfpI
Other DBs
NCBI-GeneID: 949025
NCBI-ProteinID: NP_414573
Pasteur: carA
RegulonDB: RDBECOLIGNC00130
ECOCYC: EG10134
ASAP: ABE-0000118
UniProt: P0A6F1
Structure
LinkDB
Position
29651..30799
AA seq 382 aa
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHI
GNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTR
LLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGG
LPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSN
GPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDV
EKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGP
HDAAPLFDHFIELIEQYRKTAK
NT seq 1149 nt   +upstreamnt  +downstreamnt
ttgattaagtcagcgctattggttctggaagacggaacccagtttcacggtcgggccata
ggggcaacaggttcggcggttggggaagtcgttttcaatacttcaatgaccggttatcaa
gaaatcctcactgatccttcctattctcgtcaaatcgttactcttacttatccccatatt
ggcaatgtcggcaccaatgacgccgatgaagaatcttctcaggtacatgcacaaggtctg
gtgattcgcgacctgccgctgattgccagcaacttccgtaataccgaagacctctcttct
tacctgaaacgccataacatcgtggcgattgccgatatcgatacccgtaagctgacgcgt
ttactgcgcgagaaaggcgcacagaatggctgcattatcgcgggcgataacccggatgcg
gcgctggcgttagaaaaagcccgcgcgttcccaggtctgaatggcatggatctggcaaaa
gaagtgaccaccgcagaagcctatagctggacacaagggagctggacgttgaccggtggc
ctgccagaagcgaaaaaagaagacgagctgccgttccacgtcgtggcttatgattttggt
gccaagcgcaacatcctgcggatgctggtggatagaggctgtcgcctgaccatcgttccg
gcgcaaacttctgcggaagatgtgctgaaaatgaatccagacggcatcttcctctccaac
ggtcctggcgacccggccccgtgcgattacgccattaccgccatccagaaattcctcgaa
accgatattccggtattcggcatctgtctcggtcatcagctgctggcgctggcgagcggt
gcgaagactgtcaaaatgaaatttggtcaccacggcggcaaccatccggttaaagatgtg
gagaaaaacgtggtaatgatcaccgcccagaaccacggttttgcggtggacgaagcaaca
ttacctgcaaacctgcgtgtcacgcataaatccctgttcgacggtacgttacagggcatt
catcgcaccgataaaccggcattcagcttccaggggcaccctgaagccagccctggtcca
cacgacgccgcgccgttgttcgaccactttatcgagttaattgagcagtaccgtaaaacc
gctaagtaa

KEGG   Escherichia coli K-12 MG1655: b0033
Entry
b0033             CDS       T00007                                 
Symbol
carB
Name
(RefSeq) carbamoyl-phosphate synthetase large subunit
  KO
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00220  Arginine biosynthesis
eco00240  Pyrimidine metabolism
eco00250  Alanine, aspartate and glutamate metabolism
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01240  Biosynthesis of cofactors
Module
eco_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    b0033 (carB)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    b0033 (carB)
   00220 Arginine biosynthesis
    b0033 (carB)
Enzymes [BR:eco01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     b0033 (carB)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D3 MGS ATP-grasp Dala_Dala_lig_C ATP-grasp_3 ATP-grasp_4 ATPgrasp_Ter CoA_binding_2 BamE
Other DBs
NCBI-GeneID: 944775
NCBI-ProteinID: NP_414574
Pasteur: carB
RegulonDB: RDBECOLIGNC00131
ECOCYC: EG10135
ASAP: ABE-0000121
UniProt: P00968
Structure
LinkDB
Position
30817..34038
AA seq 1073 aa
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEM
ADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATA
DAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGG
IAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIP
RFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEA
LTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
ITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDT
AYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVN
CNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVP
VIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVL
GGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIME
HIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLI
EVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKF
PGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDL
AAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGR
RAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
NT seq 3222 nt   +upstreamnt  +downstreamnt
atgccaaaacgtacagatataaaaagtatcctgattctgggtgcgggcccgattgttatc
ggtcaggcgtgtgagtttgactactctggcgcgcaagcgtgtaaagccctgcgtgaagag
ggttaccgcgtcattctggtgaactccaacccggcgaccatcatgaccgacccggaaatg
gctgatgcaacctacatcgagccgattcactgggaagttgtacgcaagattattgaaaaa
gagcgcccggacgcggtgctgccaacgatgggcggtcagacggcgctgaactgcgcgctg
gagctggaacgtcagggcgtgttggaagagttcggtgtcaccatgattggtgccactgcc
gatgcgattgataaagcagaagaccgccgtcgtttcgacgtagcgatgaagaaaattggt
ctggaaaccgcgcgttccggtatcgcacacacgatggaagaagcgctggcggttgccgct
gacgtgggcttcccgtgcattattcgcccatcctttaccatgggcggtagcggcggcggt
atcgcttataaccgtgaagagtttgaagaaatttgcgcccgcggtctggatctctctccg
accaaagagttgctgattgatgagtcgctgatcggctggaaagagtacgagatggaagtg
gtgcgtgataaaaacgacaactgcatcatcgtctgctctatcgaaaacttcgatgcgatg
ggcatccacaccggtgactccatcactgtcgcgccagcccaaacgctgaccgacaaagaa
tatcaaatcatgcgtaacgcctcgatggcggtgctgcgtgaaatcggcgttgaaaccggt
ggttccaacgttcagtttgcggtgaacccgaaaaacggtcgtctgattgttatcgaaatg
aacccacgcgtgtcccgttcttcggcgctggcgtcgaaagcgaccggtttcccgattgct
aaagtggcggcgaaactggcggtgggttacaccctcgacgaactgatgaacgacatcact
ggcggacgtactccggcctccttcgagccgtccatcgactatgtggttactaaaattcct
cgcttcaacttcgaaaaattcgccggtgctaacgaccgtctgaccactcagatgaaatcg
gttggcgaagtgatggcgattggtcgcacgcagcaggaatccctgcaaaaagcgctgcgc
ggcctggaagtcggtgcgactggattcgacccgaaagtgagcctggatgacccggaagcg
ttaaccaaaatccgtcgcgaactgaaagacgcaggcgcagatcgtatctggtacatcgcc
gatgcgttccgtgcgggcctgtctgtggacggcgtcttcaacctgaccaacattgaccgc
tggttcctggtacagattgaagagctggtgcgtctggaagagaaagtggcggaagtgggc
atcactggcctgaacgctgacttcctgcgccagctgaaacgcaaaggctttgccgatgcg
cgcttggcaaaactggcgggcgtacgcgaagcggaaatccgtaagctgcgtgaccagtat
gacctgcacccggtttataagcgcgtggatacctgtgcggcagagttcgccaccgacacc
gcttacatgtactccacttatgaagaagagtgcgaagcgaatccgtctaccgaccgtgaa
aaaatcatggtgcttggcggcggcccgaaccgtatcggtcagggtatcgaattcgactac
tgttgcgtacacgcctcgctggcgctgcgcgaagacggttacgaaaccattatggttaac
tgtaacccggaaaccgtctccaccgactacgacacttccgaccgcctctacttcgagccg
gtaactctggaagatgtgctggaaatcgtgcgtatcgagaagccgaaaggcgttatcgtc
cagtacggcggtcagaccccgctgaaactggcgcgcgcgctggaagctgctggcgtaccg
gttatcggcaccagcccggatgctatcgaccgtgcagaagaccgtgaacgcttccagcat
gcggttgagcgtctgaaactgaaacaaccggcgaacgccaccgttaccgctattgaaatg
gcggtagagaaggcgaaagagattggctacccgctggtggtacgtccgtcttacgttctc
ggcggtcgggcgatggaaatcgtctatgacgaagctgacctgcgtcgctacttccagacg
gcggtcagcgtgtctaacgatgcgccagtgttgctggaccacttcctcgatgacgcggta
gaagttgacgtggatgccatctgcgacggcgaaatggtgctgattggcggcatcatggag
catattgagcaggcgggcgtgcactccggtgactccgcatgttctctgccagcctacacc
ttaagtcaggaaattcaggatgtgatgcgccagcaggtgcagaaactggccttcgaattg
caggtgcgcggcctgatgaacgtgcagtttgcggtgaaaaacaacgaagtctacctgatt
gaagttaacccgcgtgcggcgcgtaccgttccgttcgtctccaaagccaccggcgtaccg
ctggcaaaagtggcggcgcgcgtgatggctggcaaatcgctggctgagcagggcgtaacc
aaagaagttatcccgccgtactactcggtgaaagaagtggtgctgccgttcaataaattc
ccgggcgttgacccgctgttagggccagaaatgcgctctaccggggaagtcatgggcgtg
ggccgcaccttcgctgaagcgtttgccaaagcgcagctgggcagcaactccaccatgaag
aaacacggtcgtgcgctgctttccgtgcgcgaaggcgataaagaacgcgtggtggacctg
gcggcaaaactgctgaaacagggcttcgagctggatgcgacccacggcacggcgattgtg
ctgggcgaagcaggtatcaacccgcgtctggtaaacaaggtgcatgaaggccgtccgcac
attcaggaccgtatcaagaatggcgaatatacctacatcatcaacaccacctcaggccgt
cgtgcgattgaagactcccgcgtgattcgtcgcagtgcgctgcaatataaagtgcattac
gacaccaccctgaacggcggctttgccaccgcgatggcgctgaatgccgatgcgactgaa
aaagtaatttcggtgcaggaaatgcacgcacagatcaaataa

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