Escherichia coli K-12 MG1655: b0074 Help Entry b0074             CDS       T00007                                  Symbol leuA Name (RefSeq) 2-isopropylmalate synthase   KO K01649   2-isopropylmalate synthase [EC:2.3.3.13] Organism eco  Escherichia coli K-12 MG1655 Pathway eco00290   Valine, leucine and isoleucine biosynthesis eco00620   Pyruvate metabolism eco01100   Metabolic pathways eco01110   Biosynthesis of secondary metabolites eco01210   2-Oxocarboxylic acid metabolism eco01230   Biosynthesis of amino acids Module eco_M00432   Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate Brite KEGG Orthology (KO) [BR:eco00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     b0074 (leuA)   09105 Amino acid metabolism    00290 Valine, leucine and isoleucine biosynthesis     b0074 (leuA) Enzymes [BR:eco01000]  2. Transferases   2.3  Acyltransferases    2.3.3  Acyl groups converted into alkyl groups on transfer     2.3.3.13  2-isopropylmalate synthase      b0074 (leuA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HMGL-like LeuA_dimer HCS_D2 IPMS_D2 Motif Other DBs NCBI-GeneID:  947465 NCBI-ProteinID:  NP_414616 Pasteur:  leuA RegulonDB:  RDBECOLIGNC01203 ECOCYC:  EG11226 ASAP:  ABE-0000267 UniProt:  P09151 LinkDB All DBs Position complement(81958..83529) Genome browser AA seq 523 aa AA seqDB search MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA EAANGNGPVDAVYQAINRITEYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV NT seq 1572 nt NT seq  +upstreamnt  +downstreamnt atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt gacgtgatggaagtcggtttccccgtctcttcgccgggcgattttgaatcggtgcaaacc atcgcccgccaggttaaaaacagccgcgtatgtgcgttagctcgctgcgtggaaaaagat atcgacgtggcggccgaatccctgaaagtcgccgaagccttccgtattcatacctttatt gccacttcgccaatgcacatcgccaccaagctgcgcagcacgctggacgaggtgatcgaa cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc gaagatgccgggcgtacacccattgccgatctggcgcgagtggtcgaagcggcgattaat gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc gccggaatcatcagcggcctgtatgaacgcgtgcctaacatcgacaaagccattatctcc gtacatacccacgacgatttgggcctggcggtcggaaactcactggcggcggtacatgcc ggtgcacgccaggtggaaggcgcaatgaacgggatcggcgagcgtgccggaaactgttcc ctggaagaagtcatcatggcgatcaaagttcgtaaggatattctcaacgtccacaccgcc attaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatacac caggatggcgtgctgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc atggatgagatggggtataaagaaagtgaatataatttagacaatttgtacgatgctttc ctgaagctggcggacaaaaaaggtcaggtgtttgattacgatctggaggcgctggccttc atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtct ggctctaacgatatcgccaccgccgccgtcaaactggcctgtggcgaagaagtcaaagca gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcaattaaccgcatcact gaatataacgtcgaactggtgaaatacagcctgaccgccaaaggccacggtaaagatgcg ctgggtcaggtggatatcgtcgctaactacaacggtcgccgcttccacggcgtcggcctg gctaccgatattgtcgagtcatctgccaaagccatggtgcacgttctgaacaatatctgg cgtgccgcagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag gaaaccgtgtga

DBGET integrated database retrieval system