KEGG   Escherichia coli K-12 MG1655: b1288
Entry
b1288             CDS       T00007                                 
Symbol
fabI
Name
(RefSeq) enoyl-[acyl-carrier-protein] reductase
  KO
K00208  enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00061  Fatty acid biosynthesis
eco00780  Biotin metabolism
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01212  Fatty acid metabolism
eco01240  Biosynthesis of cofactors
Module
eco_M00083  Fatty acid biosynthesis, elongation
eco_M00572  Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    b1288 (fabI)
  09108 Metabolism of cofactors and vitamins
   00780 Biotin metabolism
    b1288 (fabI)
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    b1288 (fabI)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:eco01004]
    b1288 (fabI)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.9  enoyl-[acyl-carrier-protein] reductase (NADH)
     b1288 (fabI)
    1.3.1.10  enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
     b1288 (fabI)
Lipid biosynthesis proteins [BR:eco01004]
 Fatty acid synthase
  Component type
   b1288 (fabI)
SSDB
Motif
Pfam: adh_short_C2 adh_short SDR KR
Other DBs
NCBI-GeneID: 945870
NCBI-ProteinID: NP_415804
Pasteur: fabI
RegulonDB: RDBECOLIGNC01481
ECOCYC: EG11528
ASAP: ABE-0004327
UniProt: P0AEK4
Structure
LinkDB
Position
complement(1350251..1351039)
AA seq 262 aa
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV
LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS
SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE
GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI
SGEVVHVDGGFSIAAMNELELK
NT seq 789 nt   +upstreamnt  +downstreamnt
atgggttttctttccggtaagcgcattctggtaaccggtgttgccagcaaactatccatc
gcctacggtatcgctcaggcgatgcaccgcgaaggagctgaactggcattcacctaccag
aacgacaaactgaaaggccgcgtagaagaatttgccgctcaattgggttctgacatcgtt
ctgcagtgcgatgttgcagaagatgccagcatcgacaccatgttcgctgaactggggaaa
gtttggccgaaatttgacggtttcgtacactctattggttttgcacctggcgatcagctg
gatggtgactatgttaacgccgttacccgtgaaggcttcaaaattgcccacgacatcagc
tcctacagcttcgttgcaatggcaaaagcttgccgctccatgctgaatccgggttctgcc
ctgctgaccctttcctaccttggcgctgagcgcgctatcccgaactacaacgttatgggt
ctggcaaaagcgtctctggaagcgaacgtgcgctatatggcgaacgcgatgggtccggaa
ggtgtgcgtgttaacgccatctctgctggtccgatccgtactctggcggcctccggtatc
aaagacttccgcaaaatgctggctcattgcgaagccgttaccccgattcgccgtaccgtt
actattgaagatgtgggtaactctgcggcattcctgtgctccgatctctctgccggtatc
tccggtgaagtggtccacgttgacggcggtttcagcattgctgcaatgaacgaactcgaa
ctgaaataa

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